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Search Results for " cytokines "

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Others

115

阻害剤

天然化合物

136

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T21729	(±)-Lisofylline		Others
	(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.		Others
T38361	GSK717		IL Receptor , NOD
	GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...		IL Receptor , NOD
T8233	BRD3308		Apoptosis , HIV Protease , HDAC
	BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.		Apoptosis , HIV Protease , HDAC
T6716	Valsartan	Diovan,Tareg,CGP 48933	RAAS
	Valsartan (CGP 48933) is a tetrazole derivative and angiotensin II type 1 receptor blocker that is used to treat hypertension.		RAAS
T21445	Naphazoline	AK-Con,Naphcon-a,Clear Eyes,All Clear	Adrenergic Receptor
	Naphazoline (Naphcon-a) is a sympathomimetic compound with marked alpha adrenergic activity. Naphazoline can be used as a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane.		Adrenergic Receptor
T0446	Naphazoline hydrochloride	Albalon,Rhinantin,Naphazoline HCl	Adrenergic Receptor
	Naphazoline hydrochloride (Naphazoline HCl) is an adrenergic vasoconstrictor agent used as a decongestant.		Adrenergic Receptor
T2036	6-OAU	GTPL5846	GPR
	6-OAU (GTPL5846)(GTPL5846; 6-n-octylaminouracil) is a surrogate agonist of GPR84; activates human GPR84 in the presence of Gqi5 chimera in HEK293 cells with an EC50 of 105 nM in the PI assay.		GPR
T38423	CL097	CL097	Reactive Oxygen Species , TLR
	CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production.		Reactive Oxygen Species , TLR
T4982	Benznidazol	Radanil,Benznidazole,Ro 71051,Ro 07-1051	Antibiotic , Parasite
	Benznidazol (Benznidazole)e has an antiprotozoal activity by interfering with parasite protein biosynthesis, influencing cytokines production and stimulating host phagocytosis.		Antibiotic , Parasite
T27034	CL075	3M002,CL-075	NF-κB , TLR , MyD88
	CL075 (3M002) is a selective TLR8 agonist.CL075 has immunomodulatory activity by triggering the MyD88-dependent signaling pathway, activating NF-κB and IRF7 to elicit the production of inflammatory cytokines and type I i...		NF-κB , TLR , MyD88
T7872	Monolaurin		Others
	Monolaurin is a surfactant and emulsifer found in coconut oil. It inhibitis growth of Staphylococcus, Streptococcus, Gardnerella, Candida, and Haemophilus, and decreases production of pro-inflammatory cytokines.		Others
T15096	Delgocitinib	JTE-052,Corectim（Delgocitinib）	Tyrosine Kinases , JAK
	Delgocitinib (JTE-052) is a specific JAK (Janus kinase) inhibitor with IC50 values of 2.8, 2.6, 13, and 58 nM for JAK1, JAK2, JAK3, and Tyk2 respectively. Delgocitinib is involved in various inflammatory and autoimmune d...		Tyrosine Kinases , JAK
T20763	Betamethasone disodium phosphate	Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616	Others
	Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a corticosteroid with anti-inflammatory activity that promotes the polarization of M1 to M2 macrophages by decreasing the secretion of pro-in...		Others
T33535	MW01-2-151SRM	MW 151,MW-151,MW012151SRM,MW151,MW01 2 151SRM	Others
	MW01-2-151SRM is a novel small molecule inhibitor of microglia activation that crosses the blood-brain barrier, has anti-neuroinflammatory effects, attenuates the up-regulation of glial cytokines in models of neuroinflam...		Others
T9543	Syk Inhibitor II hydrochloride		Others
	The impact of spleen tyrosine kinase (Syk) signaling might be prominent in lupus because (i) Syk is a shared downstream signaling molecule among circulating immune complex, LPS, and (1→3)-β-D-glucan (BG), and (ii) all of...		Others
T6914	Oclacitinib maleate	PF-03394197 maleate,PF-03394197	Tyrosine Kinases , JAK
	Oclacitinib maleate (PF-03394197 maleate) is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 3...		Tyrosine Kinases , JAK
T6964	Resiquimod	R848,S28463	HCV Protease , TLR
	Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and acti...		HCV Protease , TLR
T36310	AKT-IN-6	INCB-047775	Akt
	AKT-IN-6 (INCB-047775) has an inhibitory effect on ATK. Akt is an important component of cellular signaling for growth factors, cytokines, and other cell stimuli. Abnormal Akt activation has been associated with the deve...		Akt
T30231	AVP-13358		Others
	AVP-13358 is a CD23 antagonist (immunoglobulin ε-Fc receptor antagonist), an immunoglobulin E inhibitor. AVP-13358 has potent activity against IgE, cytokines and CD23 and is used in the treatment of immune system disorde...		Others
T2401	Alogliptin Benzoate	SYR 322,Alogliptin(SYR-322)benzoate	Ferroptosis , Proteasome , DPP-4
	Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may inhibit inflammatory responses by preventing the...		Ferroptosis , Proteasome , DPP-4
T6273	Vadimezan	DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404	Influenza Virus , VDA , STING , IFNAR
	Vadimezan (DMXAA) is a vascular disrupting agent, a murine STING agonist, and an inducer of cytokines such as type I IFN. Vadimezan has antitumor activity and induces a rapid cessation of blood flow in tumors without aff...		Influenza Virus , VDA , STING , IFNAR
T79600	Zharp2-1		RIP kinase
	Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for ...		RIP kinase
TP1592L	C-Reactive Protein (CRP) 174-185 acetate	C-Reactive Protein (CRP) 174-185 acetate(160369-86-8 free base)	Others
	C-Reactive Protein (CRP) 174-185 acetate is an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) (RS-83277) shows similar activ...		Others
T67896	CB2R/FAAH modulator-1		Cannabinoid Receptor , FAAH
	CB2R/FAAH modulator-1, a cannabinoid type 2 receptor (CB2R) agonist, is also a fatty acid amide hydrolase (FAAH) inhibitor (IC50=4 μM) that reduces the production of pro-inflammatory and anti-inflammatory cytokines and i...		Cannabinoid Receptor , FAAH
T38362	Guselkumab	CNTO 1959	IL Receptor
	Guselkumab (CNTO 1959) is a recombinant human IgG1 monoclonal antibody targeting the IL-23p19 subunit. Guselkumab binds to human cynomolgus monkey IL-23 with Kd values of 3.3 and 1.9 pmol/L, respectively. Guselkumab can ...		IL Receptor
T0468	Lidocaine	Lignocaine,Alphacaine,Xylocaine	Apoptosis , ERK , NF-κB , MEK , Sodium Channel , Histamine Receptor
	Lidocaine (Alphacaine) is an amide local anesthetic with anti-inflammatory properties in vitro and in vivo. It has this functions perhaps due to an attenuation of intracellular adhesion molecule-1 (ICAM-1), pro-inflammat...
T76781	Itolizumab	EQ-001	Others
	Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti...		Others
T67924	ABzOH
	ABzOH is a benzoic acid derivative, similar in structure to non-steroidal anti-inflammatory drugs such as aspirin, with anti-inflammatory, anti-tumor and anti-proliferative effects. ABzOH can not only inhibit the express...
T15017	CU-T12-9		TLR
	CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines, and enhancing TLR1 and TLR2 dimerization.CU-T12-9 activat...		TLR
T61025	GSK-1482160		P2X Receptor
	GSK-1482160 is a CNS-penetrant negative allosteric modulator of P2X7 receptor with oral activity. The P2X7 receptor is involved in the production of pro-inflammatory cytokines by central and peripheral immune cells, so G...		P2X Receptor
T12848	SB-657510		Others , Neurotensin Receptor
	SB-657510 is a urotensin II (UII) receptor (UT) antagonist. The Ki values of UT for human, monkey, cat, rat and mouse were 61, 17, 30, 65 and 56 nM, respectively. SB-657510 plays an anti-inflammatory role by inhibiting U...		Others , Neurotensin Receptor
T2548	Diflorasone		Glucocorticoid Receptor
	Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...		Glucocorticoid Receptor
T41142	EM 163		IL Receptor , p38 MAPK , MyD88
	EM 163 is a TIR-TIR interaction inhibitor, which is a TIR (Toll/interleukin-1 receptor) structural domain mimic of the MyD88 protein. EM 163 targets the TIR structural domain in the IL-1 receptor and blocks the interacti...		IL Receptor , p38 MAPK , MyD88
T25453	Glaspimod	F 107647,SK&,F-107647,F107647
	Glaspimod is a synthetic hematoregulatory peptide. It shares biological and/or modulatory activities with natural hematopoetic cytokines.
T31018	CP 115953	CP115953,Cp-115,953,CP-115953
	CP 115953 stimulated the production of cytokines by lymphocytes. CP 115953 inhibits the activity of topoisomerase II by interacting with the enzyme.
T70484	AD-35
	AD-35 is a neuroprotectant for treating Alzheimer’s diseases by significantly inhibiting the production and release of proinflammatory cytokines TNF-α and IL-1β.
T16570	Pralnacasan	VX-740,HMR 3480	Others
	Pralnacasan inhibits proinflammatory cytokines IL-18, IL-1β , and IFN-γ. Pralnacasan is an effective, non-peptide, and orally active interleukin-1β converting enzyme inhibitor (Ki: 1.4 nM). Pralnacasan has the potential ...		Others
T71814	ST026567
	ST026567 is a potent mast cell (MC) activator which promotes de novo synthesis of cytokines and induces the release of eicosanoids from human and mouse MCs.
T10366	Arg-Gly-Asp-Ser	Fibronectin tetrapeptide,RGDS peptide	Others
	Arg-Gly-Asp-Ser is an integrin-binding sequence that inhibits integrin receptor function. It decreases systemic inflammation via inhibition of collagen-triggered activation of leukocytes and attenuates expression of infl...		Others
T30831	Cgp 43182	Cgp-43182,Cgp43182
	CGP 43182 is an effective inhibitor of group IIA secretory phospholipase A2 (Group IIA sPLA2) activity in vitro, which can be used to prevent the synergistic effect of pro-inflammatory genes stimulated by cytokines media...
T71711	ST029248
	ST029248 is a potent mast cell (MC) activator, promoting de novo synthesis of cytokines and inducing the release of eicosanoids from human and mouse MCs.
T7503L	Upadacitinib tartrate	ABT 494,ABT-494,ABT494
	Upadacitinib is a potent and selective JAK inhibitor. Upadacitinib is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. Upadacitinib demonstrates efficacy in...
TP2035	FSL-1	FSL 1
	TLR2/6 agonist (also a putative TLR10 ligand). Activates NF-κB. Induces pro-inflammatory cytokines including IL-8, IL-1β, CCL20 and TNF-α in vitro. Synergizes with IFNγ to induce CXCL10 release from melanoma cells.
T70001	Pyrazinib
	Pyrazinib is a novel inhibitor of angiogenesis and metabolism of oesophageal adenocarcinoma (oac) radioresistance, significantly inhibiting the secretion of il-6, il-4, il-8 and il-13 cytokines from in oac radioresist...
T73326	CB2R-IN-3
	CB2R-IN-3 is a selective antagonist of cannabinoid type 2 receptor (CB2R) . CB2R-IN-3 has high affinity for human CB2R and specific selectivity for CB1R. CB2R-IN-3 can be combined with CB65 , the activator of CB2R. CB2R-...
TP1592	C-Reactive Protein (CRP) (174-185)	C-Reactive Protein (CRP) 174-185
	CRP, an acute phase serum protein synthesized in response to inflammatory cytokines, produces antitumor effects in animals. The fragment CRP (174-185) (RS-83277) shows similar activity by significantly enhancing the tumo...
T72223	Anti-inflammatory agent 7
	Anti-inflammatory Agent 7 suppresses proinflammatory cytokines by hindering the NF-κB/MAPK signaling pathway in both LPS-treated RAW 264.7 cells and mice.
T70367	SNU-BP
	SNU-BP is an agonist of PPAR-gamma, inhibiting lipopolysaccharide (LPS)-induced NO production and pro-inflammatory cytokines. SNU-BP potentiates interleukin-4-induced arginase-1 expression, and promotes microglial polari...
T70015	GSK563
	GSK563 is a potent GVIA iPLA2 inhibitor (XI(50) 0.0000021, IC50 1 nM). GSK563 is 22 000 times more active against GVIA iPLA2 than GIVA cPLA2. It was found to reduce β-cell apoptosis induced by proinflammatory cytokines,...
T39778	Influenza A virus-IN-1
	Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV re...

Compounds

Target: IL Receptor, NOD

BRD3308

T8233

Synonym:

Target: Apoptosis, HIV Protease, HDAC

Valsartan

T6716

Synonym: Diovan,Tareg,CGP 48933

Target: RAAS

Naphazoline

T21445

Synonym: AK-Con,Naphcon-a,Clear Eyes,All Clear

Target: Adrenergic Receptor

Naphazoline hydrochloride

T0446

Synonym: Albalon,Rhinantin,Naphazoline HCl

Target: Adrenergic Receptor

Target: Reactive Oxygen Species, TLR

Benznidazol

T4982

Synonym: Radanil,Benznidazole,Ro 71051,Ro 07-1051

Target: Antibiotic, Parasite

CL075

T27034

Synonym: 3M002,CL-075

Target: NF-κB, TLR, MyD88

Synonym: JTE-052,Corectim（Delgocitinib）

Target: Tyrosine Kinases, JAK

Betamethasone disodium phosphate

T20763

Synonym: Vista-Methasone,NSC90616,Betamethasone 21-phosphate disodium salt,NSC-90616

Target: Others

MW01-2-151SRM

T33535

Synonym: MW 151,MW-151,MW012151SRM,MW151,MW01 2 151SRM

Target: Others

Syk Inhibitor II hydrochloride

Synonym: PF-03394197 maleate,PF-03394197

Target: Tyrosine Kinases, JAK

Resiquimod

T6964

Synonym: R848,S28463

Target: HCV Protease, TLR

Synonym: SYR 322,Alogliptin(SYR-322)benzoate

Target: Ferroptosis, Proteasome, DPP-4

Vadimezan

T6273

Synonym: DMXAA,5,6-Dimethylxanthenone-4-acetic Acid,NSC 640488,ASA-404

Target: Influenza Virus, VDA, STING, IFNAR

C-Reactive Protein (CRP) 174-185 acetate

TP1592L

Synonym: C-Reactive Protein (CRP) 174-185 acetate(160369-86-8 free base)

Target: Others

CB2R/FAAH modulator-1

T67896

Synonym:

Target: Cannabinoid Receptor, FAAH

Synonym: Lignocaine,Alphacaine,Xylocaine

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel, Histamine Receptor

Target: Others, Neurotensin Receptor

Diflorasone

T2548

Synonym:

Target: Glucocorticoid Receptor

EM 163

T41142

Synonym:

Target: IL Receptor, p38 MAPK, MyD88

Glaspimod

T25453

Synonym: F 107647,SK&,F-107647,F107647

Target:

CP 115953

T31018

Synonym: CP115953,Cp-115,953,CP-115953

Synonym: VX-740,HMR 3480

Synonym: Fibronectin tetrapeptide,RGDS peptide

Target: Others

Cgp 43182

T30831

Synonym: Cgp-43182,Cgp43182

Upadacitinib tartrate

T7503L

Synonym: ABT 494,ABT-494,ABT494

C-Reactive Protein (CRP) (174-185)

TP1592

Synonym: C-Reactive Protein (CRP) 174-185

Target:

Anti-inflammatory agent 7

Influenza A virus-IN-1

T39778

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T3S2312	Poncirin	Isosakuranetin-7-neohesperidoside	Apoptosis , Others
	1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...		Apoptosis , Others
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
T9862	Pseudocoptisine chloride	Isocoptisine chloride	AChE
	Pseudocoptisine chloride (Isocoptisine chloride) is isolated from Corydalis Tuber with anti-inflammatory and anti-amnestic properties. Pseudocoptisine chloride inhibits acetylcholinesterase (AChE) activity (IC50 = 12.8 μ...		AChE
TN6796	2'-FUCOSYLLACTOSE	2'-Fucosyl-D-lactose	Others
	2'-FUCOSYLLACTOSE (2'-Fucosyl-D-lactose) is a fucose-containing oligosaccharide.		Others
TN6722	Terminolic acid	2α,6β,23-trihydroxyl oleanolic acid	Antibacterial
	Terminolic acid (2α,6β,23-trihydroxyl oleanolic acid) is a pentacyclic triterpenoid glucoside isolated from Combretum racemosum, can inhibit the pro-inflammatory cytokines by binding to receptor active site of IL-1β and ...		Antibacterial
TN1291	7,3',4'-Tri-O-methylluteolin	5-Hydroxy-3',4',7-trimethoxyflavone	TNF , COX , Interleukin
	7,3',4'-Tri-O-methylluteolin (5-Hydroxy-3',4',7-trimethoxyflavone) has anti-inflammatory, antibacterial and antifungal activities, it also shows moderate antitrypanosomal activity with MIC value of 19.0 ug/ml		TNF , COX , Interleukin
T14149	AICAR phosphate	AICA Riboside phosphate,Acadesine phosphate	Mitophagy , NOS , YAP , AMPK
	AICAR phosphate (Acadesine phosphate) is an AMPK activator and inhibitor of autophagy, YAP, and mitophagy, as well as an adenosine analog that regulates glucose and lipid metabolism, and inhibits the production of pro-in...		Mitophagy , NOS , YAP , AMPK
T10689	Cauloside D		Others
	Cauloside D, a triterpene glycoside isolated from Caulophyllum robustum Max, inhibits the expression of iNOS and proinflammatory cytokines with anti-inflammatory effects.		Others
T34295	Resiniferatoxin	RTX,[3H]resiniferatoxin	IL Receptor
	Resiniferatoxin ([3H]resiniferatoxin) inhibits the production of Th1 cytokines, contributing to the defense against T. spiralis infection, and can be used in studies about the modulator of the immune response.		IL Receptor
T6S0107	Peimine	Wanpeinine A,Dihydroisoimperialine,Verticine	Others
	1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.		Others
T5660	Menthone		IL Receptor , TNF , NF-κB , Parasite
	Menthone has anti-inflammary activity,, it can suppress the lipopolysaccharide (LPS)-induced proinflammatory cytokines, interleukin-1beta (IL-1beta) and tumor necrosis factor-alpha (TNF-alpha),as well as nuclear factor k...		IL Receptor , TNF , NF-κB , Parasite
T3826	Polygalasaponin F		NF-κB , TLR , Akt , PI3K
	Polygalasaponin F has anti-neuroinflammatory activity, can inhibit the release of inflammatory cytokines TNF-α and NO induced by lipopolysaccharides (LPS) and reduce the expression of inducible nitric oxide synthases. Po...		NF-κB , TLR , Akt , PI3K
TN1410	Asperulosidic acid	ASPA	ERK , NF-κB
	Asperulosidic acid (ASPA) has anti-tumor, anti-oxidant, and anti-inflammatory activities. ASPA is related to the inhibition of inflammatory cytokines (TNF-α, IL-6) and mediators via suppression of the NF-κB and mitogen-a...		ERK , NF-κB
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
TN2091	Polygalacin D		Apoptosis , IAP
	Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...		Apoptosis , IAP
T5S0167	Atractylenolide I		IL Receptor , TNF , TLR , JAK , STAT
	1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide...		IL Receptor , TNF , TLR , JAK , STAT
T3426	Bacoside A		MMP , Others , TNF , Dopamine Receptor , NOS , ROS
	Bacoside A has a possible anticancer activity that could be inducing cell cycle arrest and apoptosis through Notch pathway in GBM in vitro. It exerts cytoprotective efficacy by attenuation of ROS generated through oxidat...		MMP , Others , TNF , Dopamine Receptor , NOS , ROS
T5S1895	Norisoboldine	Laurelliptine,(+)-Laurelliptine	MAPK , Adenosine Receptor
	1. Norisoboldine ((+)-Laurelliptine) might be a potential therapeutic agent for rheumatoid arthritis, and it functions through protecting joint destruction as well as regulating the abnormal immune responses. 2. Norisobo...		MAPK , Adenosine Receptor
T2S2173	(E)-Naringenin chalcone	Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone	Others
	Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha...		Others
T2S2362	Dehydrocorydaline nitrate		BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T6S0139	Neobavaisoflavone		Apoptosis , DNA/RNA Synthesis
	1. Neobavaisoflavone is isolated as a DNA polymerase inhibitor. 2. Neobavaisoflavone might be a potential anabolic agent to treat bone loss-associated diseases. 3. Neobavaisoflavone has anti-inflammatory activity, can si...		Apoptosis , DNA/RNA Synthesis
TN1448	(-)-Bornyl acetate	L-(-)-Bornyl acetate,Bornyl acetate	p38 MAPK , NF-κB , JNK , Antifungal
	(-)-Bornyl acetate (L-(-)-Bornyl acetate) is a less active enantiomer of (+)-Bornyl acetate. (-)-Bornyl acetate isolates from hyssop oil and possesses antifungal activity. (-)-Bornyl acetate shows highly active whitening...		p38 MAPK , NF-κB , JNK , Antifungal
T3779	Crocin II	Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B	Caspase , COX , NO Synthase
	Crocin II (Crocetin gentiobiosylglucosyl ester) has anti-inflammatory and anti-apoptotic effects against gastric ischemia-reperfusion injury in rats, the effect of crocin is mainly mediated by reducing the protein expres...		Caspase , COX , NO Synthase
T5S0045	Isofraxidin	6,8-Dimethoxyumbelliferone,Phytodolor	MMP , ERK , p38 MAPK , TLR , COX
	1. Isofraxidin (Phytodolor) protects leukemia cells from radiation-induced apoptosis via ROS/mitochondria pathway in a p53-independent manner. 2. Isofraxidin has a protective effect against LPS-induced ALI, and the prote...		MMP , ERK , p38 MAPK , TLR , COX
T4S0878	Prunetin	Prunusetin	ERK , Dehydrogenase , NF-κB
	1. Prunetin (Prunusetin) significantly reduces serum levels of inflammatory cytokines and mortality in mice challenged with lipopolysaccharide. 2. Prunetin mediates anti-obesity/adipogenesis effects by suppressing obesit...		ERK , Dehydrogenase , NF-κB
T9113	Myristicin	Myristicine	IL Receptor , Anti-infection , BCL , P450 , PARP , 5-HT Receptor , Caspase , GABA Receptor , NO Synthase
	Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with ...
T3877	Esculentoside A		NF-κB , COX
	Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...		NF-κB , COX
TN1831	Macranthoside A	Kalopanaxsaponin H	Antioxidant
	Macranthoside A (Kalopanaxsaponin H) is a triterpenoid glycoside extracted from rehmannia and belongs to the iridoterpenoid synthesis. Macranthoside A has anti-inflammatory, antioxidant, antibacterial and neuroprotective...		Antioxidant
T2S2264	Linalool	Linalol,(±)-Linalool,Phantol	Apoptosis , IL Receptor , TNF , Endogenous Metabolite , iGluR
	1. Linalool (Linalol), a natural compound of the essential oils, has been shown to have antinociceptive, antimicrobial, and anti-inflammatory properties. 2. Linalool was protected against LPS/GalN-induced liver injury th...
T2563	Acetyl-L-carnitine hydrochloride	Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride	Others , Endogenous Metabolite
	Acetyl-L-carnitine hydrochloride (Acetyl L-carnitine hydrochloride) is a nutritional supplement composed of the hydrochloride salt form of the acetylated form of the endogenously produced L-carnitine, with potential neur...		Others , Endogenous Metabolite
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T3S2259	Methyl eugenol	4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether	GABA Receptor
	1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its...		GABA Receptor
T6677	Sophocarpine		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
	Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.		ERK , p38 MAPK , NF-κB , TLR , COX , HER , JNK , STAT
TN6566	Licoflavanone
	Licoflavanone exhibits antioxidant and anti-inflammatory activities,it markedly decreases pro-inflammatory cytokines and cyclooxygenase 2/inducible nitric oxide synthase (COX-2/iNOS) expression levels.
TMA2576	Episappanol		IL Receptor , TNF
	Episappanol has anti-inflammatory activity , it can significantly inhibit the secretion of the pro-inflammatory cytokines interleukin (IL-6) and tumor necrosis factor-alpha (TNF-α).		IL Receptor , TNF
TN1504	Citreorosein		cAMP , NF-κB , PI3K
	Citreorosein is a cAMP phosphodiesterase inhibitor, it has anti-inflammatory effect, inhibits proinflammatory cytokines production through the inhibition of both MAPKs and AKT-mediated IκB kinase (IKK) phosphorylation an...		cAMP , NF-κB , PI3K
TN4013	Esculentic acid		IL Receptor , TNF , COX
	Esculentic acid has anti-inflammatory effect, it has protective effects against LPS-induced endotoxic shock may be mediated, at least in part, by regulation the release of inflammatory cytokines and mediators, and protei...		IL Receptor , TNF , COX
TN1485	Chicanine		Others , NF-κB , Prostaglandin Receptor
	Chicanine has anti-inflammatory activity in macrophages by down-regulating LPS-induced inflammatory cytokines in IκBα±/MAPK/ERK signaling pathways.		Others , NF-κB , Prostaglandin Receptor
T14877	Cauloside C		Others
	Cauloside C, a triterpene glycoside isolated from Caulophyllum robustum Max, exerts anti-inflammatory effects through the inhibition of expression of iNOS and proinflammatory cytokines.		Others
T38838	QS-21	Stimulon,QS-21
	QS-21, an immunostimulatory saponin, is a powerful vaccine adjuvant that stimulates both Th2 humoral and Th1 cell-mediated immune responses by interacting with antigen presenting cells (APCs) and T cells. Additionally, Q...
TN6366	Lupinalbin A
	Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokine...
T5S0313	Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside	Liquiritin apioside	Others , TNF
	Liquiritin apioside has antioxidant property by inducing glutathione (GSH) biosynthesis via the inhibition of cytokines and protected lung epithelial cells against cigarette smoke-mediated oxidative stress, might be as p...		Others , TNF
TN4879	Questinol		IL Receptor , TNF , COX , Prostaglandin Receptor
	Questinol exhibits significant anti-obesity activity. It shows anti-inflammatory effect in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells, it can inhibit the production of pro-inflammatory cytokines, including TNF-α...		IL Receptor , TNF , COX , Prostaglandin Receptor
TN5149	Tirotundin		NF-κB , COX , PPAR
	Tirotundin is a PPARα/γ dual agonist, it exerts anti-diabetic effect through PPARγ pathway. It shows anti-inflammatory activity, it inhibits inhibit the activation of NF-kappa B, thereby, the synthesis of inflammatory me...		NF-κB , COX , PPAR
T81408	Preleoheterin
	Preleoheterin (Compound 3), a labdane diterpene isolated from L. japonicus [1], exhibits anti-inflammatory properties by inhibiting the production of nitric oxide and pro-inflammatory cytokines in LPS-activated macrophag...
T26545	Acanthoic acid	NP1302,NP 1302: NP-1302
	Acanthoic acid is a pimaradiene diterpene isolated from Acanthopanax koreanum with anti-inflammatory activities. Acanthoic acid downregulates LPS-induced IL-1β, IL-6 and TNF-α production in BALF, attenuates lung histopat...
T38394	PSMα3
	PSMα3 is a peptide compound that can be utilized to induce tolerance in dendritic cells (DCs) for DC vaccination strategies. It effectively penetrates and modulates human monocyte-derived DCs by modifying the maturation ...
TN5474	Bonducellin
	Bonducellin has anti-inflammatory activities, it can significantly and dose-dependently inhibit the inflammatory mediators; nitric oxide (NO), and cytokines [tumor necrosis factor (TNF)-alpha and interleukin (IL)-12. Bon...
T79970	Taxamairin B
	Taxamairin B is a potent anti-inflammatory compound that inhibits the expression of proinflammatory cytokines (TNF-α, IL-1β, and IL-6) and reduces the production of NO and ROS in LPS-induced RAW264.7 cells. Furthermore, ...
TN2243	Sugiol	10-Deoxoxanthoperol	IL Receptor , TNF , ROS
	Sugiol (10-Deoxoxanthoperol) has antioxidant efficacy, it has significant scavenging activities of 1,1-diphenyl-2-picryl hydrazyl, nitric oxide, superoxide and hydroxyl free radicals. Sugiol's efficacy in inhibiting the ...		IL Receptor , TNF , ROS
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天然物製品

Poncirin

T3S2312

Synonym: Isosakuranetin-7-neohesperidoside

Target: Apoptosis, Others

Gypenoside L

TN1721

Synonym:

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Pseudocoptisine chloride

T9862

Synonym: Isocoptisine chloride

Target: AChE

2'-FUCOSYLLACTOSE

TN6796

Synonym: 2'-Fucosyl-D-lactose

Target: Others

Terminolic acid

TN6722

Synonym: 2α,6β,23-trihydroxyl oleanolic acid

Target: Antibacterial

7,3',4'-Tri-O-methylluteolin

TN1291

Synonym: 5-Hydroxy-3',4',7-trimethoxyflavone

Target: TNF, COX, Interleukin

AICAR phosphate

T14149

Synonym: AICA Riboside phosphate,Acadesine phosphate

Target: Mitophagy, NOS, YAP, AMPK

Synonym: RTX,[3H]resiniferatoxin

Target: IL Receptor

Peimine

T6S0107

Synonym: Wanpeinine A,Dihydroisoimperialine,Verticine

Target: IL Receptor, TNF, NF-κB, Parasite

Polygalasaponin F

T3826

Synonym:

Target: NF-κB, TLR, Akt, PI3K

Target: Others, IFNAR, Interleukin

Polygalacin D

TN2091

Synonym:

Target: Apoptosis, IAP

Atractylenolide I

T5S0167

Synonym:

Target: IL Receptor, TNF, TLR, JAK, STAT

Bacoside A

T3426

Synonym:

Target: MMP, Others, TNF, Dopamine Receptor, NOS, ROS

Norisoboldine

T5S1895

Synonym: Laurelliptine,(+)-Laurelliptine

Target: MAPK, Adenosine Receptor

(E)-Naringenin chalcone

T2S2173

Synonym: Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone

Target: Others

Dehydrocorydaline nitrate

T2S2362

Synonym:

Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy

Neobavaisoflavone

T6S0139

Synonym:

Target: Apoptosis, DNA/RNA Synthesis

(-)-Bornyl acetate

TN1448

Synonym: L-(-)-Bornyl acetate,Bornyl acetate

Target: p38 MAPK, NF-κB, JNK, Antifungal

Crocin II

T3779

Synonym: Crocin 2,Crocetin gentiobiosylglucosyl ester,Tricrocin,Crocin B

Target: Caspase, COX, NO Synthase

Isofraxidin

T5S0045

Synonym: 6,8-Dimethoxyumbelliferone,Phytodolor

Target: MMP, ERK, p38 MAPK, TLR, COX

Prunetin

T4S0878

Synonym: Prunusetin

Target: ERK, Dehydrogenase, NF-κB

Myristicin

T9113

Synonym: Myristicine

Target: IL Receptor, Anti-infection, BCL, P450, PARP, 5-HT Receptor, Caspase, GABA Receptor, NO Synthase

Synonym: Kalopanaxsaponin H

Target: Antioxidant

Linalool

T2S2264

Synonym: Linalol,(±)-Linalool,Phantol

Target: Apoptosis, IL Receptor, TNF, Endogenous Metabolite, iGluR

Acetyl-L-carnitine hydrochloride

T2563

Synonym: Acetyl L-carnitine hydrochloride,O-Acetylcarnitine,O-acetyl-L-carnitine,O-Acetyl-L-carnitine hydrochloride

Target: Others, Endogenous Metabolite

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Methyl eugenol

T3S2259

Synonym: 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether

Target: GABA Receptor

Sophocarpine

T6677

Synonym:

Target: ERK, p38 MAPK, NF-κB, TLR, COX, HER, JNK, STAT

Target: IL Receptor, TNF

Citreorosein

TN1504

Synonym:

Target: cAMP, NF-κB, PI3K

Esculentic acid

TN4013

Synonym:

Target: IL Receptor, TNF, COX

Chicanine

TN1485

Synonym:

Target: Others, NF-κB, Prostaglandin Receptor

Synonym: Stimulon,QS-21

Liguiritigenin-7-O-D-apiosyl-4'-O-D-glucoside

T5S0313

Synonym: Liquiritin apioside

Target: IL Receptor, TNF, COX, Prostaglandin Receptor

Tirotundin

TN5149

Synonym:

Target: NF-κB, COX, PPAR

Synonym: NP1302,NP 1302: NP-1302

Synonym: 10-Deoxoxanthoperol

Target: IL Receptor, TNF, ROS

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPJ-01210	IL-33 Protein, Mouse, Recombinant	Mouse	E. coli
	Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi...
TMPK-00114	C-Reactive Protein /CRP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPJ-00327	M-CSF/CSF1 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and th...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPY-02904	TLR4 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans...
TMPJ-01461	IL-15RA & IL-15 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f...
TMPJ-01462	IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)	Human	HEK293 Cells
	IL15RA is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction. It can signal both in cis and trans where IL15R f...
TMPK-00646	Gp130/IL6ST Protein, Rhesus macaque, Recombinant (His)	Rhesus	HEK293 Cells
	gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic fa...
TMPK-01029	IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)	Mouse	HEK293 Cells
	Interleukin (IL)-1R3 is the co-receptor in three signaling pathways that involve six cytokines of the IL-1 family (IL-1α, IL-1β, IL-33, IL-36α, IL-36β and IL-36γ). In many diseases, multiple cytokines contribute to disea...
TMPK-00412	Gp130/IL6ST Protein, Human, Recombinant (His)	Human	HEK293 Cells
	gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic fa...
TMPY-01033	IL-32 Protein, Human, Recombinant (isoform alpha, His)	Human	HEK293 Cells
	IL-32 is a recently discovered cytokine that induces various proinflammatory cytokines (TNF-alpha, IL-1beta, IL-6) and chemokines in both human and mouse cells through the NF-kappaB and p38 MAPK inflammatory signal pathw...
TMPY-06479	Cathepsin H Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,...
TMPJ-00617	IL-33 Protein, Rhesus macaque, Recombinant (His)	Rhesus	E. coli
	Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the pr...
TMPK-00136	ULBP-2 Protein, Human, Recombinant (His & Avi)	Human	HEK293 Cells
	ULBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2, STAT5, E...
TMPH-03545	Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-02306	VTI1B Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusi...
TMPY-04081	Cathepsin H Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Proinflammatory cytokines decreased the expression of CTSH in human islets and primary rat beta-cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptosis. Cathepsin H Protein,...
TMPY-02724	XCL2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	XCL2 is a small cytokine belonging to the XC chemokine family. Chemokines are a group of cytokines. Members of this group of so-called C-Chemokines belong to the SCY family of cytokines and are designated XCL (L for liga...
TMPK-01520	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01521	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01484	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01436	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01478	HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01477	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01417	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPH-03539	Enterotoxin type B Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	P. pastoris (Yeast)
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPY-04260	P38 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TMPK-00920	IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	The interleukin (IL)-1 family of cytokines is currently comprised of 11 members that have pleiotropic functions in inflammation and cancer. IL-1α and IL-1β were the first members of the IL-1 family to be described, and b...
TMPK-01172	IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated	Mouse	E. coli
	Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological process...
TMPY-02795	Eotaxin-2 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in imm...
TMPK-01483	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01482	HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01519	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01515	HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)	Human	HEK293 Cells
	Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-00035	IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
	Interleukin-4, also known as IL4, is a secreted protein which belongs to the IL-4 / IL-13 family. Interleukin-4 / IL4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation.In t...
TMPK-00014	CXCL4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 a...
TMPH-03543	Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-01021	BTN3A1 Protein, Human, Recombinant (E. coli, His)	Human	E. coli
	Plays a role in T-cell activation and in the adaptive immune response. Regulates the proliferation of activated T-cells. Regulates the release of cytokines and IFNG by activated T-cells. Mediates the response of T-cells ...
TMPH-03542	Enterotoxin type C-2 Protein, S. aureus, Recombinant	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPK-00043	IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological process...
TMPK-00012	CXCL4 Protein, Human, Recombinant (His & Avi)	Human	E. coli
	Chemokines regulate leukocyte migration during physiological and pathological conditions. It is currently accepted that these chemotactic cytokines are also important in the development and progression of cancer. CXCL4 a...
TMPK-00052	IL-20 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPK-01198	IL-20 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Interleukin (IL)-20 is a member of the IL-10 family of cytokines, which has been reported to participate in autoimmune inflammatory diseases. However, the potential role of IL-20 in hepatocellular carcinoma (HCC) progres...
TMPH-01464	HNRNPM Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling ...
TMPH-03540	Enterotoxin type B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPK-00259	Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated	Human	HEK293 Cells
	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen...
TMPK-00710	Claudin-4 Protein-VLP, Human, Recombinant	Human	HEK293 Cells
	Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been asso...
TMPK-00893	PGF Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Placental growth factor (PGF) is another member of the VEGF family of cytokines with pro-angiogenic and pro-inflammatory effects. Retinal inhibition of PGF in combination with VEGF-A prevents vascular leakage and CNV pos...
TMPK-00258	Latent TGF beta 3 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differen...
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IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

IL-33 Protein, Mouse, Recombinant

TMPJ-01210

Species: Mouse

Expression System: E. coli

C-Reactive Protein /CRP Protein, Human, Recombinant (His)

TMPK-00114

Species: Human

Expression System: HEK293 Cells

M-CSF/CSF1 Protein, Human, Recombinant (His)

TMPJ-00327

Species: Human

Expression System: HEK293 Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

TMPJ-01467

Species: Human

Expression System: E. coli

TLR4 Protein, Human, Recombinant (His)

TMPY-02904

Species: Human

Expression System: Baculovirus Insect Cells

IL-15RA & IL-15 Protein, Human, Recombinant (hFc)

TMPJ-01461

Species: Human

Expression System: HEK293 Cells

IL-15RA & IL-15 Protein, Human, Recombinant - PBS Lyophilized (hFc)

TMPJ-01462

Species: Human

Expression System: HEK293 Cells

gp130/IL6ST Protein, Rhesus macaque, Recombinant (His)

TMPK-00646

Species: Rhesus

Expression System: HEK293 Cells

IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (aa 21-367, His)

TMPK-01029

Species: Mouse

Expression System: HEK293 Cells

gp130/IL6ST Protein, Human, Recombinant (His)

TMPK-00412

Species: Human

Expression System: HEK293 Cells

IL-32 Protein, Human, Recombinant (isoform alpha, His)

TMPY-01033

Species: Human

Expression System: HEK293 Cells

Cathepsin H Protein, Human, Recombinant (His)

TMPY-06479

Species: Human

Expression System: HEK293 Cells

IL-33 Protein, Rhesus macaque, Recombinant (His)

TMPJ-00617

Species: Rhesus

Expression System: E. coli

ULBP-2 Protein, Human, Recombinant (His & Avi)

TMPK-00136

Species: Human

Expression System: HEK293 Cells

Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03545

Species: Staphylococcus aureus

Expression System: E. coli

VTI1B Protein, Human, Recombinant (His & SUMO)

TMPH-02306

Species: Human

Expression System: E. coli

Cathepsin H Protein, Mouse, Recombinant (His)

TMPY-04081

Species: Mouse

Expression System: HEK293 Cells

XCL2 Protein, Human, Recombinant (His)

TMPY-02724

Species: Human

Expression System: Baculovirus Insect Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01520

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi)

TMPK-01521

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

TMPK-01484

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01436

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01478

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01477

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled

TMPK-01417

Species: Human

Expression System: HEK293 Cells

Enterotoxin type B Protein, S. aureus, Recombinant (His)

TMPH-03539

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

p38 Protein, Human, Recombinant (His)

TMPY-04260

Species: Human

Expression System: Baculovirus Insect Cells

IL-1 alpha/IL-1A Protein, Cynomolgus, Recombinant (His)

TMPK-00920

Species: Cynomolgus

Expression System: HEK293 Cells

IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated

TMPK-01172

Species: Mouse

Expression System: E. coli

Eotaxin-2 Protein, Human, Recombinant (His)

TMPY-02795

Species: Human

Expression System: Baculovirus Insect Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated

TMPK-01483

Species: Human

Expression System: HEK293 Cells

HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01482

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)

TMPK-01519

Species: Human

Expression System: HEK293 Cells

HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)

TMPK-01515

Species: Human

Expression System: HEK293 Cells

IL-4 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00035

Species: Human

Expression System: HEK293 Cells

CXCL4 Protein, Human, Recombinant (hFc)

TMPK-00014

Species: Human

Expression System: HEK293 Cells

Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO)

TMPH-03543

Species: Staphylococcus aureus

Expression System: E. coli

BTN3A1 Protein, Human, Recombinant (E. coli, His)

TMPH-01021

Species: Human

Expression System: E. coli

Enterotoxin type C-2 Protein, S. aureus, Recombinant

TMPH-03542

Species: Staphylococcus aureus

Expression System: E. coli

IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00043

Species: Human

Expression System: E. coli

CXCL4 Protein, Human, Recombinant (His & Avi)

TMPK-00012

Species: Human

Expression System: E. coli

IL-20 Protein, Human, Recombinant (His)

TMPK-00052

Species: Human

Expression System: HEK293 Cells

IL-20 Protein, Mouse, Recombinant (His)

TMPK-01198

Species: Mouse

Expression System: HEK293 Cells

HNRNPM Protein, Human, Recombinant (His & SUMO)

TMPH-01464

Species: Human

Expression System: E. coli

Enterotoxin type B Protein, S. aureus, Recombinant (GST)

TMPH-03540

Species: Staphylococcus aureus

Expression System: E. coli

Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated

TMPK-00259

Species: Human

Expression System: HEK293 Cells

Claudin-4 Protein-VLP, Human, Recombinant

TMPK-00710

Species: Human

Expression System: HEK293 Cells

PGF Protein, Human, Recombinant (hFc)

TMPK-00893

Species: Human

Expression System: HEK293 Cells

Latent TGF beta 3 Protein, Human, Recombinant (His)

TMPK-00258

Species: Human

Expression System: HEK293 Cells

--------- More ---------

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L6140	Saccharide and Glycoside Natural Product Library	362 compounds
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L2500	Human Endogenous Metabolite Library	499 compounds
	A collection of 499 selected human endogenous metabolites for high throughput and high content screening.
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L9420	Exosome Compound Library	76 compounds
	76 exosome-related compounds that can be used for high-throughput and high-content screening.