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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T67755 | Protein kinase G inhibitor-1 | PKA | |
Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM. | |||
T4207 | (S,R,S)-AHPC hydrochloride | VHL Ligand 1 hydrochloride,ULM-1,Protein degrader 1 hydrochloride | Others , Ligand for E3 Ligase |
(S,R,S)-AHPC hydrochloride (Protein degrader 1 hydrochloride) is a building block in the synthesis of proteolysis-targeting chimera technologies (PROTACs). | |||
T4692 | Protein kinase inhibitors 1 hydrochlorid | Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base)) | Others |
Protein kinase inhibitors 1 hydrochlorid (Protein kinase inhibitors 1 hydrochlorid (1365986-44-2(free base))) is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | |||
T40250 | SHP2 protein degrader-1 | SHP2 protein degrader-1 | |
SHP2 protein degrader-1 is a highly efficient allosteric inhibitor targeting SHP2. It effectively induces degradation of SHP2 protein, resulting in cell apoptosis. This compound shows promising potential for studying dis... | |||
T39860 | Protein kinase inhibitors 1 hydrochloride | ||
Protein Kinase Inhibitors 1 Hydrochloride effectively inhibits HIPK2, demonstrating high potency with IC50 values of 136 nM for HIPK1 and 74 nM for HIPK2, alongside a dissociation constant (Kd) of 9.5 nM for HIPK2. | |||
T40272 | KRAS mutant protein inhibitor 1 | ||
KRAS mutant protein inhibitor 1 is a KRAS mutant protein inhibitor for potential treatment in cancer. | |||
T40719 | (Cys47)-HIV-1 tat Protein (47-57) | (Cys47)-HIV-1 tat Protein (47-57) | |
(Cys47)-HIV-1 tat Protein (47-57) possesses membrane translocation functionality and can serve as a surface derivatization agent for magnetic pharmaceuticals, thereby enhancing their uptake into specific target cells. | |||
T4636 | Protein kinase inhibitors 1 | Others , DYRK | |
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM. | |||
T4647 | M2I-1 | M2I 1 | Others |
M2I-1 a small Mad2 inhibitor-1. the first small molecule inhibitor targeting the binding of Mad2 to Cdc20, an essential proteinprotein interaction (PPI) within the SAC. It can disturbs conformational dynamics of Mad2 cri... | |||
TP1229 | β-Amyloid (1-15) | Amyloid β-Protein (1-15) | Beta Amyloid |
β-Amyloid (1-15) (Amyloid β-Protein (1-15)) is a fragment of β-amyloid protein used in the study of Alzheimer's disease. | |||
T14988 | CMPD1 | MAPK | |
CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM). | |||
T77805 | KRAS G12C mutant protein inhibitor A-1 | ||
KRAS G12C mutant protein inhibitor A-1 can be used in studies about Ras. | |||
T2110 | (+)-JQ-1 | JQ1 | Epigenetic Reader Domain , Autophagy , Ligands for Target Protein for PROTAC |
(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility. (+)-JQ-1 induces cell autophagy and inhibits cell proliferation. | |||
TP1149 | HIV-1 Rev (34-50) | HIV-1 Rev 34-50,HIV-1 rev Protein (34-50) | HIV Protease |
HIV-1 Rev (34-50) (HIV-1 rev Protein (34-50)) is a 17 amino acid peptide with anti-HIV-1 activity. HIV-1 Rev (34-50) is derived from the Rev-responsive element-binding domains of Rev in HIV-1. | |||
T9631 | IRAK-4 protein kinase inhibitor 2 | IRAK | |
IRAK-4 protein kinase inhibitor 2 is a potent interleukin-1 receptor-associated kinase-4 (IRAK-4) inhibitor(IC50 = 4 μM). | |||
T12494 | PKC-IN-1 | PKC | |
TP1676L | C-Reactive Protein (CRP) 201-206 acetate | C-Reactive Protein (CRP) 201-206 acetate(130348-99-1 free base) | Others |
C-Reactive Protein (CRP) 201-206 acetate (C-Reactive Protein ) is the 201-206 fragment of C-Reactive Protein. C-Reactive Protein (CRP) acetate, the prototypic marker of inflammation, is a cardiovascular risk marker and m... | |||
T9053 | Lats-IN-1 | Others , YAP | |
Lats-IN-1 is a potent and ATP-competitive Lats1 and Lats2 kinases inhibitor. It promotes Yap-dependent proliferation in postmitotic mammalian tissues. | |||
T16163 | MV1 | Apoptosis | |
MV1 is an antagonist of IAP. When combined with HaloTag ligand, MV1 causes protein knockdown of HaloTag-fused proteins. | |||
T9892 | JAMM protein inhibitor 2 | Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]- | Others |
JAMM protein inhibitor 2 (Acetamide, 2-(2-ethylphenoxy)-N-[2-methyl-4-(1-pyrrolidinyl)phenyl]-) is an inhibitor of JAMM protease and can be used for anticancer studies. The IC50s are 10 μM, 46 μM, and 89 μM for thrombin,... | |||
T11947 | MARK4 inhibitor 1 | Apoptosis , Others , AMPK | |
MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM. | |||
T8764 | PKC-iota inhibitor 1 | PKC | |
PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM) | |||
TP1053L | Protein Kinase C 19-31 acetate | Protein Kinase C 19-31 acetate(121545-65-1 free base),PKC (19-31) acetate | PKC |
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is... | |||
T13230 | TXNIP-IN-1 | Others | |
T13884 | Shield-1 | Others | |
Shield-1 is a specific, high-affinity and cell-permeant ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused protein... | |||
T4442 | MK2-IN-1 hydrochloride | MK2 Inhibitor,MK 25 | MAPK |
MK2-IN-1 hydrochloride (MK 25) is a highly selective, non-ATP competitive inhibitor of p38/mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2 or MK2, IC50: 0.11 μM) [1]. | |||
T5436 | MZ 1 | Epigenetic Reader Domain | |
MZ 1 is a BRD4 protein degrader based on PROTAC technology. | |||
T2352 | AMI-1 | Histone Methyltransferase | |
AMI-1 is an effective and selective Histone Methyltransferase (HMT) inhibitor (IC50: 3.0/8.8 μM, for yeast Hmt1p, and human PRMT1). | |||
T9305 | Necroptosis-IN-1 | RIP kinase | |
Necroptosis-IN-1 is a potent necroptosis inhibitor of RIPK1. It is an analog of Necrostatin-1. | |||
T1919 | Tenovin-1 | Tenovin 1 | Mdm2 , Dehydrogenase , Sirtuin , p53 , Autophagy |
Tenovin-1 inhibits protein-deacetylating activities of SirT1 and SirT2 and protects against MDM2-mediated p53 degradation, which involves ubiquitination. | |||
T10359 | AR antagonist 1 | Androgen Receptor , Ligand for E3 Ligase , Ligands for Target Protein for PROTAC | |
AR antagonist 1 is a potent antagonist of the androgen receptor. It binds to E3 ligase ligands with weak binding affinities to VHL protein in the synthesis of PROTAC ARD-266. | |||
T14860 | CaMKII-IN-1 | CaMK , Autophagy | |
CaMKII-IN-1 is a potent and highly selective CaMKII inhibitor (IC50: 63 nM). It has significantly high selectivity against CaMKIV, p38a, MLCK, Akt1, and PKC. | |||
T12562 | Protein kinase affinity probe 1 | Others | |
Protein kinase affinity probe 1 is a protein kinase affinity probe for the functional identification of protein kinases (PKs). | |||
T1847 | Necrostatin-1 | Nec-1,Necrostatin 1 | Indoleamine 2,3-Dioxygenase (IDO) , Ferroptosis , Autophagy , RIP kinase |
Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity. Necrostatin-1 inhibits TNF-α-induced necrotic apoptosis. Necrostatin-1 also inhibits IDO. | |||
T3346 | AKT inhibitor VIII | AKTi-1/2 | Apoptosis , Akt |
AKT inhibitor VIII (AKTi-1/2) is a highly specific Akt1/2 inhibitor (IC50: 58/210 nM). The selectivity for Akt1 is higher about 36-fold than Akt3. | |||
T8788 | Naptalam | Others | |
Naptalam is an herbicide.Naptalam is a dicarboxylic acid monoamide which results from addition of one equivalent of 1-naphthylamine to phthalic anhydride. It is a dicarboxylic acid monoamide, a carboxylic acid and a N-(1... | |||
T5416 | T-5224 | MMP | |
T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. | |||
T8969 | API-1 | NSC177223 | Akt |
API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis . | |||
T14960 | Chroman 1 | ROCK | |
Chroman 1 is an inhibitor of ROCK2 (IC50: 1 nM). | |||
T12341 | P-gp inhibitor 1 | Others , P-gp | |
T4468 | WAY 316606 | Wnt/beta-catenin | |
WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. | |||
T9079 | Apostatin-1 | Apt-1 | Others |
Apostatin-1 (Apt-1) is a novel TRADD inhibitor. Apostatin-1 can bind to a pocket on the N-terminal TRAF2 binding domain of TRADD. | |||
T8596 | Ceefourin 1 | MRP | |
Ceefourin 1 is a highly selective multidrug resistance protein 4 (MRP4) inhibitor. | |||
T7428 | SBI-115 | GPCR19 | |
SBI-115 is an antagonist of TGR5. SBI-115 decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5 | |||
T9349 | IXA4 | IRE1 | |
IXA4 is a highly selective, nontoxic activator of IRE1/XBP1s and reduces APP secretion by activating IRE1. IXA4-stimulated IRE1 activation also enhanced pancreatic function. | |||
T9174 | Icerguastat | Sephin 1,lcerguastat,IFB-088 | Phosphatase |
Icerguastat (IFB-088) is a selective inhibitor of holophosphatase. Sephin1 safely and selectively inhibited a regulatory subunit of protein phosphatase 1 in vivo. | |||
T13244 | Ubiquitination-IN-1 | Others | |
T4083 | BAR501 | BAR 501 | GPCR19 |
BAR501 is an effective and specific GPBAR1 agonist (EC50: 1 μM). | |||
T8376 | PKCβ inhibitor 1 | KUN79359 | Apoptosis , PKC |
PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2, respectively). | |||
T23384 | SR 11302 | DNA/RNA Synthesis | |
SR 11302 is an inhibitor of activator protein-1 (AP-1). |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1136 | Procyanidin A1 | Proanthocyanidin A1 | LDL , Calcium Channel , PKC |
Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+; influx from an internal store in RBL-2H3 cells. | |||
T2851 | Daphnetin | 7,8-Dihydroxycoumarin,Daphnetol | EGFR , PKA , PKC , Parasite , Autophagy |
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-... | |||
T5077 | Deoxycholic acid sodium salt | Sodium deoxycholate,Sodium Desoxycholate | Endogenous Metabolite , GPCR19 |
Deoxycholic acid sodium salt (Sodium deoxycholate) can activate the G protein-coupled bile acid receptor TGR5 that stimulates brown adipose tissue (BAT) thermogenic activity. | |||
T3002 | Piperine | 1-Piperoylpiperidine,Bioperine | P450 , Endogenous Metabolite , P-gp , Autophagy |
Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders. | |||
TN1651 | Furanodiene | Apoptosis , PARP , Reactive Oxygen Species , Caspase , CDK , P-gp | |
Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans. | |||
T3S0012 | Coniferyl ferulate | P-gp , GST | |
Coniferyl ferulate is a strong inhibitor of glutathione S-transferase (GST) isolated from Radix Angelicae sinensis. It shows strong inhibition of human placental GST (IC50: 0.3 μM). It also reverses multidrug resistance ... | |||
T2965 | Deoxycholic acid | Cholorebic,Deoxycholate,Desoxycholic acid,Cholanoic Acid,Cholerebic | Endogenous Metabolite , GPCR19 |
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorptio... | |||
T0700 | Ursodeoxycholic acid | UDCA,Ursodiol | Potassium Channel , Endogenous Metabolite |
Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption. | |||
T5552 | Methyl cinnamate | Tyrosinase , Antibacterial , AMPK | |
Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects. | |||
T3895 | Polyphyllin I | Apoptosis , Akt , JNK , PDK , mTOR , Autophagy | |
Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D ha... | |||
T0895 | Oxytetracycline | Terramycin | ribosome , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions. | |||
T2S0223 | Isosinensetin | 6-Demethoxynobiletin | Antioxidant , HIV Protease , Antibacterial , P-gp |
1. Isosinensetin (6-Demethoxynobiletin) shows antioxidant and HIV-1 protease inhibiting activities. | |||
T2968 | Hyodeoxycholic acid | NSC 60672,α-Hyodeoxycholic Acid,HDCA | FXR , Endogenous Metabolite , GPCR19 |
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia. | |||
TN4761 | Phellamurin | P-gp | |
Phellamurin inhibits intestinal P-glycoprotein in a dose-dependent manner, there is a serious interaction occurred between Phellamurin with cyclosporin, to ensure the efficacy of cyclosporin, we suggest that the coadmini... | |||
T2P2806 | Hederacolchiside A1 | Raddeanoside R13 | Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR |
Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol... | |||
TJS1159 | Chrysosplenetin | Chrysosptertin B | P450 , Ferroptosis , P-gp |
Chrysosplenetin is a metabolic inhibitor of artemisinin. | |||
T2S0271 | Voacamine | Voacanginine | Cannabinoid Receptor , P-gp |
Voacamine (Voacanginine) is an indole alkaloid. Voacamine exhibits potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells.Voacangini... | |||
T2S1200 | Sinapine | Antioxidant , P-gp , AChE | |
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant and radio-protective activities. | |||
T5736 | 1,3-Dicaffeoylquinic acid | CYNARIN,Cyclohexanecarboxylic acid, 1,3-bis[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-4,5-dihydroxy-, (1S,3R,4R,5R)-,1,3-O-Dicaffeoylquinic acid,1,5-Dicaffeoylquinic acid | Reactive Oxygen Species , Akt , PI3K |
1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent. | |||
T4034 | Solamargine | Solamargin,δ-Solanigrine | Apoptosis , p38 MAPK , P-gp , STAT |
Solamargine (δ-Solanigrine) is a major steroidal alkaloid glycoside extracted from a traditional Chinese medicine herb, Solanum nigrum L. (SNL); has been shown to inhibit growth and induce apoptosis of various cancer cel... | |||
T3392 | Sinapine thiocyanate | P-gp , AChE | |
Sinapine Thiocyanate, is a derivative of Sinapine (S486605), an alkaloidal amine found in black mustard seeds. It is the choline ester of Sinapic Acid (S486800). It is also a phenolic-chloine conjugates, acting as anti-o... | |||
T6624 | Oxytetracycline Dihydrate | Terramycin Dihydrate | Others , Endogenous Metabolite , Antibacterial , Antibiotic , HSV |
Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins. | |||
T4085 | Paris saponin VII | Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII | Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy |
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation. | |||
T29078 | Ursodeoxycholic acid sodium | UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium | FXR , Endogenous Metabolite , GPCR19 |
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it... | |||
T2799 | (20S)-Protopanaxadiol | 20-Epiprotopanaxadiol,20(S)-APPD | Apoptosis , Reactive Oxygen Species , P-gp |
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) (20-Epiprotopanaxadiol), an apoptosis inducer, is an aglycon metabolic derivative of the protopanaxadiol-type ginseng saponin. | |||
T1205 | Chloramphenicol | Chlornitromycin,Levomycetin,Chloromycetin | ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic |
Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis. | |||
TN1757 | Hypophyllanthin | Potassium Channel , Calcium Channel , P-gp | |
Hypophyllanthin and phyllanthin have antitumour effects against Ehrlich Ascites Carcinoma in mice. | |||
TN1525 | Convallatoxin | NF-κB , P-gp , PPAR | |
Convallatoxin is a natural product | |||
T21430 | Oxytetracycline Hydrochloride | Biosolvomycin,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin | Antiviral , Endogenous Metabolite , Antibacterial , HSV |
Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resultin... | |||
TCS2336 | Evodine | P-gp | |
1. Evodine has antinociceptive activity. | |||
T4839 | Ac-Ala-OH | N-Acetylalanine,N-Acetyl-L-alanine | Others , Endogenous Metabolite |
Ac-Ala-OH (N-Acetyl-L-alanine) is a substrate for Guanine nucleotide-binding protein G(I)/G(S)/G(O) gamma-2 subunit, Myelin basic protein, GTP-binding nuclear protein Ran, Tropomyosin alpha 4 chain, HIV-1 Rev binding pro... | |||
T5530 | Mithramycin A | Plicamycin | DNA/RNA Synthesis |
Mithramycin A (Plicamycin), a DNA-binding antitumor antibiotic, is a selective specificity protein 1 (Sp1) inhibitor, which inhibits the growth of various cancers by decreasing Sp1 protein. Specificity protein 1 (Sp1) is... | |||
T3S1729 | Dihydrolycorine | Others | |
1. Dihydrolycorine-HCL(DL) shows hypotensive effects, it can block alpha 1-adrenoceptors. 2. Dihydrolycorine is an inhibitors of protein synthesis in eukarytic cells, it halts protein synthesis in eukaryotic cells by inh... | |||
T4934 | 1-Methyl-L-histidine | 3-(1-Methylimidazol-4-yl)-L-alanine,Nτ-Methyl-L-histidine | Endogenous Metabolite |
1-Methyl-L-histidine (3-(1-Methylimidazol-4-yl)-L-alanine) is a natural but non-proteinogenic amino acid; employed as index of muscle protein breakdown. | |||
T3892 | Isoacteoside | Isoverbascoside | NF-κB |
Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. | |||
T40490 | Phenylalanylalanine | H-Phe-Ala-OH | Others |
Phenylalanylalanine (H-Phe-Ala-OH) (H-Phe-Ala-OH) is a dipeptide resulting from the fusion of phenylalanine and alanine. It is formed during incomplete protein digestion or catabolism [1]. | |||
T4S0795 | Berberrubine chloride | 9-Berberoline Chloride,Beroline,Beroline Chloride,Berberrubine,9-Berberoline | IL Receptor |
1. Berberrubine chloride (9-Berberoline Chloride) has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expressio... | |||
T6S0095 | Genkwanin | 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether | Virus Protease |
1. Genkwanin (Apigenin 7-methyl ether) exerts its anti-inflammatory effect mainly through the regulation of the miR-11/MKP-1/MAPK pathway. 2. Genkwanin is transported by both passive diffusion and multidrug resistance pr... | |||
TN5171 | Tricetin | Apoptosis , Others , Nrf2 | |
Tricetin is a flavonoid isolated from pomegranate.Tricetin is a potent competitive inhibitor of Keap1-Nrf2 protein-protein interaction (PPI) and protects Parkinson's disease patients from 6-OHDA-induced neurotoxicity by ... | |||
T6S2023 | Harpagoside | Others , COX , NO Synthase | |
1. Harpagoside has anti-inflammatory activity. 2. Harpagoside at 3 mM concentration, shows moderate inhibition of seed germination. 3. Harpagoside can inhibit lipopolysaccharide-induced mRNA levels and protein expression... | |||
TN2190 | Scoulerine | Apoptosis , Beta-Secretase , BACE , Parasite | |
Scoulerine is an inhibitor of ß-site amyloid precursor protein cleaving enzyme 1(BACE1). Scoulerine a potent antimitotic compound that inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells. | |||
T6S1780 | Protosappanin B | Q-100961,FT-0689654 | Apoptosis |
1. Protosappanin B (Q-100961) significantly increases cell viability, inhibits cell apoptosis and up-regulates the expression of growth-associated protein 43. 2. Protosappanin B induces the degradation of p53 protein, vi... | |||
TP2167 | β-CGRP, human acetate | β-CGRP, human acetate (101462-82-2 free),CGRP-II (Human) (acetate),Human β-CGRP acetate | CGRP Receptor |
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptor (CRLR) (IC50s: 1 nM and 300 nM for CRLR/RAMP1 and CRLR/RAMP... | |||
T4868 | Gamma-Linolenic acid | gamolenic acid,γ-Linolenic acid | Endogenous Metabolite |
gamma-Linolenic acid (gamolenic acid), is an unsaturated fatty acid synthesized from linoleic acid (LA) by the enzyme delta-6-desaturase. Research on hepatocellular cell lines has shown γ-Linolenic Acid to have induced r... | |||
T6S0052 | Chelerythrine | Toddalin,Broussonpapyrine,Cheleritrine | Apoptosis , BCL , PKC , Autophagy |
1. Chelerythrine (Broussonpapyrine) may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiprolifera... | |||
T6S1141 | Ganoderic acid A | Apoptosis , NF-κB , Endogenous Metabolite , Autophagy | |
1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis a... | |||
T19117 | 3-Deoxyglucosone | 3-Deoxy-D-glucosone,2-keto-3-Deoxyglucose | GPX , Glucagon Receptor |
3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein amino groups to form advanced glycosylated end proteins (AGE... | |||
T30969 | Clitocine | Apoptosis , BCL | |
Clitocine, an adenosine analogue derived from mushrooms, is a potent transcriptional readout agent, an inhibitor of nonsense mutations, and has anticancer activity, inducing the production of p53 protein in cells carryin... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-02882 | HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) | HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.2 kDa. | |||
TMPJ-00412 | VEGFR1/FLT-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ... | |||
TMPJ-00850 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) | Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-03835 | CDCP1 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
CDCP1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.4 kDa and the accession number is F6TPM5. | |||
TMPY-05840 | IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 Cells |
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1. | |||
TMPY-03363 | C-Reactive Protein Protein, Human, Recombinant | Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-04125 | PTP1B Protein, Human, Recombinant (His) | Human | E. coli |
PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c... | |||
TMPY-01815 | FOLR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A0A024R5H1. | |||
TMPY-03432 | KEAP1 Protein, Human, Recombinant | Human | Baculovirus Insect Cells |
KEAP1 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 69.7 kDa and the accession number is Q14145. | |||
TMPY-02101 | KEAP1 Protein, Human, Recombinant (His & GST & Avi) | Human | Baculovirus Insect Cells |
KEAP1 Protein, Human, Recombinant (His & GST & Avi) is expressed in Baculovirus insect cells with His, GST and Avi tag. The predicted molecular weight is 99.2 kDa and the accession number is Q14145. | |||
TMPY-05593 | IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1. | |||
TMPY-01253 | LAMP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
LAMP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A0A024RDY3. | |||
TMPY-03888 | KEAP1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
KEAP1 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 97.37 kDa and the accession number is A0A024R7C0. | |||
TMPY-02295 | IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) | Human | HEK293 Cells |
IGFBP-7 Protein, Human, Recombinant (aa 1-282, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53.5 kDa and the accession number is Q16270. | |||
TMPK-00114 | C-Reactive Protein /CRP Protein, Human, Recombinant (His) | Human | HEK293 Cells |
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ... | |||
TMPY-02632 | SIRP alpha Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
SIRP alpha Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is BAA20376.1. | |||
TMPY-04298 | CDCP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3. | |||
TMPY-06051 | SIRP alpha Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1. | |||
TMPY-01573 | SIRP alpha Protein, Human, Recombinant (G75A, His) | Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-01813 | ACRV1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the a... | |||
TMPY-06052 | SIRP alpha V2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SIRP alpha V2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is AAH38510.1. | |||
TMPY-04580 | IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
IL-1RAP/IL-1RAcP Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.7 kDa and the accession number is Q3UEL3. | |||
TMPY-02443 | HSP70 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
HSP70 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 72.2 kDa and the accession number is A8K5I0. | |||
TMPY-01461 | EMAP-II/AIMP1 Protein, Human, Recombinant (His) | Human | E. coli |
EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1. | |||
TMPY-01156 | ULBP-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
ULBP-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.8 kDa and the accession number is Q9BZM6. | |||
TMPJ-00811 | IGFBP-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Insulin-like growth factor-binding protein 1 (IGFBP1) is encoded by 259 amino acid (aa) with 25 aa residue signal peptide that is processed to generate the 234 aa residue mature protein. IGF-binding proteins prolong the ... | |||
TMPY-03565 | Mannan Binding Lectin/MBL2 Protein, Human, Recombinant | Human | CHO Cells |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 24 kDa and the accession number is P11226. | |||
TMPY-01405 | ULBP-1 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
ULBP-1 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 50.4 kDa and the accession number is Q9BZM6. | |||
TMPJ-00930 | VCAM-1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1... | |||
TMPK-01144 | Kremen-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
KREMEN1 (KRM1) has been identified as a functional receptor for Coxsackievirus A10 (CV-A10), a causative agent of hand-foot-and-mouth disease (HFMD), which poses a great threat to infants globally. KRM1 selectively binds... | |||
TMPY-05525 | Art v 1 Protein, Artemisia vulgaris, Recombinant (His) | Artemisia vulgaris | HEK293 Cells |
Art v 1 Protein, Artemisia vulgaris, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is Q84ZX5.1. | |||
TMPY-01408 | HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) | HIV | HEK293 Cells |
HIV-1 (group M, subtype CRF07_BC) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 98 kDa. | |||
TMPY-00426 | HIV-1 (group P, strain RBF168) gp140 Protein (hFc) | HIV | HEK293 Cells |
HIV-1 (group P, strain RBF168) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.4 kDa and the accession number is D0VTQ8. | |||
TMPY-05591 | ULBP-1 Protein, Human,Recombinant(aa 1-216, His&AVI),Biotinylated | Human | HEK293 Cells |
ULBP-1 Protein, Human,Recombinant(aa 1-216, His&AVI),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 25.6 kDa and the accession number is Q9BZM6. | |||
TMPY-04144 | Kremen-1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
KREMEN1 (Kringle Containing Transmembrane Protein 1) is a Protein Coding gene. This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (... | |||
TMPH-01029 | CAPN1 Protein, Human, Recombinant (His) | Human | E. coli |
Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His... | |||
TMPY-00080 | IGFBP-1 Protein, Canine, Recombinant (His) | Canine | HEK293 Cells |
IGFBP-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is A0A8C0MZD6. | |||
TMPH-00460 | Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) | Dahlia merckii | E. coli |
Defensin-like protein 1 Protein, Dahlia merckii, Recombinant (B2M & His) is expressed in E. coli. | |||
TMPY-02920 | IGFBP-1 Protein, Rhesus, Recombinant (His) | Rhesus | HEK293 Cells |
IGFBP-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A0A1D5QTL3. | |||
TMPJ-00147 | FOLR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
FOLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-75 kDa and the accession number is P15328. | |||
TMPY-00425 | HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) | HIV | HEK293 Cells |
HIV-1 (group M, subtype A, strain 92UG037.1) gp140 Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 97.4 kDa and the accession number is P90249. | |||
TMPH-01036 | Caprin-1/CAPRIN1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types. Binds directly and selectively to MYC and CCND2 RNAs... | |||
TMPY-00361 | Pellino-1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
PELI is a family of E3 ubiquitin ligases that regulate protein activity through a post-translational modification, ubiquitination. PELI1 may function to control inadvertent activation of RIP3, thus preventing aberrant ce... | |||
TMPY-04871 | HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) | HIV | HEK293 Cells |
HIV-1 (group M, subtype C, strain 92BR025) gp140 Protein (Fc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 99.9 kDa and the accession number is O12164. | |||
TMPY-02043 | PARK7/DJ-1 Protein, Human, Recombinant (His) | Human | E. coli |
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress.... | |||
TMPJ-00252 | SIRP beta 1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Signal-regulatory protein beta-1 (SIRPB1, CD172b) is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glyco... | |||
TMPY-02836 | MFGE8 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1. | |||
TMPH-01012 | BMP-1 Protein, Human, Recombinant (His) | Human | E. coli |
BMP-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 102.0 kDa and the accession number is P13497. | |||
TMPY-04572 | MKK4 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus Insect Cells |
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell pr... | |||
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