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Search Results for " diabetes "

ターゲット

Phosphorylase

541

阻害剤

天然化合物

165

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T6455	CP-91149		Phosphorylase
	CP-91149 is a selective glycogen phosphorylase (GP) inhibitor with IC50 of 0.13 μM in the presence of glucose, 5- to 10-fold less potent in the absence of glucose.		Phosphorylase
T13230	TXNIP-IN-1		Others
			Others
T7814	Alloxan monohydrate		Proteasome
	Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.		Proteasome
T13173	TMPA		Others , AMPK
	TMPA is a nuclear receptor Nur77 and LKB1 interaction antagonist.		Others , AMPK
T21729	(±)-Lisofylline		Others
	(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent.		Others
T11845	LGD-6972		Glucagon Receptor
			Glucagon Receptor
T13867	RH01386		Others
	RH01386 is a small molecule that can prevent ER stress-induced β cell dysfunction and death, and inhibits proapoptotic gene expression,has the potential for type 2 diabetes treatment. RH01386 restores ER stress-impaired ...		Others
T8982	RH01687		Others
	RH01687 is a potent β-cell protector , exhibits β-cell-protective activities against endoplasmic reticulum (ER) stress.		Others
T9987	GSK3-IN-1		GSK-3
	GSK3-IN-1 is a GSK3B-glycogen synthase kinase-3 beta inhibitor.		GSK-3
T2701	GSK1292263		GPR
	GSK1292263 is a GPR119 agonist and has been investigated for the treatment of DIABETES MELLITUS, TYPE 2.		GPR
T2042	CTX-0294885		Others
	CTX-0294885, a novel bisanilino pyrimidine, exhibits inhibitory activity against a broad range of kinases in vitro and is further developed into a Sepharose-supported kinase capture reagent.		Others
T8329	AR 231453		GPR
	AR 231453 is a selective and orally available GPR119 agonist,can stimulate β-cell replication and improve islet graft function.		GPR
T14779	BRD7389		SGK , FLT , Pim , CDK , S6 Kinase , DAPK
	BRD7389 is an inhibitor of RSK family kinase with IC50s of 1.5 μM, 2.4 μM, and 1.2 μM for RSK1, RSK2, and RSK3, respectively.		SGK , FLT , Pim , CDK , S6 Kinase , DAPK
T10525	SCD1 inhibitor-4		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	SCD1 inhibitor-4 is stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T9022	AZD9977	AZD 9977	Glucocorticoid Receptor
	AZD9977 is a novel, selective modulator of mineralocorticoid receptor .		Glucocorticoid Receptor
T8975	PSB-SB-487		Cannabinoid Receptor
	PSB-SB-487 is antagonist of GPR55.		Cannabinoid Receptor
T15159	Dorzagliatin	HMS5552	Glucokinase
	Dorzagliatin (HMS5552) is a dual-acting glucokinase (GK) activator. It also improves glycaemic control and pancreatic β-cell function in type 2 diabetes.		Glucokinase
T4628	Seladelpar	MBX 8025	PPAR
	Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.		PPAR
T14327	AS1949490		Phosphatase
	AS1949490 activated glucose metabolism via up-regulation of GLUT1 gene in L6 myotubes[1][2]. AS1949490 is a potent and selective SHIP-2 (SH2 domain-containing inositol 5′ phosphatase 2) inhibitor, with an IC50 of 620 nM.		Phosphatase
T7656	Apelin-13
	Apelin-13 is a 13-amino acid peptide sequence found in the central and peripheral nervous system that is an endogenous ligand for the G protein-coupled receptor angiotensin II protein J (APJ), with an EC50 value of 0.37 ...
T22708	Darglitazone	CP-86325	PPAR
	Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism.		PPAR
T28352	PDE9-IN-(S)-C33	(S)-C33	PDE
	PDE9-IN-(S)-C33 ((S)-C33) is a potent and selective inhibitor of PDE9 (IC50 = 11 nM). PDE9-IN-(S)-C33 can be used for central nervous system diseases and diabetes research.		PDE
T14315	AR-9281	APAU	Epoxide Hydrolase
	AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes		Epoxide Hydrolase
T21694	(R)-Lisofylline	(R)-Lisophylline	STAT
	(R)-Lisofylline ((R)-Lisophylline) is an inhibitor of lysophosphatidic acid acyltransferase (IC50 = 0.6 µM). (R)-Lisofylline interrupts IL-12 signaling-mediated STAT4 activation and can be used in studies about the treat...		STAT
T3978	Linerixibat	GSK2330672,Iinerixibat	HBV
	Linerixibat (GSK2330672) is a highly effective, nonabsorbable ASBT inhibitor (IC50: 42 ± 3 nM). It can lower glucose in an animal model of type 2 diabetes and shows excellent developability properties.		HBV
T2088	APD668	APD 668	GPR , P450 , Potassium Channel
	APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119, respectively.		GPR , P450 , Potassium Channel
T6192	Alogliptin	SYR-322	Ferroptosis , Proteasome , DPP-4
	Alogliptin (SYR-322)(SYR-322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10, 000-fold selectivity over DPP-8 and DPP-9.		Ferroptosis , Proteasome , DPP-4
T4328	OSS_128167	SIRT6-IN-1	HBV , Sirtuin
	OSS_128167 (SIRT6-IN-1) is a specific SIRT6 inhibitor, and for SIRT6(IC50=89 μM), SIRT1(IC50=1578 μM) and SIRT2(IC50=751 μM).		HBV , Sirtuin
T2711	Chembridge-5861528	TCS 5861528	TRP/TRPV Channel
	Chembridge-5861528 (TCS 5861528) is a TRPA1 channel blocker that antagonizes AITC- and 4-HNE-evoked calcium influx with IC50 values of 14.3 and 18.7 μM, respectively.		TRP/TRPV Channel
T8233	BRD3308		Apoptosis , HIV Protease , HDAC
	BRD3308 is a highly selective inhibitor of HDAC3(IC50 of 54 nM), attenuating PE-mediated phosphorylation of ERK but not JNK.		Apoptosis , HIV Protease , HDAC
T21623	AS1269574	AS 1269574	GPR , TRP/TRPV Channel
	AS1269574 is a potent, orally available GPR119 agonist. AS1269574(AS 1269574) has the potential for the research of type 2 diabetes.		GPR , TRP/TRPV Channel
T10492	BD-AcAc 2	Ketone Ester	Reactive Oxygen Species
			Reactive Oxygen Species
T1674	Nateglinide	A4166,Senaglinide	Potassium Channel , Proteasome , PPAR
	Nateglinide (Senaglinide) is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Nateglinide has been linked to rare ins...		Potassium Channel , Proteasome , PPAR
T23521	VULM 1457		Acyltransferase
	VULM 1457 is a potent ACAT inhibitor. VULM 1457 has remarkable hypolipidaemic activity and improves the overall myocardial ischaemia-reperfusion injury outcomes. VULM1457 significantly reduces production and secretion of...		Acyltransferase
T16074	Mifobate	SR-202	PPAR
	Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1].		PPAR
T1162	Acipimox	Olbemox,K-9321	Others
	Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.		Others
T8526	Metformin	1,1-Dimethylbiguanide	Mitophagy , AMPK , Autophagy
	Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability. Metformin may improve glycemic control by increasing insulin sensitivity and decreasing intestinal glucose uptake, and is comm...		Mitophagy , AMPK , Autophagy
T1088	Repaglinide	AG-EE 388 ZW,AG-EE 623ZW	Potassium Channel , PPAR
	Repaglinide (AG-EE 623ZW) is a benzoic acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Repaglinide has been linked to rare instances of clinically appare...		Potassium Channel , PPAR
T5427	GSK1940029	SCD inhibitor 1	Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
	GSK1940029 (SCD inhibitor 1) is a stearoyl-coa desaturase (SCD) inhibitor.		Dehydrogenase , Stearoyl-CoA Desaturase (SCD)
T21867	BI-6015		Others
	BI 6015 is an antagonist of HNF4α. HNF4α is a nuclear receptor that regulates gene expression in the intestine cells, liver cells, and pancreas-β cells.		Others
T0314	Hexylresorcinol	4-Hexylresorcinol	Apoptosis , Tyrosinase , Antibacterial , Parasite
	Hexylresorcinol (4-Hexylresorcinol) is a substituted dihydroxybenzene used topically as an antiseptic for the treatment of minor skin infections.		Apoptosis , Tyrosinase , Antibacterial , Parasite
T0498	Salsalate	Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171	Reactive Oxygen Species , COX
	Salsalate (Sasapyrine) is an orally available salicylate and non-steroidal anti-inflammatory drug (NSAID), with anti-inflammatory, analgesic and antipyretic activities.		Reactive Oxygen Species , COX
T8405	Vardenafil hydrochloride		PDE
	Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes		PDE
T2171	SEW2871	SEW2871	S1P Receptor , LPL Receptor
	SEW 2871 is an orally available, highly selective S1P1 agonist with an EC50 of 13.8 nM.It reduces the number of lymphocytes in the blood and is used in studies related to diabetes, Alzheimer's disease, liver fibrosis, an...		S1P Receptor , LPL Receptor
T0096	Vardenafil	Vivanza,Levitra,Vardenafil hydrochloride	PDE
			PDE
T12883	Fezagepras	PBI-4050,Setogepram	GPR
	Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.		GPR
T2401	Alogliptin Benzoate	SYR 322,Alogliptin(SYR-322)benzoate	Ferroptosis , Proteasome , DPP-4
	Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alogliptin may inhibit inflammatory responses by preventing the...		Ferroptosis , Proteasome , DPP-4
T8780	AMG131	INT-131,AMG-131,CHS 131	PPAR
	AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used for the treatment of type 2 diabetes mellitus (non-insulin depende...		PPAR
T6203	Saxagliptin	BMS-477118,Onglyza	Proteasome , DPP-4
	Saxagliptin (BMS-477118) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.		Proteasome , DPP-4
T0334	Rosiglitazone	BRL49653	Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy
	Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity. Rosiglitazone is also a hypoglycemic agent and a thiazolidinedione insulin sensitizer.		Ferroptosis , TRP/TRPV Channel , PPAR , Autophagy

Compounds

CP-91149

T6455

Synonym:

Target: Phosphorylase

Target: Glucagon Receptor

Target: SGK, FLT, Pim, CDK, S6 Kinase, DAPK

SCD1 inhibitor-4

T10525

Synonym:

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

AZD9977

T9022

Synonym: AZD 9977

Target: Glucocorticoid Receptor

PSB-SB-487

T8975

Synonym:

Target: Cannabinoid Receptor

Target: Epoxide Hydrolase

(R)-Lisofylline

T21694

Synonym: (R)-Lisophylline

Target: STAT

Linerixibat

T3978

Synonym: GSK2330672,Iinerixibat

Target: GPR, P450, Potassium Channel

Alogliptin

T6192

Synonym: SYR-322

Target: Ferroptosis, Proteasome, DPP-4

Target: TRP/TRPV Channel

BRD3308

T8233

Synonym:

Target: Apoptosis, HIV Protease, HDAC

AS1269574

T21623

Synonym: AS 1269574

Target: GPR, TRP/TRPV Channel

BD-AcAc 2

T10492

Synonym: Ketone Ester

Target: Reactive Oxygen Species

Nateglinide

T1674

Synonym: A4166,Senaglinide

Target: Potassium Channel, Proteasome, PPAR

VULM 1457

T23521

Synonym:

Target: Acyltransferase

Synonym: Olbemox,K-9321

Target: Others

Metformin

T8526

Synonym: 1,1-Dimethylbiguanide

Target: Mitophagy, AMPK, Autophagy

Repaglinide

T1088

Synonym: AG-EE 388 ZW,AG-EE 623ZW

Target: Potassium Channel, PPAR

GSK1940029

T5427

Synonym: SCD inhibitor 1

Target: Dehydrogenase, Stearoyl-CoA Desaturase (SCD)

Synonym: 4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

Salsalate

T0498

Synonym: Disalicylic acid,Salicylsalicylic acid,Sasapyrine,NSC-49171

Target: Reactive Oxygen Species, COX

Vardenafil hydrochloride

Target: S1P Receptor, LPL Receptor

Vardenafil

T0096

Synonym: Vivanza,Levitra,Vardenafil hydrochloride

Target: PDE

Fezagepras

T12883

Synonym: PBI-4050,Setogepram

Target: GPR

Alogliptin Benzoate

T2401

Synonym: SYR 322,Alogliptin(SYR-322)benzoate

Target: Ferroptosis, Proteasome, DPP-4

AMG131

T8780

Synonym: INT-131,AMG-131,CHS 131

Target: PPAR

Saxagliptin

T6203

Synonym: BMS-477118,Onglyza

Target: Proteasome, DPP-4

Rosiglitazone

T0334

Synonym: BRL49653

Target: Ferroptosis, TRP/TRPV Channel, PPAR, Autophagy

カタログ番号	製品名	別名	ターゲット
T5809	Stachyose hydrate	Stachyose	Others
	Stachyose hydrate is a natual product,it highly promotes proliferation of lactic acid bacteria (LAB) by inducing LAB to produce more α-galactosidase to hydrolyze stachyose.		Others
T7544	Fucoidan		Others
	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.		Others
TN1403	Arjunolic acid		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
	Arjunolic acid has antioxidant, anti-inflammatory, antinociceptive and anticholinesterasic (AChE and BuChE) activities, it may as promising targets for the development of innovative multi-functional medicines for Alzheim...		IL Receptor , TNF , Reactive Oxygen Species , JNK , AChE
T2210	Genipin	(+)-Genipin	Others , Autophagy
	Genipin ((+)-Genipin), an active aglycone derived from an iridoid glycoside called geniposide, is found in the fruit of Gardenia jasminoides Ellis.		Others , Autophagy
TN1788	Isookanin		Amylase
	Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).		Amylase
T3866	Macelignan	Anwuligan,(+)-Anwulignan	Others , COX
	Macelignan (Anwuligan) is a lignan isolated from nutmeg with antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species.		Others , COX
TN1118	Tormentic acid		Immunology/Inflammation related
	Tormentic acid is a natural product. It has anticancer, anti-inflammatory, anti-atherogenic , anti-allodynic, and hepatoprotective properties,		Immunology/Inflammation related
T0247	Acarbose	BAY g 5421	Glucosidase
	Acarbose (BAY g 5421) is an inhibitor of α-Glucosidases with antihyperglycemic activity.		Glucosidase
T0760	Cholesterol	Cholesterin,Cholesteryl alcohol	Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
	Cholesterol (cholesteryl alcohol) is a natural product that is the major sterol in mammals and an agonist of estrogen-related receptor α (ERRα). Cholesterol is widely found in the cell membranes of animals and is also us...		Estrogen Receptor/ERR , MRP , Endogenous Metabolite , ROR
T4947	3-Hydroxybutyric acid	Butanoic acid	Endogenous Metabolite
	3-Hydroxybutyric acid (Butanoic acid) (or beta-hydroxybutyrate) is a ketone body. Like the other ketone bodies (acetoacetate and acetone), levels of 3-hydroxybutyrate in blood and urine are raised in ketosis. In humans, ...		Endogenous Metabolite
T4723	D-Tagatose	D-(-)-Tagatose,d-tagatos	Others , Endogenous Metabolite
	D-Tagatose (D-(-)-Tagatose), a rare natural hexoketose, is an isomer of d-galactose. D-Tagatose occurs naturally in Sterculia setigera gum, and it is also found in small quantities in various foods such as sterilized and...		Others , Endogenous Metabolite
T3675	1-Deoxynojirimycin	Duvoglustat,Moranoline,moranolin	PI3K , Glucosidase
	1-Deoxynojirimycin (Moranoline) is a potent α-glucosidase inhibitor, suppressing postprandial blood glucose, thereby possibly preventing diabetes mellitus.		PI3K , Glucosidase
T6368	Abscisic Acid	Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）	Others , Proton pump , Endogenous Metabolite
	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.		Others , Proton pump , Endogenous Metabolite
TN1418	Azaleatin		DPP-4
	Azaleatin is a natural product from Rhododendron simsii. Azaleatin is a dipeptidyl peptidase-IV inhibitor. Azaleatin can be used for type-2 diabetes and obesity studies.		DPP-4
TN2144	Resveratroloside		P450 , NO Synthase
	Resveratroloside has cardioprotective effect, it exhibits α±-glucosidase inhibitory activity, it also can inhibit hydroxylation of testosterone by CYP3A4.		P450 , NO Synthase
T4721	β-Nicotinamide mononucleotide	β-NM	Others , Endogenous Metabolite
	β-Nicotinamide mononucleotide (β-NM) is an important intermediate metabolite in the nicotinate and nicotinamide metabolism pathway. Mammals predominantly use nicotinamide rather than nicotinic acid as a precursor for NAD...		Others , Endogenous Metabolite
T21344	1-Deoxynojirimycin hydrochloride	Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin	PI3K , Antibacterial , Antibiotic , Glucosidase
	1-Deoxynojirimycin hydrochloride (Moranoline) is a potent and selective inhibitor of alpha-glucosidase, most commonly found in mulberry leaves. Duvoglustat is used to suppress the elevation of postprandial hyperglycemia.		PI3K , Antibacterial , Antibiotic , Glucosidase
T1273	Diacerein	Diacerhein,Fisiodar,Diacetylrhein	IL Receptor , Interleukin
	Diacerein (Fisiodar) is a prodrug which is metabolized to rhein. It is currently approved in France for the treatment of osteoarthritis although the use of diacerein is restricted due to the side effects including sevre ...		IL Receptor , Interleukin
T13280	Valerylcarnitine	VALERYL-L-CARNITINE	Endogenous Metabolite
	Valerylcarnitine (VALERYL-L-CARNITINE) is a short-chain fatty acid used in the study of type 2 diabetes.		Endogenous Metabolite
T17303	α-Cyclodextrin	Alfadex,NSC269470,NSC 269470,NSC-269470	Others
	α-Cyclodextrin (Alfadex) is a soluble fiber derived from corn and has beneficial effects on weight management in obese individuals with type 2 diabetes.		Others
T5665	Geraniol		Others , Endogenous Metabolite , Antifungal
	geraniol provides a potent protective effect against cardiac dysfunction induced by diabetes. This ameliorative effect could be attributed to its suppression of oxidative stress.		Others , Endogenous Metabolite , Antifungal
T2867	Diosgenin	Nitogenin	STAT
	Diosgenin (Nitogenin) is a spirostan found in DIOSCOREA and other plants. It has favorable effects in the improvement of diabetes and regulation of lipid metabolism.		STAT
TN1499	Cimiracemoside C	Cimicifugoside M	AMPK
	Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.		AMPK
TMS0719	Sequoyitol	5-O-Methyl-Myo-Inositol	Others
	Sequoyitol (5-O-Methyl-Myo-Inositol), a methyl derivative of inositol, is often used to treat diabetes.		Others
TN2277	Torachrysone-8-O-b-D-glucoside	Torachrysone 8-O-glucoside	Antifection
	Torachrysone-8-O-b-D-glucoside shows alpha-glucosidase inhibitory activities, it may be used for the management of type 2 diabetes.		Antifection
T17056	Tetrahydrobiopterin	Sapropterin,BH4,(Rac)-Sapropterin	NOS , Endogenous Metabolite
	Tetrahydrobiopterin (BH4) is a cofactor for aromatic amino acid hydroxylases and an essential cofactor for nitric oxide synthase (NOS), which is used in the study of endothelial dysfunction such as hypertension, hypercho...		NOS , Endogenous Metabolite
T3851	Vicenin 2	Vicenin -2	RAAS
	Vicenin 2 is an angiotensin-converting enzyme (ACE) inhibitor (IC50=43.83 μM) from the aerial parts of Desmodium styracifolium. Vicenin 2 is an inhibitor of α-glucosidase, PTP1B, and RLAR. Vicenin 2 has hepatoprotective,...		RAAS
T7846	Aegeline		Others , Antifungal
	Aegeline is an alkaloidal-amide, isolated from the leaves of Aegle marmelos and have shown antihyperglycemic as well as antidyslipidemic activities in the validated animal models of type 2 diabetes mellitus.		Others , Antifungal
T3403	Glabridin	Q-100692,KB-289522,LS-176045	Reactive Oxygen Species , Tyrosinase , GABA Receptor , Antibacterial , PPAR
	Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on...
T4854	Acetoacetic acid lithium salt	LithoTab acetoacetate,Lithium acetoacetate,Lithium 3-Oxobutyrate	Others , Endogenous Metabolite
	Acetoacetic acid lithium salt (Lithium 3-Oxobutyrate) is a weak organic acid that can be produced in the human liver under certain conditions of poor Metabolism leading to excessive fatty acid breakdown (diabetes mellitu...		Others , Endogenous Metabolite
T13528	Acetoacetic acid sodium salt		Others
	Acetoacetic acid sodium salt is a metabolite of non-esterified fatty acids, involved in the development of human diabetes.		Others
T8071	L-Lysine hydrochloride	Lysine hydrochloride	Virus Protease
	L-Lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, reducing diabetes-related illnesses, increasing calcium absorption and improving gut health.		Virus Protease
T19117	3-Deoxyglucosone	3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose	GPX , Glucagon Receptor
	3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE...		GPX , Glucagon Receptor
T21418	Lisinopril	Linopril,Zestril,Prinivil,Lisipril	RAAS
	Lisinopril (Prinivil), the angiotensin-converting enzyme (ACE) inhibitor, is used primarily in the treatment of high heart failure, blood pressure, and heart attacks. It is also used for preventing eye and kidney complic...		RAAS
T8301	Amaranth	Acid Red 27	Others
	Amaranth (Acid Red 27) as a potential component of lifestyle modification to improve cardiovascular risk profiles by modifying cardiovascular risk factors such as cholesterol, diabetes, and hypertension.		Others
TN1449	Brandioside	2'-O-Acetylpoliumoside,2'-Acetylpoliumoside	Antioxidant
	Brandioside (2'-Acetylpoliumoside), a phenylpropanoid glycoside obtainable from Callicarpa dichotoma Raeuschel, Verbenaceae, has antioxidant activity, attenuates glutamate-induced neurotoxicity, and can be used in the st...		Antioxidant
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside		Others
	Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside		Others
	Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors, α±-glucosidase inhibitors are widely used in the treatment of type 2 diabetes.		Others
T0461L	Berberine sulfate	AI3-61947,Berberin sulfate,Berberine sulphate,Berberal

T5528	Cyanidin Chloride		Antioxidant
	Cyanidin Chloride, the main phenolic antioxidant in the grape (Vitis vinifera), in particular in the liposomal forms, could be used for treatment of diabetes mellitus complications.		Antioxidant
TN1475	Caulophyllogenin	Segetalic acid	IL Receptor , TNF , PPAR , Immunology/Inflammation related
	Caulophyllogenin is a partial PPARγ agonist (EC50 = 12.6 μM) derived from the stem bark of Kalopanax pictus (Araliaceae). Caulophyllogenin inhibits pro-inflammatory cytokine secretion and can be used in studies about the...		IL Receptor , TNF , PPAR , Immunology/Inflammation related
TN1132	Procyanidin A2		IL Receptor , TNF , transporter , Antibacterial
	Procyanidin A2 is a potential precursor of 5-(3',4'-dihydroxyphenyl)-γ-valerolactone, exhibits antioxidant, anti-inflammary, anti-hyperglycemia, and anti-type 2 diabetes activities. Procyanidin A2 demonstrates liver cell...		IL Receptor , TNF , transporter , Antibacterial
TN7079	Coreopsin	Butein-4-O-β-D-glucopyranoside	Others
	Coreopsin(Butein-4-O-β-D-glucopyranoside) is one of the main components from Coreopsis tinctoria Nutt. Flower(CTF). CTF has been used traditionally in China for treating hypertension and diabetes as well as reducing body...		Others
T4322	2-Hydroxybutyric acid	α-Hydroxybutyric acid	Endogenous Metabolite
	2-Hydroxybutyric acid (α-Hydroxybutyric acid) is a product of protein metabolism and a biomarker for type 2 diabetes and pre-eclampsia.		Endogenous Metabolite
T3394	Timosaponin BII	Prototimosaponin A III	Beta Amyloid , Others , BACE
	Timosaponin BII (Prototimosaponin A III) has anti-dementia activity and may be useful for the treatment of type 2 diabetes. Timosaponin BII has antioxidant activity, can inhibit the up-regulation of BACE1 and reduced the...		Beta Amyloid , Others , BACE
TQ0269	Melittoside		Antioxidant
	Melittoside is a natural phenolic glycoside found in the nectar of the Melitto genus. It has antioxidant, anti-inflammatory and antifungal activities, as well as research into its potential use in the treatment of variou...		Antioxidant
T20793	Magnesium Lithospermate B	Monomethyl lithospermate B,Lithospermate B	Others
	Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...		Others
T5S0384	Rhapontin	Ponticin,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside	Apoptosis , Others
	1. Rhapontin (Ponticin) can alleviate liver steatosis and improve blood glucose and lipid profiles in KK/Ay diabetic mice, indicates that rhaponticin has a noticeable antidiabetic effect and could be potentially used as ...		Apoptosis , Others
T1507	Streptozocin	STZ,Streptozotocin,NSC-85998,U 9889	DNA Alkylator/Crosslinker , DNA Alkylation , DNA/RNA Synthesis , Antibacterial , Antibiotic , Autophagy
	Streptozocin (NSC-85998) is an antibiotic that induces DNA methylation. Streptozocin is toxic to insulin-producing pancreatic islet B-cells and is commonly used in the construction of animal models of type 1 diabetes. Th...
T5303	Isethionic acid sodium salt	Sodium isethionate	Others , Endogenous Metabolite
	Isethionic acid sodium salt (Sodium isethionate) is an organosulfur compound containing a short chain alkane sulfonate linked to a hydroxyl group. Mammals are able to endogenously synthesize Isethionic acid sodium salt v...		Others , Endogenous Metabolite
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天然物製品

Target: IL Receptor, TNF, Reactive Oxygen Species, JNK, AChE

Genipin

T2210

Synonym: (+)-Genipin

Target: Others, Autophagy

Synonym: Anwuligan,(+)-Anwulignan

Target: Immunology/Inflammation related

Synonym: Cholesterin,Cholesteryl alcohol

Target: Estrogen Receptor/ERR, MRP, Endogenous Metabolite, ROR

3-Hydroxybutyric acid

T4947

Synonym: Butanoic acid

Target: Endogenous Metabolite

D-Tagatose

T4723

Synonym: D-(-)-Tagatose,d-tagatos

Target: Others, Endogenous Metabolite

1-Deoxynojirimycin

T3675

Synonym: Duvoglustat,Moranoline,moranolin

Target: PI3K, Glucosidase

Abscisic Acid

T6368

Synonym: Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）

Target: Others, Proton pump, Endogenous Metabolite

Target: P450, NO Synthase

β-Nicotinamide mononucleotide

T4721

Synonym: β-NM

Target: Others, Endogenous Metabolite

1-Deoxynojirimycin hydrochloride

T21344

Synonym: Moranoline,AT2220,Duvoglustat hydrochloride,1-Deoxynojirimycin,DNJ,deoxynojirimycin

Target: PI3K, Antibacterial, Antibiotic, Glucosidase

Diacerein

T1273

Synonym: Diacerhein,Fisiodar,Diacetylrhein

Target: IL Receptor, Interleukin

Valerylcarnitine

T13280

Synonym: VALERYL-L-CARNITINE

Target: Endogenous Metabolite

α-Cyclodextrin

T17303

Synonym: Alfadex,NSC269470,NSC 269470,NSC-269470

Target: Others, Endogenous Metabolite, Antifungal

Synonym: Cimicifugoside M

Target: AMPK

Sequoyitol

TMS0719

Synonym: 5-O-Methyl-Myo-Inositol

Target: Others

Torachrysone-8-O-b-D-glucoside

TN2277

Synonym: Torachrysone 8-O-glucoside

Target: Antifection

Tetrahydrobiopterin

T17056

Synonym: Sapropterin,BH4,(Rac)-Sapropterin

Target: NOS, Endogenous Metabolite

Target: Others, Antifungal

Glabridin

T3403

Synonym: Q-100692,KB-289522,LS-176045

Target: Reactive Oxygen Species, Tyrosinase, GABA Receptor, Antibacterial, PPAR

Acetoacetic acid lithium salt

T4854

Synonym: LithoTab acetoacetate,Lithium acetoacetate,Lithium 3-Oxobutyrate

Target: Others, Endogenous Metabolite

Acetoacetic acid sodium salt

T13528

Synonym:

Target: Others

L-Lysine hydrochloride

T8071

Synonym: Lysine hydrochloride

Target: Virus Protease

3-Deoxyglucosone

T19117

Synonym: 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose

Target: GPX, Glucagon Receptor

Lisinopril

T21418

Synonym: Linopril,Zestril,Prinivil,Lisipril

Synonym: 2'-O-Acetylpoliumoside,2'-Acetylpoliumoside

Target: Antioxidant

Chrysin 6-C-arabinoside 8-C-glucoside

TN1487

Synonym:

Target: Others

Chrysin 6-C-glucoside 8-C-arabinoside

Synonym: AI3-61947,Berberin sulfate,Berberine sulphate,Berberal

Synonym: Segetalic acid

Target: IL Receptor, TNF, PPAR, Immunology/Inflammation related

Procyanidin A2

TN1132

Synonym:

Target: IL Receptor, TNF, transporter, Antibacterial

coreopsin

TN7079

Synonym: Butein-4-O-β-D-glucopyranoside

Target: Others

2-Hydroxybutyric acid

T4322

Synonym: α-Hydroxybutyric acid

Target: Endogenous Metabolite

Timosaponin BII

T3394

Synonym: Prototimosaponin A III

Target: Beta Amyloid, Others, BACE

Magnesium Lithospermate B

T20793

Synonym: Monomethyl lithospermate B,Lithospermate B

Target: Others

Rhapontin

T5S0384

Synonym: Ponticin,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside

Target: Apoptosis, Others

Streptozocin

T1507

Synonym: STZ,Streptozotocin,NSC-85998,U 9889

Target: DNA Alkylator/Crosslinker, DNA Alkylation, DNA/RNA Synthesis, Antibacterial, Antibiotic, Autophagy

Isethionic acid sodium salt

T5303

Synonym: Sodium isethionate

Target: Others, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01125	PEA15 Protein, Human, Recombinant	Human	E. coli
	Astrocyticphosphoprotein PEA-15 (PEA15) is a death effector domain (DED)-containing protein. PEA15 is mainly expressed in the central nervous system, principally in astrocytes. Increased PEA15 levels affect tumorigenesis...
TMPY-00395	Insulin Protein, Human, Recombinant	Human	Yeast
	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPY-06935	FGF-21 Protein, Human, Recombinant	Human	E. coli
	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ...
TMPY-02927	RAGE Protein, Human, Recombinant (His)	Human	HEK293
	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02881	RAGE Protein, Human, Recombinant	Human	HEK293
	Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPJ-00071	EPO/Erythropoietin Protein, Human, Recombinant (His)	Human	Human Cells
	Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPY-04699	GAD65 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	Glutamate decarboxylase 2, also known as glutamate decarboxylase 65 kDa isoform, 65 kDa glutamic acid decarboxylase, GAD2 and GAD65, is a member of thegroup II decarboxylase family. GAD2 is identified as a major autoanti...
TMPY-00639	EPO/Erythropoietin Protein, Human, Recombinant (hFc)	Human	HEK293
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00443	EPO/Erythropoietin Protein, Mouse, Recombinant	Mouse	HEK293
	Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-03565	Mannan Binding Lectin/MBL2 Protein, Human, Recombinant	Human	CHO
	MBL (mannose-binding lectin) is primarily a liver-derived collagen-like serum protein, which binds sugar structures on micro-organisms and dying host cells and is one of the four known mediators that initiate activation ...
TMPK-00369	HGF Protein, Human, Recombinant (hFc)	Human	HEK293
	Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different i...
TMPY-00853	IL-1RA Protein, Human, Recombinant	Human	E. coli
	Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-02970	CXCL10 Protein, Human, Recombinant	Human	E. coli
	(C-X-C motif) ligand (CXCL)10 (CXCL10) belongs to the ELR(-) CXC subfamily chemokine. CXCL10/IP-10 exerts its function through binding to chemokine (C-X-C motif) receptor 3 (CXCR3), a seven trans-membrane receptor couple...
TMPY-00907	RBP4 Protein, Human, Recombinant (His)	Human	HEK293
	Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex ...
TMPY-01567	RBP4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Retinol-binding protein 4 (RBP4) is the specific carrier for retinol (also known as vitamin A), and is responsible for the conversion of unstable and insoluble retinol in aqueous solution into stable and soluble complex ...
TMPY-01697	TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-01166	TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)	Human	HEK293
	Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-03101	TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Tumor necrosis factor receptor superfamily, member 1B (TNFRSF1B), also known as Tumor necrosis factor receptor 2 (TNFR2) or CD120b antigen, is a member of the tumor necrosis factor receptor superfamily. TNFR2/CD120b/TNFR...
TMPY-00779	DPP4/CD26 Protein, Human, Recombinant	Human	HEK293
	Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00221	DPP4/CD26 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00778	DPP4/CD26 Protein, Human, Recombinant (hFc)	Human	HEK293
	Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-00122	DPP4/CD26 Protein, Human, Recombinant (His)	Human	HEK293
	Dipeptidyl peptidase-4 (DPP4) or adenosine deaminase complexing protein 2 (ADCP 2) or T-cell activation antigen CD26 is a serine exopeptidase belonging to the S9B protein family that cleaves X-proline dipeptides from the...
TMPY-01146	Insulin Receptor Protein, Human, Recombinant (long isoform, His)	Human	HEK293
	INSR (Insulin receptor), also known as CD22, is a transmembrane receptor that is activated by insulin. INSR belongs to the protein kinase superfamily and exists as a tetramer consisting of two alpha subunits and two beta...
TMPY-01848	HMGB1 Protein, Human, Recombinant (aa 1-215, His)	Human	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-05227	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-02590	HMGB1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	High-mobility group box 1 protein (HMGB1), also known as HMG-1 or amphoterin previously, is a member of the HMGB family consisting of three members, HMGB1, HMGB2, and HMGB3. HMGB1 is a DNA-binding nuclear protein, releas...
TMPY-01621	TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)	Human	HEK293
	Hepatitis A virus cellular receptor 2 (HAVCR2), formerly known as T cell immunoglobulin and mucin domain-3 (TIM-3), is a transmembrane glycoprotein expressed on the surface of terminally differentiated Th1 cells but not ...
TMPY-01167	E-Selectin/CD62E Protein, Human, Recombinant (His)	Human	HEK293
	E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
TMPY-01923	CD25/IL2R alpha Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05644	CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated	Rhesus	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03776	CD25/IL2R alpha Protein, Cynomolgus, Recombinant	Cynomolgus	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-03644	CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05584	CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-05090	CD25/IL2R alpha Protein, Rat, Recombinant (His)	Rat	Baculovirus-Insect Cells
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPY-01103	CD25/IL2R alpha Protein, Human, Recombinant (His)	Human	HEK293
	CD25 (alpha-chain of the IL-2 receptor, or IL2RA), is a type I transmembrane glycoprotein with a signal peptide, an extracellular region, a transmembrane region, and a cytoplasmic domain. IL2RA is expressed on activated ...
TMPK-00075	IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPK-00074	IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I o...
TMPK-00891	GIP Protein, Mouse, Recombinant (His)	Mouse	HEK293
	The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic...
TMPK-00890	GIP Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic...
TMPK-00036	GIP Protein, Human, Recombinant (His)	Human	HEK293
	The potential application of glucose-dependent insulinotropic polypeptide (gastric inhibitory polypeptide, GIP) in the management of obesity and type 2 diabetes has been controversial. Initial interest in the therapeutic...
TMPY-02128	Serpin B1 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	SerpinB1 is an endogenous inhibitor of serine proteases recognized for its anti-inflammatory and host-protective properties. Serum SerpinB1 levels are elevated in patients with type 2 diabetes compared with that in healt...
TMPH-00298	Resistin Protein, Bovine, Recombinant (His)	Bovine	E. coli
	Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.
TMPJ-00742	GCG Protein, Human, Recombinant (His)	Human	Human Cells
	Glucagon is a secreted protein and belongs to the glucagon family. Glucagon can be cleved into 8 chains, playing an important role in initiating and maintaining hyperglycemic conditions in diabetes. Glucagon can regulate...
TMPY-01911	PLA2G1B Protein, Mouse, Recombinant (His)	Mouse	HEK293
	phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein that belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes...
TMPY-01689	PLA2G1B Protein, Human, Recombinant (His)	Human	HEK293
	phospholipase A2, also known as Phosphatidylcholine 2-acylhydrolase 1B, Group IB phospholipase A2, PLA2 and PLA2G1B, is a secreted protein that belongs to the phospholipase A2 family. Phospholipase A2 / PLA2G1B catalyzes...
TMPY-03353	CEL Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	CEL-maturity onset diabetes of the young (MODY), diabetes with pancreatic lipomatosis and exocrine dysfunction, is due to dominant frameshift mutations in the acinar cell carboxyl ester lipase gene (CEL). Bile-salt activ...
TMPJ-01196	ANGPTL8 Protein, Human, Recombinant (hFc)	Human	Human Cells
	The protein specifically promotes pancreatic beta cell proliferation and beta cell mass expansion, thereby improving glucose tolerance. It promotes pancreatic beta cell proliferation without insulin resistance. Also it a...
TMPJ-00014	Resistin Protein, Human, Recombinant (His)	Human	E. coli
	Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPY-05794	FGF-21 Protein, Hamster, Recombinant (His)	Hamster	HEK293
	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ...
TMPY-02139	FGF-21 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes ...
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PEA15 Protein, Human, Recombinant

TMPJ-01125

Species: Human

Expression System: E. coli

Insulin Protein, Human, Recombinant

TMPY-00395

Species: Human

Expression System: Yeast

FGF-21 Protein, Human, Recombinant

TMPY-06935

Species: Human

Expression System: E. coli

RAGE Protein, Human, Recombinant (His)

TMPY-02927

Species: Human

Expression System: HEK293

RAGE Protein, Human, Recombinant

TMPY-02881

Species: Human

Expression System: HEK293

EPO/Erythropoietin Protein, Human, Recombinant (His)

TMPJ-00071

Species: Human

Expression System: Human Cells

GAD65 Protein, Human, Recombinant (GST)

TMPY-04699

Species: Human

Expression System: Baculovirus-Insect Cells

EPO/Erythropoietin Protein, Human, Recombinant (hFc)

TMPY-00639

Species: Human

Expression System: HEK293

EPO/Erythropoietin Protein, Mouse, Recombinant

TMPY-00443

Species: Mouse

Expression System: HEK293

Mannan Binding Lectin/MBL2 Protein, Human, Recombinant

TMPY-03565

Species: Human

Expression System: CHO

HGF Protein, Human, Recombinant (hFc)

TMPK-00369

Species: Human

Expression System: HEK293

IL-1RA Protein, Human, Recombinant

TMPY-00853

Species: Human

Expression System: E. coli

CXCL10 Protein, Human, Recombinant

TMPY-02970

Species: Human

Expression System: E. coli

RBP4 Protein, Human, Recombinant (His)

TMPY-00907

Species: Human

Expression System: HEK293

RBP4 Protein, Mouse, Recombinant (His)

TMPY-01567

Species: Mouse

Expression System: HEK293

TNFR2/CD120b/TNFR1B Protein, Mouse, Recombinant (His)

TMPY-01697

Species: Mouse

Expression System: HEK293

TNFR2/CD120b/TNFR1B Protein, Human, Recombinant (His)

TMPY-01166

Species: Human

Expression System: HEK293

TNFR2/CD120b/TNFR1B Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-03101

Species: Cynomolgus,Rhesus

Expression System: HEK293

DPP4/CD26 Protein, Human, Recombinant

TMPY-00779

Species: Human

Expression System: HEK293

DPP4/CD26 Protein, Mouse, Recombinant (hFc)

TMPY-00221

Species: Mouse

Expression System: HEK293

DPP4/CD26 Protein, Human, Recombinant (hFc)

TMPY-00778

Species: Human

Expression System: HEK293

DPP4/CD26 Protein, Human, Recombinant (His)

TMPY-00122

Species: Human

Expression System: HEK293

Insulin Receptor Protein, Human, Recombinant (long isoform, His)

TMPY-01146

Species: Human

Expression System: HEK293

HMGB1 Protein, Human, Recombinant (aa 1-215, His)

TMPY-01848

Species: Human

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His), Biotinylated

TMPY-05227

Species: Human

Expression System: HEK293

HMGB1 Protein, Mouse, Recombinant (hFc)

TMPY-02590

Species: Mouse

Expression System: HEK293

TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (His)

TMPY-01621

Species: Human

Expression System: HEK293

E-Selectin/CD62E Protein, Human, Recombinant (His)

TMPY-01167

Species: Human

Expression System: HEK293

CD25/IL2R alpha Protein, Mouse, Recombinant (His)

TMPY-01923

Species: Mouse

Expression System: HEK293

CD25/IL2R alpha Protein, Rhesus, Recombinant (His & Avi), Biotinylated

TMPY-05644

Species: Rhesus

Expression System: HEK293

CD25/IL2R alpha Protein, Cynomolgus, Recombinant

TMPY-03776

Species: Cynomolgus

Expression System: HEK293

CD25/IL2R alpha Protein, Cynomolgus, Recombinant (His)

TMPY-03644

Species: Cynomolgus

Expression System: HEK293

CD25/IL2R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-05584

Species: Human

Expression System: HEK293

CD25/IL2R alpha Protein, Rat, Recombinant (His)

TMPY-05090

Species: Rat

Expression System: Baculovirus-Insect Cells

CD25/IL2R alpha Protein, Human, Recombinant (His)

TMPY-01103

Species: Human

Expression System: HEK293

IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)

TMPK-00075

Species: Human

Expression System: HEK293

IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)

TMPK-00074

Species: Mouse

Expression System: HEK293

GIP Protein, Mouse, Recombinant (His)

TMPK-00891

Species: Mouse

Expression System: HEK293

GIP Protein, Mouse, Recombinant (hFc)

TMPK-00890

Species: Mouse

Expression System: HEK293

GIP Protein, Human, Recombinant (His)

TMPK-00036

Species: Human

Expression System: HEK293

Serpin B1 Protein, Human, Recombinant (His)

TMPY-02128

Species: Human

Expression System: Baculovirus-Insect Cells

Resistin Protein, Bovine, Recombinant (His)

TMPH-00298

Species: Bovine

Expression System: E. coli

GCG Protein, Human, Recombinant (His)

TMPJ-00742

Species: Human

Expression System: Human Cells

PLA2G1B Protein, Mouse, Recombinant (His)

TMPY-01911

Species: Mouse

Expression System: HEK293

PLA2G1B Protein, Human, Recombinant (His)

TMPY-01689

Species: Human

Expression System: HEK293

CEL Protein, Mouse, Recombinant (His)

TMPY-03353

Species: Mouse

Expression System: Baculovirus-Insect Cells

ANGPTL8 Protein, Human, Recombinant (hFc)

TMPJ-01196

Species: Human

Expression System: Human Cells

Resistin Protein, Human, Recombinant (His)

TMPJ-00014

Species: Human

Expression System: E. coli

FGF-21 Protein, Hamster, Recombinant (His)

TMPY-05794

Species: Hamster

Expression System: HEK293

FGF-21 Protein, Mouse, Recombinant (His)

TMPY-02139

Species: Mouse

Expression System: HEK293

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カタログ番号	製品名
L1900	Anti-Diabetic Compound Library	683 compounds
	A unique collection of 683 diabetes related compounds;
L5200	Anti-Metabolism Disease Compound Library	1544 compounds
	A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L1510	Nuclear Receptor Compound Library	531 compounds
	A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L2300	Ion Channel Inhibitor Library	931 compounds
	A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;
L1120	AMPK-Targeted Compound Library	80 compounds
	80 well-chosen unique AMPK-targeted small molecules；
L2520	Glycometabolism Compound Library	702 compounds
	702 glycometabolism-related comounds, can be used for HTS and HCT;
L2540	Gut Microbial Metabolite Library	607 compounds
	A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;
L9600	Peptide Compound Library	791 compounds
	791 peptides can be used in peptide drug development and signaling transduction and mechanism study;
L9700	Endoplasmic Reticulum Stress Compound Library	193 compounds
	A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
L2560	Metabolism Compound Library	2320 compounds

L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；
L6750	PBCRBS Traditional Chinese Medicine Compound Library	580 compounds
	A unique collection of 580 compounds derived from traditional Chinese medicines (TCMs) for promoting blood circulation and removing blood stasis.