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Search Results for " induced "

ターゲット

Hedgehog/Smoothened

1893

阻害剤

737

天然化合物

1018

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T23027	MRT-10		Hedgehog/Smoothened
	MRT-10 is a Smoothened (Smo) receptor antagonist.		Hedgehog/Smoothened
T5491	GSK3179106		c-RET
	GSK3179106 is RET kinase inhibitor with an IC50 of 0.4 nM		c-RET
TP1889	MCL0020	MCL 0020	Melanocortin Receptor
	MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no e...		Melanocortin Receptor
TQ0105	CAY10650		Phospholipase
	CAY10650 is an effective inhibitor of cytosolic phospholipase A2α (cPLA2α, IC50: 12 nM).		Phospholipase
T23312	SB 204741		5-HT Receptor
	SB 204741 is a selective 5-HT2B antagonist with high affinity and pKi value of 7.1.		5-HT Receptor
T9266	Fatostatin		Lipid , Fatty Acid Synthase
	Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs.		Lipid , Fatty Acid Synthase
T9614	MERS-CoV-IN-1		SARS-CoV
	MERS-CoV-IN-1 exhibits excellent inhibitory activity against coronavirus.It is useful as a pharmaceutical composition for preventing coronavirus-induced diseases (MERS-CoV and SARS).		SARS-CoV
T7954	YM976		PDE
	YM976 is an orally active PDE4 inhibitor (IC50:2.2 nM)		PDE
T1997	JNJ-31020028	JNJ 31020028	Neuropeptide Y Receptor
	JNJ-31020028 is a selective brain penetrant antagonist of neuropeptide Y2 receptor with high affinity(pIC50=8.07, human; pIC50=8.22, rat); it exhibits >100-fold selectivity for Y2 versus human Y1/Y4/Y5 receptors.		Neuropeptide Y Receptor
T16481	PF-04995274		5-HT Receptor
	PF-04995274 is an effective, high-affinity, and partial serotonin 4 receptor (5-HT4R) agonist. PF-04995274 is brain penetrant and can be used for cognitive disorders associated with Alzheimer's disease. PF-04995274 has a...		5-HT Receptor
T21807	INCA-6	Triptycene-1,4-quinone	Others
	INCA-6 (Triptycene-1,4-quinone) is a cell-permeable NFAT inhibitor. INCA-6 inhibits of CN-NFAT signaling by targeting of NFAT(P) substrate to the calcineurin (CN) phosphatase site.		Others
T8235	L-732138		Neurokinin receptor
	L-732138 is a potent and competitive antagonist of neurokinin-1 (NK-1) receptor(IC50 : 2.3 nM)		Neurokinin receptor
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T1893	Parmodulin 2	ML 161	Protease-activated Receptor
	Parmodulin 2 (ML 161) is the inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50: 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). It also inhibits thromb...		Protease-activated Receptor
T2040	OAC1	BAS 00287861	OCT
	OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.		OCT
T0839	Ketoprofen	RP-19583	Apoptosis , COX , MRP
	Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenas...		Apoptosis , COX , MRP
T20759	XRP44X	XRP-44-X,XRP 44X,XRP-44X,XRP 44 X	Ras
	XRP44X (XRP 44X) is a potent inhibitor of Ras-Net (Elk-3) pathway.		Ras
T39308	Boc-Asp(OMe)-fluoromethyl ketone	Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK	Caspase
	Boc-Asp(OMe)-fluoromethyl ketone (Boc-Asp(OMe)-FMK) is a broad range caspase inhibitor. Boc-Asp(OME)-Fluoromethyl Ketone inhibits Fas-mediated phagocytosis and oxidative rupture inhibition, but does not affect the chemot...		Caspase
T9138	Indirubin-3′-oxime	Indirubin-3'-monoxime	GSK-3 , CDK , JNK
	Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.		GSK-3 , CDK , JNK
T2125	Trametinib	GSK1120212,JTP-74057	Apoptosis , MEK , Autophagy
	Trametinib (GSK1120212) is a MEK inhibitor that inhibits MEK1 and MEK2 (IC50=0.7/0.9 nM) with ATP non-competitive and oral activity. Trametinib activates autophagy and induces apoptosis.		Apoptosis , MEK , Autophagy
T6832	Fatostatin hydrobromide	Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin	NPC1L1 , Fatty Acid Synthase
	Fatostatin hydrobromide (Fatostatin A HBr) ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation of SREBP-1 and SREBP-2.		NPC1L1 , Fatty Acid Synthase
T0947	Dexamethasone acetate	Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471	Glucocorticoid Receptor , Mitophagy , IL Receptor , Annexin A , NOS , Antibacterial , Autophagy
	Dexamethasone acetate (NSC 39471) is the acetate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexa...
T1790	Fosaprepitant dimeglumine	L785298,MK-0517,Fosaprepitant dimeglumine salt	Neurokinin receptor
	Fosaprepitant dimeglumine (MK-0517) is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion...		Neurokinin receptor
T5857	Trametinib (DMSO solvate)	Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)	Apoptosis , MEK
	Trametinib (DMSO solvate) (GSK-1120212 (DMSO solvate)) is a Highly Potent and Selective MEK Inhibitor that specifically inhibits MEK1/2(IC50 :2 nM)		Apoptosis , MEK
T14848	C 87		Others , TNF
	C 87 is a small-molecule TNF-α inhibitor. C 87 directly binds to TNFα, potently inhibits TNF-α-induced cytotoxicity (IC50 = 8.73 μM), and effectively blocks TNF-α-triggered signaling activities.		Others , TNF
T10239	Acolbifene	EM-652,SCH 57068	Estrogen Receptor/ERR
	Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.		Estrogen Receptor/ERR
T21584	CP 465022		iGluR
	CP 465022 hydrochloride is a potent, and selective noncompetitive antagonist of AMPA receptor with anticonvulsant activity. CP 465022 hydrochloride inhibits Kainate-induced response with an IC50 of 25 nM in rat cortical ...		iGluR
T16850	SB-265610	GSK-CXCR2	CXCR
	SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis (IC50s: 3.7 nM and...		CXCR
T7604	Valrubicin	Valstar,AD-32	Antibiotic , PKC
	Valrubicin (AD-32) (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.		Antibiotic , PKC
T5133	Dabigatran Etexilate Mesylate	BIBR 1048MS,Dabigatran etexilate methanesulfonate	Thrombin
	Dabigatran Etexilate Mesylate (BIBR 1048MS) is the orally active prodrug of dabigatran. Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI, Ki: 4.5 nM).		Thrombin
T1282	Carteolol hydrochloride	Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan	Adrenergic Receptor
	Carteolol hydrochloride (Abbott-43326) is a synthetic quinolinone derivative, antihypertensive Carteolol Hydrochloride is a nonselective beta-adrenoceptor blocking agent for beta-1 and beta-2 receptors with no membrane-s...		Adrenergic Receptor
T33647L	Nesosteine Lithium	Nesosteine Lithium(84233-61-4 Free baes)
	Nesosteine Lithium is a novel mucoregulatory that inhibits Herxheimer microconvulsions in guinea pigs and inhibits ovalbumin-induced histamine release from sensitized trachea.Nesosteine Lithium protects against ovalbumin...
T79600	Zharp2-1		RIP kinase
	Zharp2-1, a RIPK2 inhibitor, inhibits the transcription of inflammatory cytokines induced by MDP-induced or Listeria monocytogenes infection and alleviates MDP-induced peritonitis symptoms in mice, which can be used for ...		RIP kinase
T28655	Sabeluzole	R 58735,R58735,R-58735	Microtubule Associated
	Sabeluzole (R-58735) has antiepileptic and cognitive enhancing effects, inhibits neurotoxin-induced tau expression and cell death.Sabeluzole is protective against chlordiazepoxide-induced habituation disorders and may be...		Microtubule Associated
T14551	Bevenopran	CB-5945,ADL-5945	Opioid Receptor
	Bevenopran (CB-5945) is a peripheral antagonist of μ-opioid receptor and can be used in studies about the treatment of opioid-induced bowel dysfunction.		Opioid Receptor
T0235	Modaline sulfate		MAO , Monoamine Oxidase
	Modaline was a 2-methyl-3-piperidinopyrazine derivative found to inhibit monoamine oxidase (MAO) and showed a curative effect for the anti-depressant. Similar to other MAO inhibitors, it enhanced convulsions induced by t...		MAO , Monoamine Oxidase
T3106	C-DIM12		Apoptosis , Others
	C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure ...		Apoptosis , Others
T14689	BMS493	BMS-493	Phospholipase , Retinoid Receptor
	BMS493 is an inverse agonist of the pan-retinoic acid receptor (RAR) that inhibits retinoic acid-induced differentiation, enhances the interaction of nuclear co-inhibitors with RARs, attenuates RA signaling, potentiates ...		Phospholipase , Retinoid Receptor
T25450	GGTI 2147	GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147	NF-κB , Rho
	GGTI 2147 decreased Rac1 activity, down-regulated p65 expression, and ameliorated OGD/R-induced neuronal apoptosis.		NF-κB , Rho
T61531	NFATc1-IN-1		RANKL/RANK
	NFATc1-IN-1 (also known as compound A04) is a highly effective inhibitor of osteoclast formation induced by RANKL, with an IC50 of 1.57 μM. It exerts its anti-osteoclastogenic effects by attenuating the RANKL-induced nuc...		RANKL/RANK
T7102	BCTC		TRP/TRPV Channel
	BCTC is a potent TRPV1 antagonist that inhibits capsaicin-induced and acid-induced activation of rat TRPV1 (IC50 of 35 and 6 nM, respectively)		TRP/TRPV Channel
T15681	L-161982		Prostaglandin Receptor
	L-161982 is a selective antagonist of EP4 receptor. L-161982 could inhibit PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 could alleviate collagen-induced arthritis in mice.		Prostaglandin Receptor
T72662	NMDAR/TRPM4-IN-2		ERK , TRP/TRPV Channel , NMDAR , iGluR
	NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprot...		ERK , TRP/TRPV Channel , NMDAR , iGluR
T64394	GW 833972A		Cannabinoid Receptor
	GW 833972A is a selective CB2 receptor agonist.GW 833972A has an inhibitory effect on induced neural depolarization and on citric acid-induced cough in an animal model.		Cannabinoid Receptor
T22984	MJ 15		Cannabinoid Receptor
	MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.		Cannabinoid Receptor
T74186	PROTAC-O4I2		Apoptosis , PROTACs
	PROTAC-O4I2, a PROTAC ligand targeting splicing factor 3B1 (SF3B1), induced FLAG-SF3B1 degradation in K562 cells with an IC50 value of 0.244 μM. PROTAC-O4I2 induced apoptosis in K562 WT cells.		Apoptosis , PROTACs
T34435	RU 47213	RU-47213,Itameline,RU47213	Others
	RU 47213 can be used to inhibit scopolamine-induced working memory impairment in rats.		Others
T22346	Indomethacin sodium hydrate	Indometacin sodium hydrate	COX
	Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries,...		COX
T28918	Talviraline	Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979	HIV Protease , DNA/RNA Synthesis
	Talviraline (Bay 10-8979) is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of human cell lines, as well as in fresh human perip...		HIV Protease , DNA/RNA Synthesis
T3536	AZD1283		P2Y Receptor
	AZD1283 is an effective P2Y12 receptor antagonist (EC50: 3.0 ug/kg/min, binding IC50: 11 nM). AZD1283 dose-dependently induced increases in blood flow and inhibition of ADP-induced platelet aggregation with antithromboti...		P2Y Receptor

Compounds

MRT-10

T23027

Synonym:

Target: Hedgehog/Smoothened

Target: Melanocortin Receptor

CAY10650

TQ0105

Synonym:

Target: Phospholipase

SB 204741

T23312

Synonym:

Target: 5-HT Receptor

Fatostatin

T9266

Synonym:

Target: Lipid, Fatty Acid Synthase

Synonym: JNJ 31020028

Target: Neuropeptide Y Receptor

PF-04995274

T16481

Synonym:

Target: 5-HT Receptor

INCA-6

T21807

Synonym: Triptycene-1,4-quinone

Target: Neurokinin receptor

MAZ51

T8496

Synonym:

Target: Apoptosis, VEGFR

Parmodulin 2

T1893

Synonym: ML 161

Target: Protease-activated Receptor

OAC1

T2040

Synonym: BAS 00287861

Target: Apoptosis, COX, MRP

XRP44X

T20759

Synonym: XRP-44-X,XRP 44X,XRP-44X,XRP 44 X

Target: Ras

Boc-Asp(OMe)-fluoromethyl ketone

T39308

Synonym: Boc-Asp(OMe)-fluoromethyl ketone,Boc-Asp(OMe)-FMK

Target: Caspase

Indirubin-3′-oxime

T9138

Synonym: Indirubin-3'-monoxime

Target: GSK-3, CDK, JNK

Trametinib

T2125

Synonym: GSK1120212,JTP-74057

Target: Apoptosis, MEK, Autophagy

Fatostatin hydrobromide

T6832

Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

Target: NPC1L1, Fatty Acid Synthase

Dexamethasone acetate

T0947

Synonym: Dexamethasone 21-acetate,Dexamethason acetate,NSC 39471

Target: Glucocorticoid Receptor, Mitophagy, IL Receptor, Annexin A, NOS, Antibacterial, Autophagy

Fosaprepitant dimeglumine

T1790

Synonym: L785298,MK-0517,Fosaprepitant dimeglumine salt

Target: Neurokinin receptor

Trametinib (DMSO solvate)

T5857

Synonym: Trametinib DMSO solvate,GSK-1120212 (DMSO solvate),Trametinib dimethyl sulfoxide,JTP-74057 (DMSO solvate)

Target: Apoptosis, MEK

Synonym: EM-652,SCH 57068

Target: Estrogen Receptor/ERR

Synonym: Valstar,AD-32

Target: Antibiotic, PKC

Dabigatran Etexilate Mesylate

T5133

Synonym: BIBR 1048MS,Dabigatran etexilate methanesulfonate

Target: Thrombin

Carteolol hydrochloride

T1282

Synonym: Arteoptic,Abbott-43326,OPC-1085 hydrochloride,Carteolol HCl,Mikelan

Target: Adrenergic Receptor

Nesosteine Lithium

T33647L

Synonym: Nesosteine Lithium(84233-61-4 Free baes)

Synonym: R 58735,R58735,R-58735

Target: Microtubule Associated

Bevenopran

T14551

Synonym: CB-5945,ADL-5945

Target: Opioid Receptor

Modaline sulfate

T0235

Synonym:

Target: MAO, Monoamine Oxidase

C-DIM12

T3106

Synonym:

Target: Apoptosis, Others

BMS493

T14689

Synonym: BMS-493

Target: Phospholipase, Retinoid Receptor

GGTI 2147

T25450

Synonym: GGTI2147,Geranylgeranyl transferase inhibitor-2147,GGTI-2147

Target: TRP/TRPV Channel

L-161982

T15681

Synonym:

Target: Prostaglandin Receptor

NMDAR/TRPM4-IN-2

T72662

Synonym:

Target: ERK, TRP/TRPV Channel, NMDAR, iGluR

GW 833972A

T64394

Synonym:

Target: Cannabinoid Receptor

MJ 15

T22984

Synonym:

Target: Cannabinoid Receptor

PROTAC-O4I2

T74186

Synonym:

Target: Apoptosis, PROTACs

RU 47213

T34435

Synonym: RU-47213,Itameline,RU47213

Target: Others

Indomethacin sodium hydrate

T22346

Synonym: Indometacin sodium hydrate

Target: COX

Talviraline

T28918

Synonym: Bay 10-8979,HBY 097,Bay10-8979,Bay-108979,Bay108979,Bay 108979,Bay-10-8979

Target: HIV Protease, DNA/RNA Synthesis

カタログ番号	製品名	別名	ターゲット
T6S1027	Tussilagone		Others
	1. Tussilagone inhibits dendritic cell function through the induction of heme oxygenase-1. 2. Tussilagone has anti-cancer activity, might be a potential chemotherapeutic agent for the prevention and treatment of human co...		Others
T5826	Eupalinolide A		HSP
	Eupalinolide B is a natural product ,and demonstrates potent cytotoxicity against A-549, BGC-823, SMMC-7721, and HL-60 tumour cell lines.		HSP
T3804	Neomangiferin	Mangiferin 7-glucoside	Phosphatase
	Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...		Phosphatase
T4S0537	Neoline	Bullatine B	Others
	Neoline (Bullatine B) shows analgesic/anti-inflammatory properties.		Others
T2988	(-)-Epigallocatechin Gallate	Epigallocatechol Gallate,EGCG	Ferroptosis , Reactive Oxygen Species , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite , Autophagy
	(-)-Epigallocatechin Gallate (EGCG) is an antioxidant polyphenol flavonoid that inhibits telomerase and DNA methyltransferase. (-)-Epigallocatechin Gallate (EGCG) blocks the activation of EGF receptors and HER-2 receptor...
TN6714	Geranylgeraniol	FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095	Apoptosis
	Geranylgeraniol (FT0626663) is an isoprenoid found in fruits, vegetables, and grains, including rice. Geranylgeraniol (FT0626663) inhibits growth and induces apoptosis of various tumor cells. Geranylgeraniol (FT0626663) ...		Apoptosis
TN1624	Ethyl cinnamate		Calcium Channel , ROS , NO Synthase
	Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl...		Calcium Channel , ROS , NO Synthase
T3S0488	Syringaresinol diglucoside	Syringaresinol-di-O-glucoside	Others
	Syringaresinol diglucoside (Syringaresinol-di-O-glucoside) protects the animals from the stress-induced decreases in sex behaviours and in rectal temperature, the stress-induced failure of retrieval of memory, and the st...		Others
TQ0226	Jionoside B1		Others
	Jionoside B1 has immunosuppressive activity and shows the hepato-protective activity in the H2O2 induced liver injury experiments.		Others
TN3460	Asebogenin		Antifungal
	Asebogenin is a compound fractionated from Salvia miltiorrhiza with antifungal activity, inhibition of GPVI-induced platelet reactions, and inhibition of NET formation induced by pro-inflammatory stimuli.		Antifungal
T6S0654	Isocorynoxeine	7-Isocorynoxeine	5-HT Receptor
	1. Isocorynoxeine (7-Isocorynoxeine) shows the effects of lowering blood pressure, vasodilatation, and protection against ischemia-induced neuronal damage. 2. Isocorynoxeine exhibits a significant neuroprotective effect ...		5-HT Receptor
TN1594	DL-Syringaresinol	(±)-Syringaresinol	Antioxidant , Antifungal
	DL-Syringaresinol ( (±)-Syringaresinol) is a lignan from ginseng berries with anti-inflammatory, antioxidant, analgesic and weak anti-mycobacterial activities.DL-Syringaresinol can delay oxidative stress-induced skin agi...		Antioxidant , Antifungal
T3860	Isoliquiritin apioside		MMP , p38 MAPK , NF-κB
	Isoliquiritin apioside, isolated from Glycyrrhizae radix rhizome, significantly decreases PMA-induced increases in MMP9 activities and suppresses PMA-induced activation of MAPK and NF-κB. Isoliquiritin apioside auppresse...		MMP , p38 MAPK , NF-κB
T5760	(-)-Salutaridine	SINOACUTINE	Others
	(-)-Salutaridine is a natural product isolated from Stephania epigaea Lo.Sinoacutine has protective effects against hydrogen peroxide-induced cell injury.		Others
T2804	Panaxatriol	Panaxtriol	Others
	Panaxatriol (Panaxtriol) can relieve myelosuppression induced by radiation injury.		Others
T0632	3,4,5-Trimethoxybenzoic acid	Gallic acid trimethyl ether,Eudesmic acid,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid	Antioxidant
	3,4,5-Trimethoxybenzoic acid (Gallic acid trimethyl ether) are potent antioxidants and inhibitor of cytokine production. It can ameliorate chronic stress-induced various behavioral and biochemical alterations in mice. It...		Antioxidant
TN1256	3-O-Acetyl-16α-hydroxytrametenolic acid	3-O-Acetyl-16 alpha-hydroxytrametenolic acid	Immunology/Inflammation related
	3-O-Acetyl-16α-hydroxytrametenolic acid has inhibitory activities against AAPH-induced hemolysis of red blood cells, it shows a strong inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate-induced inflammation...		Immunology/Inflammation related
TN2315	Xanthopurpurin		Platelet aggregation , Antifection
	Xanthopurpurin shows antiviral activity. Xanthopurpurin can effectively inhibit rotavirus multiplication by promoting virus-induced apoptosis in MA-104 cells. Xanthopurpurin shows mainly strong inhibition of collagen-ind...		Platelet aggregation , Antifection
TN1031	Poricoic acid B		Others
	Poricoic acid B shows inhibitory activity against TPA-induced ear inflammatory oedema, it also shows potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-te...		Others
TN5171	Tricetin		Apoptosis , Others , Nrf2
	Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ...		Apoptosis , Others , Nrf2
T8024	3-Indoleacetonitrile		Others , Endogenous Metabolite
	3-Indoleacetonitrile is a light-induced auxin-inhibitory substance that is isolated from light-grown cabbage shoots.		Others , Endogenous Metabolite
T8704	4-hydroxyphenyl acetate		Nrf2
	4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer		Nrf2
TN2540	1-Hydroxybaccatin I		Others
	1-Hydroxybaccatin I possesses significant antinociceptive activity against p- benzoquinone-induced abdominal contractions.		Others
T4035	Khasianine		Others
	Khasianine has strong activity against liver damage induced by CCl4.		Others
TN1038	Galgravin		Apoptosis
	Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protec...		Apoptosis
T6S1423	Praeruptorin B		Others
	1. Praeruptorin B can inhibit tumor promoter induced phemonenon in vitro.		Others
T5702	Tenuifoliside B		Dehydrogenase
	Tenuifoliside B is a natural product from the roots of Polygala tenuifolia.And is a target lactate dehydrogenase inhibitor. Tenuifoliside B has cognitive improving and cerebral protective effects. it can inhibit potassi...		Dehydrogenase
TN2330	Phenethyl ferulate	Caffeic Acid 3-Methyl Phenethyl Ester	Lipoxygenase , COX
	Phenethyl ferulate (Caffeic Acid 3-Methyl Phenethyl Ester) has chemopreventive properties against chemically induced colon carcinogenesis. It enhances apoptosis in azoxymethane induced colon tumors. It shows inhibitory a...		Lipoxygenase , COX
T3717	Hinokitiol	4-Isopropyltropolone,β-thujaplicin	DNA Methyltransferase , Virus Protease , Estrogen/progestogen Receptor , Nrf2
	Hinokitiol (4-Isopropyltropolone) can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent...
TN1441	Beta-Tocopherol		ERK , MAPK
	Beta-Tocopherol shows effect on human erythroleukemia cell (HEL) adhesion induced by phorbol 12-myristate 13-acetate (PMA).		ERK , MAPK
TN2436	4-methyl-6-phenyl-2H-pyranone	4-methyl-6-phenyl-2H-pyranone	Mitochondrial Metabolism
	4-methyl-6-phenyl-2H-pyranone is derived from Scutellaria baicalensis Georgi and improves mitochondrial functionality to protect astrocytes against hydrogen peroxide-induced toxicity.		Mitochondrial Metabolism
T6S2099	Geraniin		Antioxidant , TNF
	1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Geraniin exerts inhibitory effects on osteoclast differentiation ...		Antioxidant , TNF
T2916	Patchouli alcohol	Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol	Antibacterial , Antifungal
	Patchouli alcohol (Patchoulol) is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions. Patchouli alcohol also suppresses inflammation induced by lipopolysaccharide in v...		Antibacterial , Antifungal
TN6975	Cirsiumaldehyde	5,5’-oxydimethylenebis(2-furfural)	Platelet aggregation
	Cirsiumaldehyde is a compound isolated from the mature fruits of Lobelia chinensis, Cornus officinalis, and the fruits of Hippophae rhamnoides.Cirsiumaldehyde in the presence of collagen inhibited U46619-induced (1~5 uM)...		Platelet aggregation
TMA1570	Sappanone A		NF-κB , Nrf2
	Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.		NF-κB , Nrf2
T3753	Sinapinic Acid	Sinapic acid,Synapoic acid	Apoptosis , RAAS , Reactive Oxygen Species , HDAC
	Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...		Apoptosis , RAAS , Reactive Oxygen Species , HDAC
T5764	Alliin	(S)-3-(Allylsulphinyl)-L-alanine	NF-κB , PPAR
	Alliin ((S)-3-(Allylsulphinyl)-L-alanine) is a garlic organosulfur compound that possesses various pharmacological properties.alliin protected against LPS-induced ALI by activating PPARγ, which subsequently inhibited LPS...		NF-κB , PPAR
T5S1097	Neferine	(R)-1,2-Dimethoxyaporphine,(-)-Neferine	Apoptosis , NF-κB , Autophagy
	1. Neferine ((-)-Neferine) has anti-tumor activities , Metabolic activation mediated by CYP3A4 and GSH depletion enhanced Neferine-induced cytotoxicity. 2. Neferine can be helpful to increase the efficacy of DOX and to a...		Apoptosis , NF-κB , Autophagy
TN3469	Aucuparin	2,6-dimethoxy-4-phenylphenol	NADPH-oxidase
	Aucuparin (2,6-dimethoxy-4-phenylphenol) is a plant antibiotic with anti-inflammatory activity. Aucuparin inhibited pulmonary fibrosis in mouse models induced by bleomycin (BLM). ABTS and FRAP showed clear scavenging act...		NADPH-oxidase
TN1643	Ferulamide	4-Hydroxy-3-methoxycinnamide	PAFR , AChR
	Ferulamide (4-Hydroxy-3-methoxycinnamide), a Ferulic acid derivative, shows potent inhibitory activity against arachidonic acid-induced platelet aggregation.		PAFR , AChR
T24711	Ricinine	1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile,Ricinin,Ritsinin	Others
	Ricinine (1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile) is a major alkaloid in Ricinus communis plant with hepatoprotection in CCl4 -induced liver damage.		Others
T5S2129	Sciadopitysin		TNF , NF-κB
	Sciadopitysin may prevent the development of diabetic osteopathy, it exerts its therapeutic effects via upregulation of mitochondrial biogenesis.Sciadopitysin shows protective effects on antimycin A-induced toxicity in o...		TNF , NF-κB
T3795	Corilagin		Apoptosis , TLR , Reverse Transcriptase , Antibacterial , Autophagy
	Corilagin has anti-inflammatory activity. Corilagin has a significant antitumour potential and lower toxicity in normal cells in vitro.Corilagin can enhance the cytotoxicity of both cisplatin and doxorubicin on the Hep3B...
T4S1725	Galanthamine	Galantamine	Apoptosis , AChE
	Galanthamine (Galantamine) is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.		Apoptosis , AChE
TN1353	N-Benzyllinoleamide	(9Z,12Z)-N-Benzyloctadeca-9,12-dienamide	Others
	N-Benzyllinoleamide ((9Z,12Z)-N-Benzyloctadeca-9,12-dienamide) is a natural product isolated from Lepidium meyenii Walp, has pharmaceutical property against exercise-induced fatigue.		Others
TN7217	4,6-Benzilidine-D-Glucose
	4,6-Benzilidine-D-Glucose is a clinical antitumor compound showing antitumor activity in rats with chemically induced hepatocellular carcinoma.
T6S2246	Alisol B 23-acetate	Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B	Others
	1. Alisol B 23-acetate (Alisol B Acetate) produces protective effect against ANIT-induced hepatotoxity and cholestasis, due to FXR-mediated regulation of transporters and enzymes. 2. Alisol B 23-acetate produces promotiv...		Others
T4S1050	Pristimerin	Celastrol methyl ester	NF-κB , Antibacterial
	1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...		NF-κB , Antibacterial
T1156	Palonosetron hydrochloride	RS 25259 197,Palonosetron HCl,RS 25259	5-HT Receptor
	Palonosetron hydrochloride (RS 25259) is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.		5-HT Receptor
T3S1628	Vitexin-4''-O-glucoside	Vitexin -4''-O-glucoside	Others
	Vitexin-4''-O-glucoside (Vitexin -4''-O-glucoside) could effectively protect ECV-304 cells against cytotoxicity induced by TBHP through resuming mitochondrial function.		Others
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天然物製品

Synonym: Mangiferin 7-glucoside

(-)-Epigallocatechin Gallate

T2988

Synonym: Epigallocatechol Gallate,EGCG

Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy

Geranylgeraniol

TN6714

Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,CJ-24095

Target: Calcium Channel, ROS, NO Synthase

Syringaresinol diglucoside

T3S0488

Synonym: Syringaresinol-di-O-glucoside

Synonym: 7-Isocorynoxeine

Target: 5-HT Receptor

DL-Syringaresinol

TN1594

Synonym: (±)-Syringaresinol

Target: Antioxidant, Antifungal

Isoliquiritin apioside

T3860

Synonym:

Target: MMP, p38 MAPK, NF-κB

3,4,5-Trimethoxybenzoic acid

T0632

Synonym: Gallic acid trimethyl ether,Eudesmic acid,Trimethylgallic Acid,Benzoic acid,Tri-O-methylgallic acid

Target: Antioxidant

3-O-Acetyl-16α-hydroxytrametenolic acid

TN1256

Synonym: 3-O-Acetyl-16 alpha-hydroxytrametenolic acid

Target: Immunology/Inflammation related

Xanthopurpurin

TN2315

Synonym:

Target: Platelet aggregation, Antifection

Target: Apoptosis, Others, Nrf2

3-Indoleacetonitrile

T8024

Synonym:

Target: Others, Endogenous Metabolite

4-hydroxyphenyl acetate

Target: Dehydrogenase

Phenethyl ferulate

TN2330

Synonym: Caffeic Acid 3-Methyl Phenethyl Ester

Target: Lipoxygenase, COX

Hinokitiol

T3717

Synonym: 4-Isopropyltropolone,β-thujaplicin

Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2

4-methyl-6-phenyl-2H-pyranone

TN2436

Synonym: 4-methyl-6-phenyl-2H-pyranone

Target: Mitochondrial Metabolism

Geraniin

T6S2099

Synonym:

Target: Antioxidant, TNF

Patchouli alcohol

T2916

Synonym: Patchouli camphor,Patchoulol,(-)-Patchouli Alcohol

Target: Antibacterial, Antifungal

Cirsiumaldehyde

TN6975

Synonym: 5,5’-oxydimethylenebis(2-furfural)

Target: Platelet aggregation

Synonym: Sinapic acid,Synapoic acid

Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC

Alliin

T5764

Synonym: (S)-3-(Allylsulphinyl)-L-alanine

Target: NF-κB, PPAR

Neferine

T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine

Target: Apoptosis, NF-κB, Autophagy

Aucuparin

TN3469

Synonym: 2,6-dimethoxy-4-phenylphenol

Target: NADPH-oxidase

Ferulamide

TN1643

Synonym: 4-Hydroxy-3-methoxycinnamide

Target: PAFR, AChR

Ricinine

T24711

Synonym: 1,2-Dihydro-4-methoxy-1-methyl-2-oxonicotinonitrile,Ricinin,Ritsinin

Target: Apoptosis, TLR, Reverse Transcriptase, Antibacterial, Autophagy

Galanthamine

T4S1725

Synonym: Galantamine

Target: Apoptosis, AChE

N-Benzyllinoleamide

TN1353

Synonym: (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide

Target: Others

4,6-Benzilidine-D-Glucose

Synonym: Alisol B Acetate,Alisol B monoacetate,23-O-Acetylalisol B,23-Acetylalismol B

Target: Others

Pristimerin

T4S1050

Synonym: Celastrol methyl ester

Target: NF-κB, Antibacterial

Palonosetron hydrochloride

T1156

Synonym: RS 25259 197,Palonosetron HCl,RS 25259

Target: 5-HT Receptor

Vitexin-4''-O-glucoside

T3S1628

Synonym: Vitexin -4''-O-glucoside

Target: Others

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-01008	VEGFD Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-01009	TGFBI Protein, Human, Recombinant (His)	Human	HEK293
	TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several ...
TMPY-00005	FGF-8a Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-06986	FGF-8b Protein, Human, Recombinant	Human	E. coli
	In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment...
TMPY-02603	STAT6 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6...
TMPJ-00884	CXCL9 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Chemokine (C-X-C motif) ligand 9 (CXCL9, MIG), is a small cytokine belonging to the CXC chemokine family. CXCL9 functions as one of the three ligands of chemokine receptor CXCR3 which is a G protein-coupled receptor foun...
TMPJ-01084	CXCL9 Protein, Human, Recombinant (His)	Human	Human Cells
	Chemokine (C-X-C Motif) Ligand 9 (CXCL9) belongs to the intercrine alpha (chemokine CXC) family. It is secreted by interferon stimulated monocytes, macrophages and endothelial cells, which elicits chemotactic functions b...
TMPY-00367	Chemerin/RARRES2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret...
TMPJ-00981	PTX3 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory...
TMPY-02841	Fragilis/IFITM3 Protein, Human, Recombinant (mFc)	Human	HEK293
	Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interf...
TMPY-03200	VEGFD Protein, Rat, Recombinant (hFc)	Rat	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse tumor necrosis factor ligand superfamily member 11(Tnfsf11) is a member of the tumor necrosis factor (TNF) cytokine family. Tnfsf11 is widely expressed in cells including T cells and T cell rich organs, such as thy...
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPJ-00546	EFNA1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Ephrin-A1 is a member of the A-type ephrin family of cell surface proteins that function as ligands for the A-type Eph receptor tyrosine kinase family. Ephrin-A1 can be induced by TNF and IL1B. Its expression levels can ...
TMPY-04143	Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Retinoic acid receptor responder protein 2 (RARRES2) is a small secreted protein involved in multiple cancers, including adrenocortical carcinoma (ACC). Serum RARRES2 may be used as a novel prognostic marker for ACC. Ret...
TMPH-00084	Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli with N-terminal 10xHis tag and C-terminal Myc tag. The predicted molecular weight is 28.4 kDa. Accession number: P42758
TMPJ-00495	ISG15 Protein, Human, Recombinant (His)	Human	E. coli
	Ubiquitin-Like Protein ISG15 (ISG15) is a ubiquitin-like protein that becomes conjugated to many cellular proteins upon activation by interferon-alpha and -beta. Several functions have been ascribed to the encoded protei...
TMPJ-00433	VSIR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling...
TMPH-02908	AICDA Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (...
TMPY-03150	VEGFD Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPH-00930	Anamorsin Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Anamorsin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPK-00660	AMIGO2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BE...
TMPK-01072	AMIGO2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Bromodomain and extraterminal domain inhibitors (BETi) represent promising therapeutic agents for metastatic melanoma, yet their mechanism of action remains unclear. Here we interrogated the transcriptional effects of BE...
TMPH-02641	ECEL1 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides.
TMPJ-00320	AMIGO2 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LR...
TMPY-02589	VEGFD Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPH-02510	ANGPTL8 Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storag...
TMPH-02509	ANGPTL8 Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storag...
TMPJ-00338	LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	The type I transmembrane protein 15-leucine-rich repeat containing membrane protein (LRRC15) is a member of the LRR superfamily. The LRR family is a structural module for protein-protein and protein-matrix interactions u...
TMPJ-00110	GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)	Mouse	Human Cells
	Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The p...
TMPJ-00082	NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Lipocalin-2, also known as Neutrophil Gelatinase-Associated Lipocalin (NGAL), is a secretory protein of the lipocalin superfamily. Lipocalin-2 contains a signal peptide that enables it to be secreted and form complexes w...
TMPJ-00008	CXCL10 Protein, Human, Recombinant (hFc & His)	Human	Human Cells
	Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types, such as monocytes, endothelial cells and fibroblasts, in response to IFN-γ. CXCL10 functions via chemokine receptor CX...
TMPJ-00022	LGALS7 Protein, Human, Recombinant	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosamine containing glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also poss...
TMPH-01556	EIF2AK2 Protein, Human, Recombinant (His)	Human	Yeast
	IFN-induced dsRNA-dependent serine/threonine-protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (EIF2S1/eIF-2-alpha) and plays a key role in the innate immune response to v...
TMPJ-01292	Chemerin/RARRES2 Protein, Human, Recombinant (His)	Human	Human Cells
	Retinoic acid receptor responder protein 2(RARRES2) is a secreted protein that in humans is encoded by the RARRES2 gene. It is highly expressed in skin, also found in pancreas, liver, spleen, prostate, ovary, small intes...
TMPJ-00883	EGR1 Protein, Human, Recombinant (His)	Human	E. coli
	EGR-1 belongs to the EGR family of C2H2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. EGR-1 recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site).The produc...
TMPJ-00432	GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	Human Cells
	TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell res...
TMPJ-01415	ANGPTL4 Protein, Mouse, Recombinant (hFc)	Mouse	Human Cells
	Angiopoietin-related protein 4（ANGPTL4）is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migratio...
TMPJ-01372	Cornulin Protein, Human, Recombinant (His)	Human	E. coli
	Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-ter...
TMPJ-01382	HSPB8 Protein, Human, Recombinant (His)	Human	E. coli
	Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in t...
TMPK-00785	ANXA2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	ANXA2, highly expressed in invasive breast cancer cells, is closely related with poor prognosis, and acts as a molecular switch to EGFR activation. ANXA2 expression is inversely correlated with cell sensitivity to gefiti...
TMPY-06842	BMP-4 Protein, Human, Recombinant (E399D)	Human	E. coli
	BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-05493	LIFR Protein, Human, Recombinant (hFc)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-00991	LIFR Protein, Human, Recombinant (His)	Human	HEK293
	LIFR (leukemia inhibitory factor receptor) belongs to the family of cytokine receptors. LIFR forms a high-affinity receptor complex with gp130, which mediates the activity of LIF (leukemia inhibitory factor) and thus aff...
TMPY-01066	MICB Protein, Human, Recombinant (His)	Human	HEK293
	MHC class I polypeptide-related sequence B, also known as MICB, is a heavily glycosylated protein serving as a ligand for the type II receptor NKG2D. MICB shares 85% amino acid identity with MICA, a closely related prote...
TMPY-01020	Periostin/OSF-2 Protein, Human, Recombinant (His)	Human	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPK-01246	GDF-15 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPY-01613	Periostin/OSF-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, ...
TMPY-03577	Pleiotrophin/PTN Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
TMPY-03235	BST2 Protein, Human, Recombinant (His)	Human	HEK293
	BST2 was frequently overexpressed in GC tissues compared with the adjacent non-tumorous tissues, and high BST2 expression was correlated with tumor stage and lymphatic metastasis. Furthermore, in vitro experiments demons...
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VEGFD Protein, Human, Recombinant (His)

TMPY-01008

Species: Human

Expression System: HEK293

TGFBI Protein, Human, Recombinant (His)

TMPY-01009

Species: Human

Expression System: HEK293

FGF-8a Protein, Human, Recombinant

TMPY-00005

Species: Human

Expression System: E. coli

FGF-8b Protein, Human, Recombinant

TMPY-06986

Species: Human

Expression System: E. coli

STAT6 Protein, Human, Recombinant (His)

TMPY-02603

Species: Human

Expression System: Baculovirus-Insect Cells

CXCL9 Protein, Mouse, Recombinant (His)

TMPJ-00884

Species: Mouse

Expression System: Human Cells

CXCL9 Protein, Human, Recombinant (His)

TMPJ-01084

Species: Human

Expression System: Human Cells

Chemerin/RARRES2 Protein, Mouse, Recombinant (His)

TMPY-00367

Species: Mouse

Expression System: HEK293

PTX3 Protein, Mouse, Recombinant (His)

TMPJ-00981

Species: Mouse

Expression System: Human Cells

Fragilis/IFITM3 Protein, Human, Recombinant (mFc)

TMPY-02841

Species: Human

Expression System: HEK293

VEGFD Protein, Rat, Recombinant (hFc)

TMPY-03200

Species: Rat

Expression System: HEK293

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

TMPJ-00607

Species: Mouse

Expression System: Human Cells

TNFAIP8 Protein, Human, Recombinant (His)

TMPY-03416

Species: Human

Expression System: E. coli

EFNA1 Protein, Human, Recombinant (hFc)

TMPJ-00546

Species: Human

Expression System: Human Cells

Chemerin/RARRES2 Protein, Mouse, Recombinant (hFc)

TMPY-04143

Species: Mouse

Expression System: HEK293

Dehydrin Xero 2 Protein, Arabidopsis thaliana, Recombinant (His & Myc)

TMPH-00084

Species: Arabidopsis thaliana

Expression System: E. coli

ISG15 Protein, Human, Recombinant (His)

TMPJ-00495

Species: Human

Expression System: E. coli

VSIR Protein, Cynomolgus, Recombinant (His)

TMPJ-00433

Species: Cynomolgus

Expression System: Human Cells

AICDA Protein, Mouse, Recombinant (His & Myc)

TMPH-02908

Species: Mouse

Expression System: E. coli

VEGFD Protein, Mouse, Recombinant (His)

TMPY-03150

Species: Mouse

Expression System: HEK293

Anamorsin Protein, Human, Recombinant (His & SUMO)

TMPH-00930

Species: Human

Expression System: E. coli

AMIGO2 Protein, Cynomolgus, Recombinant (His)

TMPK-00660

Species: Cynomolgus

Expression System: HEK293

AMIGO2 Protein, Mouse, Recombinant (His)

TMPK-01072

Species: Mouse

Expression System: HEK293

ECEL1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02641

Species: Mouse

Expression System: E. coli

AMIGO2 Protein, Human, Recombinant (hFc)

TMPJ-00320

Species: Human

Expression System: Human Cells

VEGFD Protein, Mouse, Recombinant (hFc)

TMPY-02589

Species: Mouse

Expression System: HEK293

ANGPTL8 Protein, Mouse, Recombinant (His)

TMPH-02510

Species: Mouse

Expression System: Yeast

ANGPTL8 Protein, Mouse, Recombinant (E. coli, His)

TMPH-02509

Species: Mouse

Expression System: E. coli

LRRC15 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00338

Species: Human

Expression System: Human Cells

GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)

TMPJ-00110

Species: Mouse

Expression System: Human Cells

NGAL/Lipocalin-2 Protein, Mouse, Recombinant (hFc)

TMPJ-00082

Species: Mouse

Expression System: Human Cells

CXCL10 Protein, Human, Recombinant (hFc & His)

TMPJ-00008

Species: Human

Expression System: Human Cells

LGALS7 Protein, Human, Recombinant

TMPJ-00022

Species: Human

Expression System: E. coli

EIF2AK2 Protein, Human, Recombinant (His)

TMPH-01556

Species: Human

Expression System: Yeast

Chemerin/RARRES2 Protein, Human, Recombinant (His)

TMPJ-01292

Species: Human

Expression System: Human Cells

EGR1 Protein, Human, Recombinant (His)

TMPJ-00883

Species: Human

Expression System: E. coli

GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)

TMPJ-00432

Species: Cynomolgus

Expression System: Human Cells

ANGPTL4 Protein, Mouse, Recombinant (hFc)

TMPJ-01415

Species: Mouse

Expression System: Human Cells

Cornulin Protein, Human, Recombinant (His)

TMPJ-01372

Species: Human

Expression System: E. coli

HSPB8 Protein, Human, Recombinant (His)

TMPJ-01382

Species: Human

Expression System: E. coli

ANXA2 Protein, Mouse, Recombinant (His)

TMPK-00785

Species: Mouse

Expression System: E. coli

BMP-4 Protein, Human, Recombinant (E399D)

TMPY-06842

Species: Human

Expression System: E. coli

LIFR Protein, Human, Recombinant (hFc)

TMPY-05493

Species: Human

Expression System: HEK293

LIFR Protein, Human, Recombinant (His)

TMPY-00991

Species: Human

Expression System: HEK293

MICB Protein, Human, Recombinant (His)

TMPY-01066

Species: Human

Expression System: HEK293

Periostin/OSF-2 Protein, Human, Recombinant (His)

TMPY-01020

Species: Human

Expression System: HEK293

GDF-15 Protein, Mouse, Recombinant (His)

TMPK-01246

Species: Mouse

Expression System: E. coli

Periostin/OSF-2 Protein, Mouse, Recombinant (His)

TMPY-01613

Species: Mouse

Expression System: HEK293

Pleiotrophin/PTN Protein, Mouse, Recombinant

TMPY-03577

Species: Mouse

Expression System: Baculovirus-Insect Cells

BST2 Protein, Human, Recombinant (His)

TMPY-03235

Species: Human

Expression System: HEK293

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