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Search Results for " Prostate "

386

阻害剤

天然化合物

100

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T80552	Prostate Specific Antigen Substrate
	Prostate Specific Antigen Substrate is a fluorescent substrate specific to prostate specific antigen (PSA) and facilitates the detection of PSA enzymatic activity [1].
T23189	prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]		Others
	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.		Others
T22263	Bavdegalutamide	ARV-110	Androgen Receptor
	Bavdegalutamide (ARV-110) is a PROTAC degrader of androgen receptor (AR). Bavdegalutamide can be used in studies about prostate cancer. Bavdegalutamide shows oral activity and selectivity and facilitates the ubiquitinati...		Androgen Receptor
T0380	Bicalutamide	ICI-176334	Androgen Receptor , Autophagy
	Bicalutamide (ICI-176334), a synthetic, nonsteroidal antiandrogen, competitively binds to cytosolic androgen receptors in target tissues, thereby inhibiting the receptor binding of androgens.		Androgen Receptor , Autophagy
T7690	2-hydroxy Flutamide		Androgen Receptor
	2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer		Androgen Receptor
T8858	DTHIB		HSP
	DTHIB robustly inhibits the HSF1 cancer gene signature and prostate cancer cell proliferation.		HSP
T60051	VPC-18005		Others
	VPC-18005 is a luciferase inhibitor. VPC-18005 inhibits ERG-induced transcription and interacts directly with the ERG-ETS domain thereby disrupting the ERG binding to DNA.		Others
T3160	HUHS015		Others
	HUHS015 is a potent PCA-1/ALKBH3 inhibitor.		Others
T9721	ML339		CXCR
	ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.		CXCR
T8217	Enzalutamide carboxylic acid		Androgen Receptor , Drug Metabolite
	Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .		Androgen Receptor , Drug Metabolite
T21740	RD162		Androgen Receptor
	RD162 is a non-steroidal antiandrogen (NSAA) specifically binding to the androgen receptor (AR).		Androgen Receptor
T25492	Hepln-13	Hepln 13,Hepln13	c-Met/HGFR
	Hepln-13 is a hepsin inhibitor that acts by hindering prostate cancer bone metastasis.		c-Met/HGFR
T39695	ARD-2128		Androgen Receptor , PROTACs
	ARD-2128 is a highly potent, orally bioavailable PROTAC (proteolysis-targeting chimera) degrader of the androgen receptor (AR), effectively diminishing AR protein levels, suppressing AR-regulated gene expression in tumor...		Androgen Receptor , PROTACs
T12928	SK33		Androgen Receptor
	SK33 is a potent and tissue selective anti-androgen agent. SK33 reduces androgen receptor (AR) transcriptional activity.		Androgen Receptor
T9266	Fatostatin		Lipid , Fatty Acid Synthase
	Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.		Lipid , Fatty Acid Synthase
T13273	UT-34		Androgen Receptor
	UT-34 is a selective and orally active antagonist of second-generation pan-androgen receptor (AR) and degrader(IC50s of 211.7 nM, 262.4 nM and 215.7 nM for wild-type, F876L and W741L AR, respectively), and has anti-prost...		Androgen Receptor
T6889	MI-136		Apoptosis , Epigenetic Reader Domain , Androgen Receptor
	MI-136 inhibits expression of androgen receptor (AR) target genes that DHT induced.		Apoptosis , Epigenetic Reader Domain , Androgen Receptor
T6002	Enzalutamide	MDV3100	Androgen Receptor , Autophagy
	Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist (IC50=36 nM in LNCaP). Enzalutamide activates autophagy, has antitumor activity, and is commonly used in the treatment of desmoplasia-resistant prostate canc...		Androgen Receptor , Autophagy
T6400	AZD3514		Androgen Receptor
	AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.		Androgen Receptor
T1855	ZCL278	ZCL 278	CDK , Ras
	ZCL278 is a selective Cdc42 GTPase inhibitor.		CDK , Ras
T38684	AKR1C3-IN-4	AKR1C3-IN-4	NADPH
	AKR1C3-IN-4 is a potent and selective inhibitor of aldo-keto reductase 1C3 (AKR1C3) with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research.		NADPH
T2014	CCG-1423	CCG1423	LRRK2 , Rho , Ras
	CCG-1423, a selective RhoA pathway inhibitor, suppresses SRF-mediated transcription.		LRRK2 , Rho , Ras
T0272	Nilutamide	RU23908	Androgen Receptor
	Nilutamide (RU23908), an antineoplastic hormonal agent, is mainly used in the treatment of prostate Y. Nilutamide is a pure, nonsteroidal anti-androgen with affinity for androgen receptors, but not for estrogen, progesto...		Androgen Receptor
T6308	Stattic	STAT3 Inhibitor V	Apoptosis , STAT
	Stattic (STAT3 Inhibitor V) is a STAT3 inhibitor (IC50=5.1 μM) that selectively inhibits STAT3 activation, dimerization, and nuclear translocation. Stattic has antitumor activity and induces apoptosis.		Apoptosis , STAT
T9246	JNJ-63576253		Androgen Receptor
	JNJ-63576253 is a Clinical Stage Androgen Receptor Antagonist for F877L Mutant and Wild-Type Castration-Resistant Prostate Cancer (mCRPC).		Androgen Receptor
T28410	PHPS1	PHPS-1,PHPS 1	Phosphatase
	PHPS1 is an inhibitor of Shp2. PHPS1 efficiently inhibits activation of Erk1/2 by the leukemia-associated Shp2 mutant, Shp2-E76K, and blocks the anchorage-independent growth of a variety of human tumor cell lines.		Phosphatase
T10717	Inobrodib	CBP-IN-1	Epigenetic Reader Domain
	Inobrodib (CBP-IN-1) is a potent inhibitor of p300/CBP bromodomain.		Epigenetic Reader Domain
T6916	OICR-9429	OICR 9429	Histone Methyltransferase , JAK
	OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro.		Histone Methyltransferase , JAK
T16522	Phenoxodiol	Dehydroequol,Idronoxil,Haginin E	Apoptosis , IAP , Caspase , Topoisomerase , p53
	Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apop...		Apoptosis , IAP , Caspase , Topoisomerase , p53
T36841	IPI-9119		Fatty Acid Synthase
	IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).		Fatty Acid Synthase
T1267	Abacavir	Epzicom,Ziagen,Abacavir sulfate	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir (Ziagen) is a nucleoside reverse transcriptase inhibitor analog of guanosine. This agent decreases HIV viral loads, retards or prevents the damage to the immune system, and reduces the risk of developing AIDS.		Apoptosis , HIV Protease , Reverse Transcriptase
T2108	Andarine	S-4,GTx-007	Androgen Receptor
	Andarine (GTx-007) (S-4) is an active partial agonist and an investigational selective androgen receptor modulator (SARM).		Androgen Receptor
T27730	KGP94	KGP-94,KGP 94	Cysteine Protease
	KGP94 is an inhibitor of cysteine protease Cathepsin L(CTSL).		Cysteine Protease
T7188	Piclidenoson	CF-101,IB-MECA	Apoptosis , Adenosine Receptor
	Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.		Apoptosis , Adenosine Receptor
T1448	Dasatinib	BMS-354825	Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
	Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive. Dasatinib has antitumor activity and is used in the treatment of leukemia and ly...		Apoptosis , Bcr-Abl , Src , c-Kit , Autophagy
T0696	Naftopidil	KT-611,BM-15275	Adrenergic Receptor
	Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker.		Adrenergic Receptor
T6367	Abacavir sulfate	Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen	Apoptosis , HIV Protease , Reverse Transcriptase
	Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity		Apoptosis , HIV Protease , Reverse Transcriptase
T9179	CLP-3094	2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE	Androgen Receptor
	CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) is a potent androgen receptor BF3 (binding function 3) inhibitor. BF3-IN-1 inhibits AR transcriptional activity with IC50 of 4 μM. CLP-3094 is a selective and potent GP...		Androgen Receptor
T3630	Relugolix	RVT-601,TAK-385	GNRH Receptor
	Relugolix (RVT-601) is an orally available, non-peptide gonadotropin-releasing hormone (GnRH or luteinizing hormone-releasing hormone (LHRH)) antagonist, with potential antineoplastic activity. Relugolix competitively bi...		GNRH Receptor
T8933	JNJ-63576253 free base	TRC253,JNJ-63576253	Androgen Receptor
	JNJ-63576253 free base (TRC253) is a potent and orally active full antagonist of androgen receptor (AR), with IC50s of 37 and 54 nM for F877L mutant AR and wild-type AR in LNCaP cells. JNJ-63576253 can be used for the re...		Androgen Receptor
T20681	Estramustine	NSC-89201,NSC 89201,LEO 275,LEO275,NSC89201,LEO-275	Microtubule Associated
	Estramustine (LEO-275) is a nitrogen mustard linked to estradiol, usually as phosphate. Estramustine has been used to treat prostatic neoplasms; also has radiation protective properties. Estramustine is selectively taken...		Microtubule Associated
T1167	Cyproterone acetate	Androcur,Cyproterone 17-O-acetate	Androgen Receptor
	Cyproterone acetate (Cyproterone 17-O-acetate) binds the androgen receptor (AR), thereby preventing androgen-induced receptor activation in target tissues and inhibiting the growth of testosterone-sensitive tumor cells. ...		Androgen Receptor
T9245	TRPM4-IN-1	CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.		TRP/TRPV Channel
T1448L	Dasatinib monohydrate	BMS-354825 Monohydrate	Apoptosis , Bcr-Abl , Src , c-Kit , Ephrin Receptor , Autophagy
	Dasatinib monohydrate (BMS-354825 Monohydrate) is an orally bioavailable synthetic small molecule-inhibitor of SRC-family protein-tyrosine kinases. Dasatinib monohydrate binds to and inhibits the growth-promoting activit...
T2275	YK-4-279		Apoptosis , DNA/RNA Synthesis
	YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.		Apoptosis , DNA/RNA Synthesis
T6832	Fatostatin hydrobromide	Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin	NPC1L1 , Fatty Acid Synthase
	Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.		NPC1L1 , Fatty Acid Synthase
T6600	Naftopidil dihydrochloride	KT-611,KT-611 2HCl,Naftopidil DiHCl	5-HT Receptor , Adrenergic Receptor
	Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.		5-HT Receptor , Adrenergic Receptor
T4451	Estramustine phosphate sodium	Ro 21-8837/001,Estramustine phosphate disodium	Apoptosis , Microtubule Associated
	Estramustine phosphate sodium (Ro 21-8837/001) is an antimicrotubule chemotherapy agent; arrests prostate cancer cells in the G2/M phase of the cell cycle.		Apoptosis , Microtubule Associated
T20789	S-23	(S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23	Androgen Receptor
	S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) is an oral selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 increases prostate, seminal ve...		Androgen Receptor
T4102	Goserelin acetate	Fertilan,ICI-118630 acetate,Zoladex	Apoptosis , GNRH Receptor
	Goserelin acetate (Fertilan) is a synthetic long-acting agonist of gonadotropin-releasing hormone, used in treatments of cancer.		Apoptosis , GNRH Receptor

Compounds

Prostate Specific Antigen Substrate

T80552

Synonym:

Target:

prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]

Target: Androgen Receptor

Bicalutamide

T0380

Synonym: ICI-176334

Target: Androgen Receptor, Autophagy

2-hydroxy Flutamide

T7690

Synonym:

Target: Androgen Receptor

Enzalutamide carboxylic acid

T8217

Synonym:

Target: Androgen Receptor, Drug Metabolite

RD162

T21740

Synonym:

Target: Androgen Receptor

Hepln-13

T25492

Synonym: Hepln 13,Hepln13

Target: Androgen Receptor, PROTACs

SK33

T12928

Synonym:

Target: Androgen Receptor

Fatostatin

T9266

Synonym:

Target: Lipid, Fatty Acid Synthase

UT-34

T13273

Synonym:

Target: Androgen Receptor

MI-136

T6889

Synonym:

Target: Apoptosis, Epigenetic Reader Domain, Androgen Receptor

Enzalutamide

T6002

Synonym: MDV3100

Target: Androgen Receptor, Autophagy

AZD3514

T6400

Synonym:

Target: Androgen Receptor

Target: LRRK2, Rho, Ras

Nilutamide

T0272

Synonym: RU23908

Target: Androgen Receptor

Stattic

T6308

Synonym: STAT3 Inhibitor V

Target: Apoptosis, STAT

JNJ-63576253

T9246

Synonym:

Target: Androgen Receptor

PHPS1

T28410

Synonym: PHPS-1,PHPS 1

Target: Epigenetic Reader Domain

OICR-9429

T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

Phenoxodiol

T16522

Synonym: Dehydroequol,Idronoxil,Haginin E

Target: Apoptosis, IAP, Caspase, Topoisomerase, p53

IPI-9119

T36841

Synonym:

Target: Fatty Acid Synthase

Abacavir

T1267

Synonym: Epzicom,Ziagen,Abacavir sulfate

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Andarine

T2108

Synonym: S-4,GTx-007

Target: Androgen Receptor

KGP94

T27730

Synonym: KGP-94,KGP 94

Target: Cysteine Protease

Piclidenoson

T7188

Synonym: CF-101,IB-MECA

Target: Apoptosis, Adenosine Receptor

Dasatinib

T1448

Synonym: BMS-354825

Target: Apoptosis, Bcr-Abl, Src, c-Kit, Autophagy

Naftopidil

T0696

Synonym: KT-611,BM-15275

Target: Adrenergic Receptor

Abacavir sulfate

T6367

Synonym: Abacavir Hemisulfate,1592U89,ABC sulfate,Ziagen

Target: Apoptosis, HIV Protease, Reverse Transcriptase

CLP-3094

T9179

Synonym: 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE

Target: Androgen Receptor

Relugolix

T3630

Synonym: RVT-601,TAK-385

Target: GNRH Receptor

JNJ-63576253 free base

T8933

Synonym: TRC253,JNJ-63576253

Target: Androgen Receptor

Estramustine

T20681

Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,NSC89201,LEO-275

Target: Microtubule Associated

Cyproterone acetate

T1167

Synonym: Androcur,Cyproterone 17-O-acetate

Target: Androgen Receptor

TRPM4-IN-1

T9245

Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid

Target: TRP/TRPV Channel

Dasatinib monohydrate

T1448L

Synonym: BMS-354825 Monohydrate

Target: Apoptosis, Bcr-Abl, Src, c-Kit, Ephrin Receptor, Autophagy

YK-4-279

T2275

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

Fatostatin hydrobromide

T6832

Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

Target: NPC1L1, Fatty Acid Synthase

Naftopidil dihydrochloride

T6600

Synonym: KT-611,KT-611 2HCl,Naftopidil DiHCl

Target: 5-HT Receptor, Adrenergic Receptor

Estramustine phosphate sodium

T4451

Synonym: Ro 21-8837/001,Estramustine phosphate disodium

Target: Apoptosis, Microtubule Associated

S-23

T20789

Synonym: (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23

Target: Androgen Receptor

Goserelin acetate

T4102

Synonym: Fertilan,ICI-118630 acetate,Zoladex

Target: Apoptosis, GNRH Receptor

カタログ番号	製品名	別名	ターゲット
TN7020	Astragenol		Others
	Astragenol is an intermediate for the synthesis of astragenel derivatives. Astragenol derivatives are promising anti-inflammatory drugs in prostate cancer research.		Others
T8188	Podophyllotoxone		Others , Microtubule Associated
	Podophyllotoxinone, a natural compound found in Dysosma versipellis, shows inhibitory activity against L1210 leukemia and KB cells in vitro.		Others , Microtubule Associated
TN2097	Pomolic acid		Apoptosis , Caspase , HIV Protease , AMPK
	Pomolic acid has anti-cancer, anti-inflammatory and apoptotic activities, it can induce apoptosis in SK-OV-3 cells, which is mediated by the mitochondrial-mediated intrinsic and death receptor-induced extrinsic pathways.		Apoptosis , Caspase , HIV Protease , AMPK
T1134	Clofoctol		Antibacterial , Antibiotic
	Clofoctol is a bacteriostatic antibiotic with activity against Gram-positive bacteria, used in the treatment of upper and lower respiratory tract infections.		Antibacterial , Antibiotic
T3324	Lycorine	Galanthidine,Narcissine,Amarylline,Belamarine,Licorine	Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase
	Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive.
T3384	Wedelolactone	IKK Inhibitor II	Apoptosis , NF-κB , Lipoxygenase , Caspase
	Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.		Apoptosis , NF-κB , Lipoxygenase , Caspase
T2939	Forskolin	Coleonol,Colforsin	FXR , Adenylyl cyclase , AChR , Autophagy
	Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM). Forskolin increases cAMP levels, activates PXR and FXR, and induces autophagy. Forskolin produces positive inotropic effects in the...		FXR , Adenylyl cyclase , AChR , Autophagy
T3878	Raddeanin A	NSC382873,Anemodeanin A,Raddeanin R3	Apoptosis , HDAC
	Raddeanin A (NSC-382873) has moderate inhibitory activity against histone deacetylases (HDACs). Raddeanin A has high antiangiogenic potency, antitumor activity.		Apoptosis , HDAC
T6485	Embelin	NSC 91874,Emberine,Embelic acid	Apoptosis , NF-κB , Lipoxygenase , IAP , Prostaglandin Receptor , Autophagy
	Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).
T4S1173	Agrimol B		Sirtuin , PPAR
	1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.		Sirtuin , PPAR
T2S1158	4,5-Dicaffeoylquinic acid	3,4-Dicaffeoylquinic acid,Isochlorogenic acid C	Others , HBV , Endogenous Metabolite
	1. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) has antiviral activity, including anti-HIV-1 integrase activity. 2. 4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) shows anti-hepatotoxic activity.		Others , HBV , Endogenous Metabolite
T6290	Tanespimycin	17-AAG,CP 127374,NSC 330507,KOS 953	Apoptosis , Mitophagy , HSP , Antibacterial , Antibiotic , Autophagy
	Tanespimycin (KOS 953) (17-AAG) is an inhibitor of Hsp90 that selectively inhibits BT474 tumor cell Hsp90 (IC50: 5 nM).
T2S1797	Santalol		Antioxidant , Antifungal
	1. Santalol has good antibacterial, anti-oxidation and anti-tumor activities. 2. α-Santalol is a potent antimitotic agent induced by interference with microtubule assembly. 3. α-Santalol shows a significant antifungal ef...		Antioxidant , Antifungal
T2895	Lupeol	Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol	Apoptosis , Androgen Receptor , Akt
	Lupeol (Monogynol B) is a novel androgen receptor inhibitor with anti-inflammatory and antioxidant activity.		Apoptosis , Androgen Receptor , Akt
T34394	Rotenolone	Rotenolone I,12alpha-HYDROXYROTENONE	Others
	Rotenolone (12alpha-HYDROXYROTENONE) is a metabolite of Rotenone which is a natural compound derived from plants of the genera Derris and Lonchocarpus.		Others
T6S1255	Ophiopogonin-D		ROS
	Ophiopogonin D(OPD) significantly inhibited the in vitro and in vivo growth of prostate cells via RIPK1, OPD may be developed as a potential anti-prostate cancer agent.		ROS
T4869	D-Allose	β-D-Allopyranose,D-(+)-ALLOSE	Others , Endogenous Metabolite
	D-Allose (β-D-Allopyranose) is a rare naturally occurring monosaccharide known to exert anti-proliferative effects on cancer cells. The effects of D-Allose on the cellular membranes of hormone-refractory prostate cancer ...		Others , Endogenous Metabolite
T3329	4',7-Dimethoxyisoflavone	Dimethoxydaidzein,Daidzein dimethyl ether	Endogenous Metabolite , Antifungal
	4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) , a kind of isoflavonoids, showed inhibitory effects on rat prostate testosterone 5α-reductase.		Endogenous Metabolite , Antifungal
TQ0214	Dimethylcurcumin	ASC-J9,GO-Y025	Androgen Receptor
	Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion.		Androgen Receptor
T7873	Iberverin		Others
	Iberverin is a naturan product. It induces phase II enzyme activity and decreases expression of androgen receptors in prostate cancer cells.		Others
T2543	Cabazitaxel	XRP6258,RPR-116258A,TXD 258,taxoid XRP6258	Microtubule Associated , Autophagy
	Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel.		Microtubule Associated , Autophagy
T4767	Formamide	Carbamaldehyde,Methanamide,NSC 748,Formimidic acid	Others , Endogenous Metabolite
	Formamide (NSC-748) is a metabolite used for biological monitoring of workers exposed to N-N-dimethylformamide (DMF). There is a case of significant association between ever having been exposed to DMF and subsequent deve...		Others , Endogenous Metabolite
T13518	5α-Pregnane-3β,6α-diol-20-one		Others
	5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, capable of being synthesized by androgen-responsive prostate cancer cells under conditions of starvation.		Others
T25192	Butyrolactone I	Olomoucin	CDK
	Butyrolactone I (Olomoucin) is an ATP-competitive inhibitor of CDK and cdc2 kinase family. Butyrolactone I shows antitumor effects in non-small cell lung, small cell lung, and prostate cancer cell lines.		CDK
T5646	Cinnamic acid	3-Phenylacrylic acid,β-Phenylacrylic acid	Endogenous Metabolite
	Cinnamic acid (β-Phenylacrylic acid) has potential use in cancer intervention,The concentration causing a 50% reduction of cell proliferation (IC50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung ca...		Endogenous Metabolite
T6S1373	Casticin	Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin	STAT
	1. Casticin (Vitexicarpin) can significantly reduce vascular inflammation, through inhibition of ROS-NF-κB pathway in vascular endothelial cells. 2. Casticin may become a potential leading drug in the therapy of prostate...		STAT
T4S2157	Campesterol	(24R)-5-Ergosten-3β-ol	Endogenous Metabolite
	Campesterol ((24R)-5-Ergosten-3β-ol) is a plant sterol with cholesterol lowering and anticarcinogenic effects, it and other plant sterols often decrease LDL cholesterol levels overall. Campesterol has anti-inflammatory e...		Endogenous Metabolite
T17280	(Z)-Guggulsterone		Apoptosis , VEGFR , Akt
	(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF–VEGF-R2–Akt signaling axis.		Apoptosis , VEGFR , Akt
T14008	2,2,5,7,8-Pentamethyl-6-Chromanol	PMC	Androgen Receptor
	2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) is the anti-oxidant moiety of vitamin E (α-tocopherol), which has potent androgen receptor (AR) signaling modulation and anti-cancer activity against prostate cancer cell lines.		Androgen Receptor
T7990	9-hydroxy-4-androstene-3,17-dione		Others
	9-hydroxy-4-androstene-3,17-dione is a steroid hormone. It has anti-tumor activity and can inhibit the growth of many types of cancer cells, including breast, prostate and lung cancer cells.		Others
TN1805	Isosilybin B		Apoptosis , Androgen Receptor
	Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes to G1-phase blockade and apoptosis.Isosilybin B induces degr...		Apoptosis , Androgen Receptor
T2795	Amygdalin	Laetrile	Others
	Amygdalin (Laetrile) has antifibrotic, antitumor, anti-inflammatory and analgesic effects, amygdalin joint HSYA could inhibit the degeneration of the endplate chondrocytes derived from intervertebral discs of rats induce...		Others
TN1804	Isosilybin A		Apoptosis , Tyrosinase , PPAR , ABC
	Isosilybin A is a partial PPARγ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6μM) and diphenolase (IC50=12.1-44.9μM) of tyrosinase. Isosilybin A shows anti-angio...		Apoptosis , Tyrosinase , PPAR , ABC
T4728	4-Acetamidobutanoic acid	N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID	GABA Receptor , Endogenous Metabolite , Antibacterial
	4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) can be found in blood, feces, and urine, as well as in human prostate tissue. 4-Acetamidobutanoic acid exists in all eukaryotes, ranging from yeast to humans. 4-Acetamid...		GABA Receptor , Endogenous Metabolite , Antibacterial
T5279	Ethylmalonic acid	alpha-Carboxybutyrate,2-Ethylmalonic acid	Others , Endogenous Metabolite
	Ethylmalonic acid (alpha-Carboxybutyrate) can be found in blood, cerebrospinal fluid (CSF), and urine, as well as in human fibroblasts, prostate, and skeletal muscle tissues. Moreover, ethylmalonic acid is found to be as...		Others , Endogenous Metabolite
T3390	Obacunone		Apoptosis , Aromatase , p38 MAPK
	Obacunone has cytotoxicity in androgen-dependent human prostate Y cells. Obacunone exerts an antivirulence effect on S. Typhimurium and may serve as a lead compound for development of antivirulence strategies for S. Typh...		Apoptosis , Aromatase , p38 MAPK
T3S0081	Oxypeucedanin	(+-)-Oxypeucedanin,Oxypeucadanin	Potassium Channel
	1. Oxypeucedanin ((+-)-Oxypeucedanin) has novel anticancer effect, mediated via induction of G2-M cell cycle arrest and apoptosis in human prostate carcinoma DU145 cells. 2. Oxypeucedanin is a kind of open-channel blocke...		Potassium Channel
TMS0418	Dihydroergotoxine mesylate	Ergoloid mesylates	GABA Receptor
	Dihydroergotoxine mesylate (Ergoloid mesylates) is mainly used to improve symptoms and physical symptoms of mental degeneration related to aging.		GABA Receptor
T3851	Vicenin 2	Vicenin -2	RAAS
	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,...		RAAS
T1660	Silibinin	Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species , Autophagy
	Silibinin (Silybin) is the major active constituent of silymarin, a standardized extract of the milk thistle seeds, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silicristin, silidianin an...		Reactive Oxygen Species , Autophagy
T4000	(±)-Equol	Equol,(R,S)-Equol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Drug Metabolite
	(±)-Equol ((R,S)-Equol) is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzen by human intestinal microflora. The estrogen receptor (ER) agonist activity of the naturally occu...
T6S0735	Flavokawain B	Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone	Apoptosis , Others
	1. Flavokawain B (Flavokavain B) has potent anti-inflammatory activity, can significantly inhibit production of NO and PGE2 in LPS-induced RAW 264.7 cells. 2. Flavokawain B, the hepatotoxic constituent from kava root, in...		Apoptosis , Others
TN1013	Cucurbitacin D		Apoptosis
	Cucurbitacin D, a triterpenoid isolated from Ecballium elaterium (L.), exhibits anticancer and antitumor activity, inhibits glucose uptake and lactate production in metastatic PrC, and induces inflammasome activation ind...		Apoptosis
T6491	(-)-(S)-Equol	(−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) is an orally bioavailable, non-steroidal estrogen naturally produced by the metabolism of the isoflavonoid daidzein by human intestinal microflora, with potential chemoprotective a...
T4S2126	Ginkgetin		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
	1. Ginkgetin has anti-influenza virus and anti-fungal activities. 2. Ginkgetin has anti-inflammatory activity, can down-regulates COX-2 induction in vivo against skin inflammatory responses. 3. Ginkgetin is a good STAT3 ...		Apoptosis , Wnt/beta-catenin , COX , STAT , Autophagy
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
TN3941	Ent-17-Hydroxykaur-15-en-19-oic acid		Others
	ent-17-Hydroxykaur-15-en-19-oic acid is a natural compound found in the leaves of the aromatic tree and has an IC50 of 17.63microg/mL on human prostate cells.		Others
TN3416	Angelol M		Others
	Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.		Others
TN5878	7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin
	7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.
T3245L	Carvone	AI3 27596,BRN 1861032,L-Carveol,BRN-1861032,BRN1861032
	Carvone is an agonist of TRPV3 found in spearmint oil. It suppresses cell proliferation in prostate cancer cells and inhibits the growth of Dermatophagoides.
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天然物製品

Target: Others, Microtubule Associated

Pomolic acid

TN2097

Synonym:

Target: Apoptosis, Caspase, HIV Protease, AMPK

Clofoctol

T1134

Synonym:

Target: Antibacterial, Antibiotic

Lycorine

T3324

Synonym: Galanthidine,Narcissine,Amarylline,Belamarine,Licorine

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Wedelolactone

T3384

Synonym: IKK Inhibitor II

Target: Apoptosis, NF-κB, Lipoxygenase, Caspase

Forskolin

T2939

Synonym: Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Raddeanin A

T3878

Synonym: NSC382873,Anemodeanin A,Raddeanin R3

Target: Apoptosis, HDAC

Embelin

T6485

Synonym: NSC 91874,Emberine,Embelic acid

Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy

Agrimol B

T4S1173

Synonym:

Target: Sirtuin, PPAR

4,5-Dicaffeoylquinic acid

T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Tanespimycin

T6290

Synonym: 17-AAG,CP 127374,NSC 330507,KOS 953

Target: Apoptosis, Mitophagy, HSP, Antibacterial, Antibiotic, Autophagy

Santalol

T2S1797

Synonym:

Target: Antioxidant, Antifungal

Lupeol

T2895

Synonym: Fagarasterol,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol

Target: Apoptosis, Androgen Receptor, Akt

Rotenolone

T34394

Synonym: Rotenolone I,12alpha-HYDROXYROTENONE

Synonym: β-D-Allopyranose,D-(+)-ALLOSE

Target: Others, Endogenous Metabolite

4',7-Dimethoxyisoflavone

T3329

Synonym: Dimethoxydaidzein,Daidzein dimethyl ether

Target: Endogenous Metabolite, Antifungal

Dimethylcurcumin

TQ0214

Synonym: ASC-J9,GO-Y025

Target: Androgen Receptor

Synonym: XRP6258,RPR-116258A,TXD 258,taxoid XRP6258

Target: Microtubule Associated, Autophagy

Formamide

T4767

Synonym: Carbamaldehyde,Methanamide,NSC 748,Formimidic acid

Target: Others, Endogenous Metabolite

5α-Pregnane-3β,6α-diol-20-one

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid

Target: Endogenous Metabolite

Casticin

T6S1373

Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin

Target: STAT

Campesterol

T4S2157

Synonym: (24R)-5-Ergosten-3β-ol

Target: Endogenous Metabolite

(Z)-Guggulsterone

T17280

Synonym:

Target: Apoptosis, VEGFR, Akt

2,2,5,7,8-Pentamethyl-6-Chromanol

T14008

Synonym: PMC

Target: Androgen Receptor

9-hydroxy-4-androstene-3,17-dione

Target: Apoptosis, Androgen Receptor

Target: Apoptosis, Tyrosinase, PPAR, ABC

4-Acetamidobutanoic acid

T4728

Synonym: N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID

Target: GABA Receptor, Endogenous Metabolite, Antibacterial

Ethylmalonic acid

T5279

Synonym: alpha-Carboxybutyrate,2-Ethylmalonic acid

Target: Others, Endogenous Metabolite

Obacunone

T3390

Synonym:

Target: Apoptosis, Aromatase, p38 MAPK

Oxypeucedanin

T3S0081

Synonym: (+-)-Oxypeucedanin,Oxypeucadanin

Target: Potassium Channel

Dihydroergotoxine mesylate

TMS0418

Synonym: Ergoloid mesylates

Target: GABA Receptor

Synonym: Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

(±)-Equol

T4000

Synonym: Equol,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Flavokawain B

T6S0735

Synonym: Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone

Target: Apoptosis, Others

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Ginkgetin

T4S2126

Synonym:

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

ent-17-Hydroxykaur-15-en-19-oic acid

7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin

Synonym: AI3 27596,BRN 1861032,L-Carveol,BRN-1861032,BRN1861032

Target:

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00381	PSMA Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
TMPY-06655	PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	HEK293 Cells
	PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 11.64 kDa and the accession number is P57096.
TMPY-06710	PSCA Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	PSCA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.83 kDa and the accession number is P57096.
TMPY-02155	Prostatic Acid Phosphatase Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2.
TMPY-01390	PSMA Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.
TMPY-02672	Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
TMPY-00133	PARM-1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	PARM-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is AAH13294.1.
TMPJ-00654	LGALS8 Protein, Human, Recombinant	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also poss...
TMPY-05269	PSMA Protein, Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is Q04609-1.
TMPY-06960	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 82.72 kDa and the accession number is NP_004467.1.
TMPH-01101	Claudin-3 Protein, Human, Recombinant (Cell-Free, His)	Human	E. coli
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli ex...
TMPH-01103	Claudin-3 Protein-VLP, Human, Recombinant (His)	Human	HEK293 Cells
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian ...
TMPH-01102	Claudin-3 Protein, Human, Recombinant (B2M & His)	Human	E. coli
	Claudin-3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPJ-00278	Clusterin Protein, Human, Recombinant (hFc & His)	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is (33-45) and (60-85) KDa and the accession number is P10909.
TMPJ-00279	Clusterin Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-40 KDa and the accession number is P10909.
TMPY-02258	Kallikrein 3/KLK3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that i...
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin ...
TMPY-03274	CXCL11 Protein, Human, Recombinant	Human	E. coli
	I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low e...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i...
TMPY-05510	BDNF Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. B...
TMPJ-00042	TSLP Protein, Human, Recombinant	Human	E. coli
	Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci...
TMPK-00521	PSMA Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00371	PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated	Mouse	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00370	PSMA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00522	PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated	Cynomolgus	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate...
TMPK-00728	PSCA Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPK-00906	PSCA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell s...
TMPY-04764	PCK2 Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabol...
TMPK-00703	IL-17Rc Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA...
TMPK-01387	EPhA3 Protein, Canine, Recombinant (His)	Canine	HEK293 Cells
	Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude...
TMPJ-00514	ACPP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastas...
TMPJ-01288	KLF6 Protein, Human, Recombinant	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by ...
TMPJ-00891	Kallikrein 2/KLK2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave ...
TMPJ-00733	SPINK1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A dise...
TMPJ-00686	B4GALT3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Beta-1,4-galactosyltransferase 3 (B4GALT3) belongs to the glycosyltransferase 7 family. It is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moie...
TMPJ-01156	PHLDA2 Protein, Human, Recombinant (His)	Human	E. coli
	Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present ...
TMPY-01771	Latexin Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly express...
TMPH-02237	TMPRSS2 Protein, Human, Recombinant (His & Myc)	Human	HEK293 Cells
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPY-03461	GABARAPL2 Protein, Human, Recombinant (His)	Human	E. coli
	GATE-16, also known as ATG8, belongs to the MAP1 LC3 family. It is expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. GATE-16 is expressed at very low levels in lung, thymus and...
TMPK-01375	PRLR Protein, Canine, Recombinant (hFc)	Canine	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPK-00547	PRLR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe ...
TMPH-02236	TMPRSS2 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-...
TMPJ-00482	SEMG1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific a...
TMPY-03867	CBR3 Protein, Human, Recombinant (His)	Human	E. coli
	CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate...
TMPY-04025	CEP57 Protein, Human, Recombinant (GST)	Human	E. coli
	CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between...
TMPJ-00114	EFNA3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle,...
TMPU-00004	STAT5A Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate canc...
TMPJ-00175	B7-H4 Protein, Rhesus macaque, Recombinant (hFc)	Rhesus	HEK293 Cells
	B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negat...
TMPJ-00086	CT-1 Protein, Human, Recombinant (His)	Human	E. coli
	Cardiotrophin-1, also known as CT-1 and CTF1, is a member of the IL-6 superfamily. It is a sreted cytokine that is expressed in heart, skeletal muscle, prostate and ovary, and to lower levels in lung, kidney, pancreas, t...
TMPJ-01058	ARG2 Protein, Human, Recombinant (His)	Human	E. coli
	Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not found...
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PSMA Protein, Human, Recombinant (His)

TMPY-00381

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPY-06655

Species: Mouse

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (His)

TMPY-06710

Species: Mouse

Expression System: HEK293 Cells

Prostatic Acid Phosphatase Protein, Human, Recombinant (His)

TMPY-02155

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Mouse, Recombinant (His)

TMPY-01390

Species: Mouse

Expression System: HEK293 Cells

Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)

TMPY-02672

Species: Mouse

Expression System: HEK293 Cells

PARM-1 Protein, Human, Recombinant (His)

TMPY-00133

Species: Human

Expression System: HEK293 Cells

LGALS8 Protein, Human, Recombinant

TMPJ-00654

Species: Human

Expression System: E. coli

PSMA Protein, Human, Recombinant (His), Biotinylated

TMPY-05269

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06960

Species: Human

Expression System: HEK293 Cells

Claudin-3 Protein, Human, Recombinant (Cell-Free, His)

TMPH-01101

Species: Human

Expression System: E. coli

Claudin-3 Protein-VLP, Human, Recombinant (His)

TMPH-01103

Species: Human

Expression System: HEK293 Cells

Claudin-3 Protein, Human, Recombinant (B2M & His)

TMPH-01102

Species: Human

Expression System: E. coli

Clusterin Protein, Human, Recombinant (hFc & His)

TMPJ-00278

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (His)

TMPJ-00279

Species: Human

Expression System: HEK293 Cells

Kallikrein 3/KLK3 Protein, Human, Recombinant (His)

TMPY-02258

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

CXCL11 Protein, Human, Recombinant

TMPY-03274

Species: Human

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

TMPJ-00662

Species: Human

Expression System: E. coli

BDNF Protein, Mouse, Recombinant (His)

TMPY-05510

Species: Mouse

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant

TMPJ-00042

Species: Human

Expression System: E. coli

PSMA Protein, Cynomolgus, Recombinant (His)

TMPK-00521

Species: Cynomolgus

Expression System: HEK293 Cells

PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

TMPK-00371

Species: Mouse

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (hFc)

TMPK-00370

Species: Human

Expression System: HEK293 Cells

PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

TMPK-00522

Species: Cynomolgus

Expression System: HEK293 Cells

PSCA Protein, Human, Recombinant (hFc)

TMPK-00728

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (hFc)

TMPK-00906

Species: Mouse

Expression System: HEK293 Cells

PCK2 Protein, Human, Recombinant (His & GST)

TMPY-04764

Species: Human

Expression System: Baculovirus Insect Cells

IL-17Rc Protein, Human, Recombinant (hFc)

TMPK-00703

Species: Human

Expression System: HEK293 Cells

EPhA3 Protein, Canine, Recombinant (His)

TMPK-01387

Species: Canine

Expression System: HEK293 Cells

ACPP Protein, Human, Recombinant (His)

TMPJ-00514

Species: Human

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

TMPJ-01288

Species: Human

Expression System: E. coli

Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

TMPJ-00891

Species: Human

Expression System: HEK293 Cells

SPINK1 Protein, Human, Recombinant (His)

TMPJ-00733

Species: Human

Expression System: HEK293 Cells

B4GALT3 Protein, Human, Recombinant (His)

TMPJ-00686

Species: Human

Expression System: HEK293 Cells

PHLDA2 Protein, Human, Recombinant (His)

TMPJ-01156

Species: Human

Expression System: E. coli

Latexin Protein, Mouse, Recombinant (His)

TMPY-01771

Species: Mouse

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (His & Myc)

TMPH-02237

Species: Human

Expression System: HEK293 Cells

GABARAPL2 Protein, Human, Recombinant (His)

TMPY-03461

Species: Human

Expression System: E. coli

PRLR Protein, Canine, Recombinant (hFc)

TMPK-01375

Species: Canine

Expression System: HEK293 Cells

PRLR Protein, Cynomolgus, Recombinant (His)

TMPK-00547

Species: Cynomolgus

Expression System: HEK293 Cells

TMPRSS2 Protein, Human, Recombinant (E. coli, His)

TMPH-02236

Species: Human

Expression System: E. coli

SEMG1 Protein, Human, Recombinant (His)

TMPJ-00482

Species: Human

Expression System: HEK293 Cells

CBR3 Protein, Human, Recombinant (His)

TMPY-03867

Species: Human

Expression System: E. coli

CEP57 Protein, Human, Recombinant (GST)

TMPY-04025

Species: Human

Expression System: E. coli

EFNA3 Protein, Mouse, Recombinant (hFc)

TMPJ-00114

Species: Mouse

Expression System: HEK293 Cells

STAT5A Protein, Human, Recombinant (His)

TMPU-00004

Species: Human

Expression System: E. coli

B7-H4 Protein, Rhesus macaque, Recombinant (hFc)

TMPJ-00175

Species: Rhesus

Expression System: HEK293 Cells

CT-1 Protein, Human, Recombinant (His)

TMPJ-00086

Species: Human

Expression System: E. coli

ARG2 Protein, Human, Recombinant (His)

TMPJ-01058

Species: Human

Expression System: E. coli

--------- More ---------

カタログ番号	製品名
L2195	Anti-Prostate Cancer Compound Library	2070 compounds
	2070 compounds associated with prostate cancer that can be used for high-throughput and high-content screening.
L4300	Wnt/Hedgehog/Notch Compound Library	237 compounds
	A unique collection of 237 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening;
L2192	Anti-Pancreatic Cancer Compound Library	2238 compounds
	A unique collection of 2238 pancreatic cancer related compounds can be used in HTS and HCS;
L8710	Cuproptosis Compound Library	400 compounds
	TargetMol’s Cuproptosis Compound Library is a collection of 400 compounds related to copper-dependent death that can be used to study its mechanism and related diseases.

ライブラリー

Anti-Prostate Cancer Compound Library

L2195

Compounds: 2070

Wnt/Hedgehog/Notch Compound Library

L4300

Compounds: 237

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2238

Cuproptosis Compound Library

L8710

Compounds: 400