検索結果

Search Results for " anti-proliferation "

ターゲット

Androgen Receptor

135

阻害剤

天然化合物

100

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T6400	AZD3514		Androgen Receptor
	AZD3514 is a potent and oral androgen receptor downregulator with Ki of 2.2 μM and has ability of reducing AR protein expression.Phase 1.		Androgen Receptor
T8839	ICCB280		Apoptosis , Others
	ICCB280 was capable of inducing differentiation and apoptosis of ATRA-resistant patient blasts strongly signify that the activity of this compound can overcome resistance to other current therapies for AML with an unfavo...		Apoptosis , Others
T11285	FIDAS-5		Others
	FIDAS-5, a potent and orally active methionine S-adenosyltransferase 2A (MAT2A) inhibitor with an IC50 of 2.1 μM, competitively inhibits S-adenosylmethionine (SAM) binding to MAT2A. It exhibits anticancer activities.		Others
T11284	FIDAS-3		Others , Wnt/beta-catenin , Methionine Adenosyltransferase (MAT)
	FIDAS-3, a stilbene derivative and potent Wnt inhibitor with an IC50 of 4.9 μM for methionine S-adenosyltransferase 2A (MAT2A), exhibits anticancer activities by effectively competing with S-adenosylmethionine (SAM) for ...
T7138	FB23-2		Apoptosis , Others
	FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).		Apoptosis , Others
T13996	1-Naphthohydroxamic acid		HDAC
	1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC50 of 14 μM, and it is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC50 >100 μM). 1-Naphthohydroxamic acid d...		HDAC
T1923	BRD4770		Histone Methyltransferase
	BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.		Histone Methyltransferase
T8872	(Rac)-JBJ-04-125-02	JBJ-04-125-02	EGFR
	(Rac)-JBJ-04-125-02 (JBJ-04-125-02) is effective as a single agent in both in vitro and in vivo models of EGFR-mutant lung cancer.		EGFR
T9195	SHR0302	ARQ252	Apoptosis , JAK
	SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3, 420 times for Tyk2).		Apoptosis , JAK
T1995	Fedratinib	TG-101348,SAR 302503	Apoptosis , FLT , c-RET , JAK
	Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.		Apoptosis , FLT , c-RET , JAK
T2680	NVP-BVU972		c-Met/HGFR
	NVP-BVU972 is a selective and potent Met inhibitor with IC50 of 14 nM.		c-Met/HGFR
T5168	EGFR-IN-12	EGFR Inhibitor	Apoptosis , EGFR
	EGFR-IN-12 (EGFR Inhibitor) is a cell permeable and selective inhibitor of EGFR kinase (IC50: 21 nM) and blocks receptor autophosphorylation in cells.		Apoptosis , EGFR
T3661	Citarinostat	ACY241,HDAC-IN-2	HDAC
	ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...		HDAC
T23127	PD-161570	PD 161570	EGFR , FGFR , PDGFR , Src
	PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...		EGFR , FGFR , PDGFR , Src
T9251	Fedratinib hydrochloride hydrate	TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate	Apoptosis , JAK
	Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.		Apoptosis , JAK
T2028	NG 52	NG52,NG-52,Compound 52	CDK
	NG 52 (NG-52) is a cell-permeable, reversible, and ATP-compatible inhibitor of the cell cycle-regulating kinase Cdc28p and the related Pho85p kinase.		CDK
T2275	YK-4-279		Apoptosis , DNA/RNA Synthesis
	YK 4-279, an inhibitor of RNA Helicase A (RHA), binds to the oncogenic transciption factor EWS-FLI1.		Apoptosis , DNA/RNA Synthesis
T5994	KPT-6566		Others
	KPT-6566 is a novel selective covalent pin1 inhibitor, KPT-6566 shows an IC50 of 640 nM and a Ki of 625.2 nM for PIN1 PPIase domain,and has anti-cancer activity.		Others
T2690	Tranilast	MK 341,SB 252218	RAAS , Prostaglandin Receptor
	Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.		RAAS , Prostaglandin Receptor
T8867	RO2959 Hydrochloride	RO2959 HCl	IL Receptor , Calcium Channel , Interleukin
	RO2959 Hydrochloride (RO2959 HCl) is a potent and selective inhibitor of CRAC channel(IC50: 402 nM). It is also a potent inhibitor of human IL-2.		IL Receptor , Calcium Channel , Interleukin
T3146	BMS-202	PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2	Apoptosis , PD-1/PD-L1
	BMS-202 (PD1-PDL1 inhibitor 2) is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand 1) protein/protein interaction.		Apoptosis , PD-1/PD-L1
T6835	Fenoldopam mesylate	Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526	Dopamine Receptor
	Fenoldopam mesylate (Corlopam mesylate) is a selective dopamine-1 receptor (DA1) agonist with natriuretic/diuretic properties. It lowers blood pressure through arteriolar vasodilation.		Dopamine Receptor
T20792	W-7 hydrochloride	W 7 HCl,W7 HCl,W-7 HCl	CaMK , Apoptosis , Myosin , PDE
	W-7 hydrochloride (W-7 HCl), a calmodulin antagonist, inhibits Ca2+-calmodulin-dependent myosin light chain kinase and phosphodiesterase, W-7 hydrochloride induces apoptosis and has antitumor activity.		CaMK , Apoptosis , Myosin , PDE
T23480	U-83836E		Others
	U-83836E (lazaroid ) has neuroprotective activity and anti-tumor activity, inhibits glioma cell proliferation, inhibits tumor necrosis factor and reverses endotoxin-induced shock.		Others
T60102L	Dimethylaminomicheliolide HCl		PKM
	Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvate kinase 2 (PKM2) and reconnecting aerobic cell populations.		PKM
T33701	NM-3	NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3	Apoptosis , Reactive Oxygen Species
	NM-3 is an orally available anti-angiogenic inhibitor with anti-tumour activity.NM-3 is used as a radiation modulator in vitro and in vivo.NM-3 inhibits vascular endothelial growth factor (VEGF), thereby inhibiting the p...		Apoptosis , Reactive Oxygen Species
T5351L	PU-WS13 hydrobromide	PU-WS13 hydrobromide (1454619-14-7 Free base)	GPR
	PU-WS13 hydrobromide is a GRP94 inhibitor with anti-inflammatory activity and inhibits the proliferation of M2-like macrophages in mouse TNBC tumors.		GPR
T25214	CCR-11	CCR11,CCR 11	Antibiotic
	CCR-11 is a tannin-containing derivative with antimicrobial activity. CCR-11 inhibits the proliferation of B. subtilis and HeLa cells. CCR-11 inhibits bacterial proliferation and bacterial cytoplasmic division by inhibit...		Antibiotic
T0740	Metformin hydrochloride	Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride	Mitophagy , AMPK , Autophagy
	Metformin hydrochloride (1,1-Dimethylbiguanide hydrochloride) , a widely used anti-diabetic drug, has a potential function as an anti-Y medicine. It inhibits the proliferation of a variety of Y cells including colon, pro...		Mitophagy , AMPK , Autophagy
T78212	KRAS G12D inhibitor 18	KRAS G12D IN 18	Others
	KRAS G12D inhibitor 18 is a potent KRAS G12D inhibitor with potential anti-tumor and inhibitory activity against tumor cell proliferation for the study of pancreatic cancer.		Others
T60269	ZINC194100678		PAK
	ZINC194100678 is an effective PAK1 inhibitor with IC50 of 8.37μM. ZINC194100678 showed strong anti-proliferation activity, with IC50 value of 40.16μM against MDA-MB-231.		PAK
T4184	NSC 409012	5-(4-iodobenzylidene)rhodanine	Others
	NSC-409012 (5-(4-iodobenzylidene)rhodanine) is an active compound that has been found to have a variety of biochemical and physiological effects, including regulation of gene expression, cell proliferation and apoptosis....		Others
T67746	IMS2186		Others
	IMS2186 is a reagent with activity of antichoroidal neovascularization (CNV). IMS2186 could arrest cancer cell cycle in G2/M phase, result in exerting anti-proliferation and anti-angiogenesis effects. IMS2186 reduces the...		Others
TQ0081	JPH203	KYT-0353	Others
	JPH203 (KYT-0353) is a potent and specific inhibitor of L-type amino acid transporter protein 1 (LAT-1). JPH203 inhibits cellular uptake of leucine, inhibits cell proliferation, induces apoptosis, and possesses anti-infl...		Others
T67899	Topoisomerase II inhibitor 13		Topoisomerase
	Topoisomerase II inhibitor 13 inhibits topoisomerase II (Topo II) that shows strong anti-proliferation activity against HL-60/MX2 cancer cells derived from HL-60 against Topo II toxicity.		Topoisomerase
T9468	FR054		Others
	FR054 is an inhibitor of the Hexosamine Biosynthetic Pathway (HBP) enzyme PGM3, with a remarkable anti-breast cancer effect. FR054 induces in different breast cancer cells a dramatic decrease in cell proliferation and su...		Others
T76781	Itolizumab	EQ-001	Others
	Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti...		Others
T6891	MK-4101		Apoptosis , Hedgehog/Smoothened , Smo
	MK-4101, an effective inhibitor of the Hedgehog pathway, has anti-tumor activity through the induction of extensive apoptosis and inhibition of proliferation in tumor cells.		Apoptosis , Hedgehog/Smoothened , Smo
T76796	Patritumab	U3-1287,AMG-888	ERK , EGFR , Akt , HER
	Patritumab (U3-1287) is an anti-HER3 monoclonal antibody with potential antitumor activity and inhibits phosphorylation of EGFR, HER2, HER3, ERK, and AKT.Patritumab promotes apoptosis and inhibits proliferation in non-sm...		ERK , EGFR , Akt , HER
T17208	USL311		CXCR
	USL311 is a CXCR4 receptor antagonist which prevents the binding of stromal-cell derived factor-1 (SDF-1 or CXCL12) to CXCR4. USL311 inhibits CXCR4 activation and decreases proliferation and migration of CXCR4-expressing...		CXCR
T24167	Inflachromene	ICM	Others
	Inflachromene (ICM) is an inhibitor of HMGB1 and HMGB expression with anti-inflammatory activity.Inflachromene reduces seizure severity in a mouse model of epilepsy by inhibiting HMGB1 translocation, inhibits endothelial...		Others
T35885	KRM-III		Others
	KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetate/fosfomycin/ionomycin-induced NFAT nuclear factor activation and T cell ...		Others
T39595	Disitamab vedotin	RC 48,RC-48,RC48	EGFR
	Disitamab vedotin (RC-48) is an antibo-active molecular conjugate (ADC) containing a monoclonal antibody against human epidermal growth factor receptor 2 (HER2) that binds to the cytotoxic agent MMAE via a degradable lin...		EGFR
T83658	SQLE-IN-1		Antifungal
	SQLE-IN-1 is a squalene epoxidase (SQLE) inhibitor with anti-tumor activity. It can inhibit the proliferation and migration of liver cancer cell line Huh7, inhibit the production of cellular cholesterol, and increase the...		Antifungal
T1574	Etoricoxib	Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine	COX
	Etoricoxib (MK-663) is a synthetic, nonsteroidal anti-inflammatory drug (NSAID) with antipyretic, analgesic, and potential antineoplastic properties. Etoricoxib specifically binds to and inhibits the enzyme cyclooxygenas...		COX
T68170	Xl-281
	XL-281 is a potent, selective, orally active inhibitor of wild-type and mutant RAF kinases with anti-tumor activity in multiple xenograft models; demonstrates biological activity by modulation of the RAF pathway in tumor...
T11449L	Golotimod	Gamma-D-glutamyl-L-tryptophan,SCV 07	Antibiotic
	Golotimod (SCV 07) is an antimicrobial dipeptide with immunomodulatory activity that significantly improves the efficacy of anti-tuberculosis therapy, induces thymic and splenic cell proliferation, modulates macrophage f...		Antibiotic
T1185	Rofecoxib	MK 966,MK-0966	COX
	Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of pheny...		COX
T27417L	Glutathione arsenoxide hydrochloride	GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)	Apoptosis , AChR
	Glutathione arsenoxide hydrochloride (Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)) is a potentially active anti-cancer molecule and inhibitor of tumour metabolism. glutathione arsenoxide hydrochloride ta...		Apoptosis , AChR
T12009	Telomerase-IN-1		Telomerase
	Telomerase-IN-1 is a telomerase inhibitor (IC50: 0.19 μM). telomerase-IN-1 activates hTERT expression through the endoplasmic reticulum stress (ERS) of the ER overreaction (EOR), which then induces ERS, leading to apopto...		Telomerase

Compounds

AZD3514

T6400

Synonym:

Target: Androgen Receptor

ICCB280

T8839

Synonym:

Target: Apoptosis, Others

Target: Others, Wnt/beta-catenin, Methionine Adenosyltransferase (MAT)

FB23-2

T7138

Synonym:

Target: Apoptosis, Others

1-Naphthohydroxamic acid

Target: Histone Methyltransferase

(Rac)-JBJ-04-125-02

T8872

Synonym: JBJ-04-125-02

Target: Apoptosis, JAK

Fedratinib

T1995

Synonym: TG-101348,SAR 302503

Target: Apoptosis, FLT, c-RET, JAK

Synonym: EGFR Inhibitor

Target: Apoptosis, EGFR

Citarinostat

T3661

Synonym: ACY241,HDAC-IN-2

Target: EGFR, FGFR, PDGFR, Src

Fedratinib hydrochloride hydrate

T9251

Synonym: TG-101348 hydrochloride hydrate,SAR 302503 hydrochloride hydrate

Target: Apoptosis, JAK

NG 52

T2028

Synonym: NG52,NG-52,Compound 52

Target: Apoptosis, DNA/RNA Synthesis

Synonym: MK 341,SB 252218

Target: RAAS, Prostaglandin Receptor

RO2959 Hydrochloride

T8867

Synonym: RO2959 HCl

Target: IL Receptor, Calcium Channel, Interleukin

BMS-202

T3146

Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2

Target: Apoptosis, PD-1/PD-L1

Fenoldopam mesylate

T6835

Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526

Target: Dopamine Receptor

W-7 hydrochloride

T20792

Synonym: W 7 HCl,W7 HCl,W-7 HCl

Target: CaMK, Apoptosis, Myosin, PDE

Dimethylaminomicheliolide HCl

Synonym: NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3

Target: Apoptosis, Reactive Oxygen Species

PU-WS13 hydrobromide

T5351L

Synonym: PU-WS13 hydrobromide (1454619-14-7 Free base)

Target: GPR

CCR-11

T25214

Synonym: CCR11,CCR 11

Target: Antibiotic

Metformin hydrochloride

T0740

Synonym: Metformin HCl,1, 1-Dimethylbiguanide hydrochloride,1,1-Dimethylbiguanide hydrochloride

Target: Mitophagy, AMPK, Autophagy

KRAS G12D inhibitor 18

T78212

Synonym: KRAS G12D IN 18

Synonym: 5-(4-iodobenzylidene)rhodanine

Topoisomerase II inhibitor 13

T67899

Synonym:

Target: Topoisomerase

Target: Apoptosis, Hedgehog/Smoothened, Smo

Patritumab

T76796

Synonym: U3-1287,AMG-888

Target: ERK, EGFR, Akt, HER

Synonym: RC 48,RC-48,RC48

Synonym: Arcoxia,MK-663,Tauxib,L-791456,Nucoxia,Desvenlafaxine

Synonym: Gamma-D-glutamyl-L-tryptophan,SCV 07

Target: Antibiotic

Rofecoxib

T1185

Synonym: MK 966,MK-0966

Target: COX

Glutathione arsenoxide hydrochloride

T27417L

Synonym: GSAO HCl,Glutathione arsenoxide hydrochloride(1271726-51-2 Free base)

Target: Apoptosis, AChR

カタログ番号	製品名	別名	ターゲット
TN2054	Periplocymarin		Calcium Channel
	Periplocymarin is a cardiac glycoside with anticancer potential isolated from Periploca sepium and Periploca graeca.		Calcium Channel
TN1237	3-O-Methylgallic acid	3,4-Dihydroxy-5-methoxybenzoic acid	Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
	3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) reduces cell proliferation in Caco-2 cells(IC50 = 24.1 μM) more effectively than anthocyanins and may offer protection against colon cancer after its formation ...		Apoptosis , NF-κB , OCT , DNA/RNA Synthesis , STAT
T8846	Beta-Escin	B-escin,AESCINE	Immunology/Inflammation related
	beta-Escin is a natural mixture of triterpenoid saponins isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.		Immunology/Inflammation related
T22455	Vindesine sulfate	DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS	Others
	Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule...		Others
T0687	Simvastatin	MK-0733,MK 733	Apoptosis , Mitophagy , Ferroptosis , HMG-CoA Reductase , Autophagy
	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cholesterol, and is also used for the prevention of cardiovasc...
T12581	Puerarin-4'-O-β-D-glucopyranoside	Puerarin4'-O-glucoside	Others
	Puerarin-4'-O-β-D-glucopyranoside (Puerarin4'-O-glucoside) is a natural product isolated from Pueraria lobata root having estrogenic activity and anti-proliferation in MCF-7 human breast carcinoma cells.		Others
T6S1101	Astragalin	Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,Kaempferol 3-β-D-glucopyranoside	Apoptosis , NF-κB
	Astragalin (Kaempferol 3-O-glucoside) is a biologically active natural flavonoid. It has a variety of pharmacological properties, including antioxidant, anti-inflammatory, anti-cancer, neuroprotective, and cardioprotecti...		Apoptosis , NF-κB
TN2233	Spathulenol		Antioxidant , Antifungal
	Spathulenol is a natural ingredient from Aristolochia yunnanensis that has anti-inflammatory, antioxidant, anti-proliferation, anti-ulcer and anti-mycobacterium activities. Spathulenol showed significant antioxidant acti...		Antioxidant , Antifungal
T4S1540	Myrislignan		Apoptosis , NF-κB
	Myrislignan has anti-inflammatory, and anti-cancer activities, it inhibited NF-κB signalling pathway activation, inhibited the proliferation of A549 cells in a dose- and time-dependent manner, it also significantly induc...		Apoptosis , NF-κB
T5S1882	Songorine	Napellonine,Zongorine,Bullatine G	Others , GABA Receptor
	Songorine (Napellonine) shows favorable anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.		Others , GABA Receptor
TN2225	Soyasapogenol B		Apoptosis , Autophagy
	Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.		Apoptosis , Autophagy
T2945	Germacrone		P450 , Antiviral , Influenza Virus
	Germacrone, a major active component found in Curcuma zedoaria oil product, shows anti-inflammatory, antiandrogenic, and antivirus activities. It also inhibits the proliferation of glioma cells by promoting apoptosis.		P450 , Antiviral , Influenza Virus
T5S0777	Phellodendrine chloride		Others
	Phellodendrine chloride has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others
TN1516	Cnidicin		NOS , NO Synthase
	Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr...		NOS , NO Synthase
T4S1943	Kirenol	Kirel	Wnt/beta-catenin
	1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...		Wnt/beta-catenin
TN1600	Eclalbasaponin I		Others
	Eclalbasaponin I has anti-oxidative, and antitumor activities, it reduces oxidative stress-induced neural cell death by autophagy activation, it can dose-dependently inhibit the proliferation of hepatoma cell smmc-7721 w...		Others
TN2091	Polygalacin D		Apoptosis , IAP
	Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxi...		Apoptosis , IAP
T6S0781	Phellodendrine	Phallodendrin	Others , NF-κB , Akt
	1. Phellodendrine (Phallodendrin) has anti-nephritic activity, may be due to its ability to inhibit the proliferation or the migration of macrophages and cytotoxic T lymphocytes in the glomeruli.		Others , NF-κB , Akt
T3411	Curdione	(+)-Curdione	P450
	Curdione ((+)-Curdione) inhibits CYP3A4 activity and the production of prostaglandin E2. Curdione inhibits proliferation of MCF-7 cells by inducing apoptosis. Curdione may be a candidate for anti-inflammatory and Y chemo...		P450
TJS0487	(-)-Syringaresinol	DL-Syringaresinol,Lirioresinol b	Others
	(-)-Syringaresinol (DL-Syringaresinol) is derived from the stems of Annona Montana. (-)-Syringaresinol inhibits the proliferation of human promyelocytic HL-60 cells through G1 arrest and induction of apoptosis and posses...		Others
T3398	Icaritin	Anhydroicaritin,Cycloicaritin	Apoptosis , JAK , STAT , Autophagy
	Icaritin (Anhydroicaritin) has hormone regulation activity and cardiovascular function improvement activity. Icaritin has anticancer activity, can induce S phase arrest and apoptosis, inhibit ENKL cell proliferation. Ica...		Apoptosis , JAK , STAT , Autophagy
T4S0999	(2S)-Isoxanthohumol	Isoxanthohumol	Virus Protease , HSV
	1. (2S)-Isoxanthohumol shows an antiviral activity towards herpes viruses (HSV1 and HSV2) and bovine viral diarrhea virus (BVDV). 2. Isoxanthohumol is a polyphenol with antioxidant, anti-inflammatory, and antiangiogenic ...		Virus Protease , HSV
TN1805	Isosilybin B		Apoptosis , Androgen Receptor
	Isosilybin B is a flavonolignan extracted from silymarin that exhibits anti-prostate cancer (PCA) activity, inhibits cancer cell proliferation, and contributes to G1-phase blockade and apoptosis.Isosilybin B induces degr...		Apoptosis , Androgen Receptor
TN2089	Platycodin D3		HCV Protease , NF-κB
	Platycodin D3 is a NF-κB inhibitor, it could as expectorants in diverse inflammatory pulmonary diseases, it can regulate the production and secretion of airway mucin; it can significantly enhance mitogen- and OVA-induced...		HCV Protease , NF-κB
T4S0867	Pogostone	DHELWANGIN	Apoptosis , Antibacterial , Autophagy
	1. Pogostone (DHELWANGIN) possesses potent anti-bacterial and anti-fungal activities, such as gram negative bacteria , gram positive bacteria, Escherichia coli. 2. Pogostone exhibits an immunosuppressive property by dire...		Apoptosis , Antibacterial , Autophagy
T3867	Alpinetin	(-)-alpinetin	BCL , PPAR
	Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he...		BCL , PPAR
TN6967	(R)-Isomucronulatol	(-)-Isomucronulatol,2H-1-Benzopyran-7-ol	Apoptosis
	(R)-Isomucronulatol (2H-1-Benzopyran-7-ol), a flavonoid that can be extracted from the leaves of Astragalus membranaceus, Sophora japonica, Sclerotium tigrinum, and Glycyrrhiza glabra, inhibits the proliferation and apop...		Apoptosis
T4518	Licochalcone D		ERK , NF-κB
	Licochalcone D may be a potential drug for human melanoma treatment by inhibiting proliferation, inducing apoptosis via the mitochondrial pathway and blocking cell migration and invasion. Licochalcone D has cardioprotect...		ERK , NF-κB
T5679	(E)-Ferulic acid	trans-Ferulic acid,(E)-Coniferic acid	BCL , Ferroptosis , Wnt/beta-catenin , Endogenous Metabolite
	(E)-Ferulic acid ((E)-Coniferic acid) causes the phosphorylation of β-catenin, resulting in proteasomal degradation of β-catenin and increases the expression of pro-apoptotic factor Bax and decreases the expression of pr...
T3S1513	(20R)-Protopanaxadiol	Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol	Others , Antibacterial
	1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...		Others , Antibacterial
T2S0618	β-Elemonic Acid	3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid	Apoptosis , Reactive Oxygen Species , COX
	β-Elemonic Acid (3-Oxotirucallenoic Acid) exhibits anti-inflammatory effects. Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are rel...		Apoptosis , Reactive Oxygen Species , COX
T8716	Physalin F		Apoptosis
	Physalin F is a natural blocker of CaV2.3 (R-type) and CaV2.2 (N-type) voltage-gated calcium channels.It is a secosteroid with potent anti-inflammatory and immunomodulatory activities. Physalin F induces apoptosis of PBM...		Apoptosis
TN3972	Epimedokoreanin B		Apoptosis , Others , Antibacterial
	Epimedokoreanin B (EKB), an isoprenylated flavonoid isolated from Korean Epimedium, exhibited anticancer activity in human non-small cell lung cancer (NSCLC) A549 and NCI-H292 cells.Epimedokoreanin B also possesses anti-...		Apoptosis , Others , Antibacterial
T5S2358	Dehydrocorydaline	Dehydrocorydalin,13-Methylpalmatine	BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
	1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...		BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
T3S0364	L-Arginine	L-Arg,(S)-(+)-Arginine	IL Receptor , Endogenous Metabolite , NO Synthase
	1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...		IL Receptor , Endogenous Metabolite , NO Synthase
T3402	20(S)-Ginsenoside Rg3	20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
	20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
T2P2806	Hederacolchiside A1	Raddeanoside R13	Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
	Hederacolchiside A1 (Raddeanoside R13) shows anti-leishmanial activity, it exhibits a strong antiproliferative activity on all stages of development of the parasite by altering membrane integrity and potential. Hederacol...		Apoptosis , ERK , MEK , Akt , PI3K , Parasite , mTOR
T3776	Rhapontigenin	Protigenin	P450 , Antibacterial , Antifungal
	Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. R...		P450 , Antibacterial , Antifungal
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
T3824	Jaceosidin		Apoptosis , BCL , COX , UGT
	Jaceosidin has anti-oxidative activity. Jaceosidin has anti-inflammatory activity, also a microglial inhibitor with anti-neuroinflammation activity. aceosidin has anticancer activity, modulates the ERK/ATM/Chk1/2 pathway...		Apoptosis , BCL , COX , UGT
T7027	EURYCOMANONE	Pasakbumin A	Others
	Eurycomanone (Pasakbumin A) is cytotoxic on HepG2 cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.Eurycomanone has anti-cancer activity, inhibits A549 lung cancer cell p...		Others
T3123	Allicin		ERK , IL Receptor , Others , IκB/IKK , p38 MAPK , TNF , ROS , Caspase , Antifection
	Allicin exerts antioxidant, bactericidal, anti-cancer, anti-inflammatory activities, it exerts an inhibitory immunomodulatory effect on intestinal epithelial cells. Allicin could significantly inhibit vascular smooth mus...
T6S0119	Dauricine		Apoptosis , Others , NF-κB
	1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important ro...		Apoptosis , Others , NF-κB
T4900	(±)-Methyl Jasmonate	(±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate	Others , Endogenous Metabolite
	Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate ((±)-Jasmonic Acid methyl ester)induces the synthesis of proteinase inhibitors in plant leaves. In cancer cells, it suppresses proliferation and induces apoptosis. Mo...		Others , Endogenous Metabolite
TN6872	Trypsin		Protease-activated Receptor
	Trypsin is a serine protease that can be isolated from fish to hydrolyze lysine or arginine carboxy-side proteins. With the anti-inflammatory activity, Trypsin could induce the cell membrane fusion of PDCoV-infected cell...		Protease-activated Receptor
T6S1917	Schisandrol B	Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B	P450 , Reactive Oxygen Species , Autophagy
	1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...		P450 , Reactive Oxygen Species , Autophagy
T4S0797	Berberine	Berberin,Umbellatine	Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy
	1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3....
T2S2215	Crebanine		Apoptosis , Others , Akt
	1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rat...		Apoptosis , Others , Akt
TN6638	(E)-6-O-(p-coumaroyl)scandoside methyl ester
	(E)-6-O-(p-coumaroyl)scandoside methyl ester shows moderate anti-proliferation effect on PC3 human androgen-independent prostate cancer cells.
TN6651	Picrasidine Q
	Picrasidine Q has the capacity of anti-cell transformation and anti-cancer, it might be a chemopreventive and chemotherapeutic agent by direct targeting FGFR2 and inhibiting cell proliferation of ESCC cells.
------------------------ More ------------------------

天然物製品

Periplocymarin

TN2054

Synonym:

Target: Calcium Channel

3-O-Methylgallic acid

TN1237

Synonym: 3,4-Dihydroxy-5-methoxybenzoic acid

Target: Apoptosis, NF-κB, OCT, DNA/RNA Synthesis, STAT

beta-Escin

T8846

Synonym: B-escin,AESCINE

Target: Immunology/Inflammation related

Vindesine sulfate

T22455

Synonym: DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS

Target: Others

Simvastatin

T0687

Synonym: MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Puerarin-4'-O-β-D-glucopyranoside

T12581

Synonym: Puerarin4'-O-glucoside

Target: Others

Astragalin

T6S1101

Synonym: Kaempferol 3-D-glucoside,Kaempferol 3-O-glucoside,kaempferol-3-glucoside,3-Glucosylkaempferol,Astragaline,Kaempferol 3-β-D-glucopyranoside

Target: Apoptosis, NF-κB

Spathulenol

TN2233

Synonym:

Target: Antioxidant, Antifungal

Myrislignan

T4S1540

Synonym:

Target: Apoptosis, NF-κB

Songorine

T5S1882

Synonym: Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Soyasapogenol B

TN2225

Synonym:

Target: Apoptosis, Autophagy

Germacrone

T2945

Synonym:

Target: P450, Antiviral, Influenza Virus

Phellodendrine chloride

Target: NOS, NO Synthase

Kirenol

T4S1943

Synonym: Kirel

Target: Wnt/beta-catenin

Target: Apoptosis, IAP

Phellodendrine

T6S0781

Synonym: Phallodendrin

Target: Others, NF-κB, Akt

Curdione

T3411

Synonym: (+)-Curdione

Target: P450

(-)-Syringaresinol

TJS0487

Synonym: DL-Syringaresinol,Lirioresinol b

Target: Others

Icaritin

T3398

Synonym: Anhydroicaritin,Cycloicaritin

Target: Apoptosis, JAK, STAT, Autophagy

(2S)-Isoxanthohumol

T4S0999

Synonym: Isoxanthohumol

Target: Virus Protease, HSV

Isosilybin B

TN1805

Synonym:

Target: Apoptosis, Androgen Receptor

Platycodin D3

TN2089

Synonym:

Target: HCV Protease, NF-κB

Pogostone

T4S0867

Synonym: DHELWANGIN

Target: Apoptosis, Antibacterial, Autophagy

Alpinetin

T3867

Synonym: (-)-alpinetin

Target: BCL, PPAR

(R)-Isomucronulatol

TN6967

Synonym: (-)-Isomucronulatol,2H-1-Benzopyran-7-ol

Synonym: trans-Ferulic acid,(E)-Coniferic acid

Target: BCL, Ferroptosis, Wnt/beta-catenin, Endogenous Metabolite

(20R)-Protopanaxadiol

T3S1513

Synonym: Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol

Target: Others, Antibacterial

β-Elemonic Acid

T2S0618

Synonym: 3-oxo Tirucallic Acid,Beta-Elemonic acid,3-Oxotirucallenoic Acid,Elemadienonic Acid

Target: Apoptosis, Reactive Oxygen Species, COX

Target: Apoptosis, Others, Antibacterial

Dehydrocorydaline

T5S2358

Synonym: Dehydrocorydalin,13-Methylpalmatine

Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy

L-Arginine

T3S0364

Synonym: L-Arg,(S)-(+)-Arginine

Target: IL Receptor, Endogenous Metabolite, NO Synthase

20(S)-Ginsenoside Rg3

T3402

Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

Hederacolchiside A1

T2P2806

Synonym: Raddeanoside R13

Target: Apoptosis, ERK, MEK, Akt, PI3K, Parasite, mTOR

Rhapontigenin

T3776

Synonym: Protigenin

Target: P450, Antibacterial, Antifungal

Target: Apoptosis, BCL, COX, UGT

EURYCOMANONE

T7027

Synonym: Pasakbumin A

Target: ERK, IL Receptor, Others, IκB/IKK, p38 MAPK, TNF, ROS, Caspase, Antifection

Dauricine

T6S0119

Synonym:

Target: Apoptosis, Others, NF-κB

(±)-Methyl Jasmonate

T4900

Synonym: (±)-Jasmonic Acid methyl ester,Methyl 2-(3-oxo-2-(pent-2-en-1-yl)cyclopentyl)acetate

Target: Others, Endogenous Metabolite

Trypsin

TN6872

Synonym:

Target: Protease-activated Receptor

Schisandrol B

T6S1917

Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B

Target: P450, Reactive Oxygen Species, Autophagy

Berberine

T4S0797

Synonym: Berberin,Umbellatine

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

Crebanine

T2S2215

Synonym:

Target: Apoptosis, Others, Akt

(E)-6-O-(p-coumaroyl)scandoside methyl ester

--------- More ---------

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00854	IL-1 alpha/IL-1A Protein, Human, Recombinant	Human	HEK293
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-01738	IL-1 alpha/IL-1A Protein, Mouse, Recombinant	Mouse	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPY-06981	IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)	Human	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPJ-00038	IL-7 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 a...
TMPJ-01464	IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)	Human	Human Cells
	Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or m...
TMPJ-01467	Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)	Human	E.coli
	Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPY-05176	AMH Protein, Human, Recombinant (His)	Human	HEK293
	Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ...
TMPY-05504	4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated	Rhesus	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-05376	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-05594	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-01743	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-05767	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-03156	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01007	VEGFC Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-03577	Pleiotrophin/PTN Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	HB-GAM belongs to the pleiotrophin family. During embryonic and early postnatal development, HB-GAM is expressed in the central and peripheral nervous system and also in several non-neural tissues, notably lung, kidney, ...
TMPY-00463	ENPP2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-02778	ENPP2 Protein, Human, Recombinant (His)	Human	HEK293
	ENPP2 (Ectonucleotide pyrophosphatase/phosphodiesterase family member 2), also referred as Autotaxin, is a secreted enzyme encoded by the ENPP2 gene. This gene product stimulates the motility of tumor cells, has angiogen...
TMPY-00834	IGF1R/CD221 Protein, Human, Recombinant (His)	Human	HEK293
	The insulin-like growth factor-1 receptor (IGF1R) is a transmembrane tyrosine kinase involved in several biological processes including cell proliferation, differentiation, DNA repair, and cell survival. This a disulfide...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N...
TMPY-01845	IL-10 Protein, Human, Recombinant (His)	Human	HEK293
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-05064	IL-10 Protein, Mouse, Recombinant	Mouse	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-01107	TIMP-1 Protein, Human, Recombinant	Human	HEK293
	TIMP metallopeptidase inhibitor 1, also known as TIMP-1/TIMP1, Collagenase inhibitor 16C8 fibroblast Erythroid-potentiating activity, TPA-S1TPA-induced proteinTissue inhibitor of metalloproteinases 1, is a natural inhibi...
TMPY-03547	IL-10 Protein, Human, Recombinant	Human	E. coli
	IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono...
TMPY-00740	SDF-1 Protein, Human, Recombinant (hFc)	Human	HEK293
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-02820	SDF-1 Protein, Human, Recombinant (isoform a)	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-02591	SDF-1 Protein, Human, Recombinant	Human	E. coli
	The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPH-02590	COL4A2 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Canstatin, a cleavage product corr...
TMPK-01018	B7-H3 Protein, Human, Recombinant (aa 29-245, His)	Human	HEK293
	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s...
TMPK-00455	IGF1R/CD221 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-00456	IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated	Human	HEK293
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPK-01016	B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled	Human	HEK293
	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s...
TMPK-00315	B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s...
TMPK-01017	B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)	Human	HEK293
	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s...
TMPK-00314	B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)	Human	HEK293
	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount s...
TMPK-00658	IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, prot...
TMPY-05836	IL-1 alpha/IL-1A Protein, Rat, Recombinant	Rat	E. coli
	IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli...
TMPK-01137	FAM3D Protein, Human, Recombinant (hFc)	Human	HEK293
	The physiological homeostasis of gut mucosal barrier is maintained by both genetic and environmental factors and its impairment leads to pathogenesis such as inflammatory bowel disease. A cytokine like molecule, FAM3D (m...
TMPY-03341	ASF1B Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	The histone chaperone anti-silencing factor 1a (ASF1a) interacts with MDC1 and is recruited to sites of DSBs to facilitate the interaction of phospho-ATM with MDC1 and phosphorylation of MDC1, which are required for the ...
TMPH-02439	CD40L Protein, Rhesus macaque, Recombinant (His)	Rhesus	E. coli
	Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Its cross-linking on T-cells generates a costimulatory signal which enhances the production of IL4 and IL10 in co...
TMPY-04906	RGMB Protein, Human, Recombinant (His)	Human	HEK293
	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investig...
TMPY-04916	RGMB Protein, Mouse, Recombinant (His)	Mouse	HEK293
	RGMB was knocked down in breast cancer cells by way of an anti-RGMB ribozyme transgene. Knockdown of RGMB resulted in enhanced capacities of proliferation, adhesion, and migration in breast cancer cells. Further investig...
TMPJ-00766	ANXA1 Protein, Human, Recombinant	Human	E. coli
	Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-infla...
TMPY-03416	TNFAIP8 Protein, Human, Recombinant (His)	Human	E. coli
	Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-al...
TMPJ-00439	BTNL6 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Butyrophilin-like 6 (BTNL6) is a member of the BTN/MOG Ig-superfamily and functions with BTNL1 as a regulator of immune cell proliferation. The Btnl6 gene is found only in mice. BTNL6 expression is coordinated as a heter...
TMPH-03081	ACE2 Protein, Paguma larvata, Recombinant (hFc)	Paguma larvata	HEK293
	Essential counter-regulatory carboxypeptidase of the renin-angiotensin hormone system that is a critical regulator of blood volume, systemic vascular resistance, and thus cardiovascular homeostasis. Converts angiotensin ...
TMPY-06528	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-06382	4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-00230	4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc)	Canine	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-06279	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated	Mouse	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
TMPY-06329	4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated	Mouse	HEK293
	CD137 (also known as 4-1BB) is a surface co-stimulatory glycoprotein originally described as present on activated T lymphocytes, which belongs to the tumor necrosis factor (TNF) receptor superfamily. It is expressed main...
------------------------ More ------------------------

IL-1 alpha/IL-1A Protein, Human, Recombinant

TMPY-00854

Species: Human

Expression System: HEK293

IL-1 alpha/IL-1A Protein, Mouse, Recombinant

TMPY-01738

Species: Mouse

Expression System: E. coli

IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)

TMPY-06981

Species: Human

Expression System: E. coli

IL-7 Protein, Mouse, Recombinant (His)

TMPJ-00038

Species: Mouse

Expression System: Human Cells

IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)

TMPJ-01464

Species: Human

Expression System: Human Cells

Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)

TMPJ-01467

Species: Human

Expression System: E.coli

AMH Protein, Human, Recombinant (His)

TMPY-05176

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated

TMPY-05504

Species: Rhesus

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)

TMPY-05376

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPY-05594

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)

TMPY-01743

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)

TMPY-05767

Species: Mouse

Expression System: HEK293

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)

TMPY-03156

Species: Mouse,Rat

Expression System: HEK293

VEGFC Protein, Human, Recombinant (His)

TMPY-01007

Species: Human

Expression System: HEK293

Pleiotrophin/PTN Protein, Mouse, Recombinant

TMPY-03577

Species: Mouse

Expression System: Baculovirus-Insect Cells

ENPP2 Protein, Cynomolgus, Recombinant (His)

TMPY-00463

Species: Cynomolgus

Expression System: HEK293

ENPP2 Protein, Human, Recombinant (His)

TMPY-02778

Species: Human

Expression System: HEK293

IGF1R/CD221 Protein, Human, Recombinant (His)

TMPY-00834

Species: Human

Expression System: HEK293

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

TMPY-02219

Species: H1N1

Expression System: E. coli

IL-10 Protein, Human, Recombinant (His)

TMPY-01845

Species: Human

Expression System: HEK293

IL-10 Protein, Mouse, Recombinant

TMPY-05064

Species: Mouse

Expression System: E. coli

TIMP-1 Protein, Human, Recombinant

TMPY-01107

Species: Human

Expression System: HEK293

IL-10 Protein, Human, Recombinant

TMPY-03547

Species: Human

Expression System: E. coli

SDF-1 Protein, Human, Recombinant (hFc)

TMPY-00740

Species: Human

Expression System: HEK293

SDF-1 Protein, Human, Recombinant (isoform a)

TMPY-02820

Species: Human

Expression System: E. coli

SDF-1 Protein, Human, Recombinant

TMPY-02591

Species: Human

Expression System: E. coli

COL4A2 Protein, Mouse, Recombinant (His)

TMPH-02590

Species: Mouse

Expression System: E. coli

B7-H3 Protein, Human, Recombinant (aa 29-245, His)

TMPK-01018

Species: Human

Expression System: HEK293

IGF1R/CD221 Protein, Human, Recombinant (His & Avi)

TMPK-00455

Species: Human

Expression System: HEK293

IGF1R/CD221 Protein, Human, Recombinant (aa 31-932, His & Avi), Biotinylated

TMPK-00456

Species: Human

Expression System: HEK293

B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

TMPK-01016

Species: Human

Expression System: HEK293

B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00315

Species: Human

Expression System: HEK293

B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)

TMPK-01017

Species: Human

Expression System: HEK293

B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)

TMPK-00314

Species: Human

Expression System: HEK293

IGF1R/CD221 Protein, Cynomolgus, Recombinant (His)

TMPK-00658

Species: Cynomolgus

Expression System: HEK293

IL-1 alpha/IL-1A Protein, Rat, Recombinant

TMPY-05836

Species: Rat

Expression System: E. coli

FAM3D Protein, Human, Recombinant (hFc)

TMPK-01137

Species: Human

Expression System: HEK293

ASF1B Protein, Human, Recombinant (His)

TMPY-03341

Species: Human

Expression System: Baculovirus-Insect Cells

CD40L Protein, Rhesus macaque, Recombinant (His)

TMPH-02439

Species: Rhesus

Expression System: E. coli

RGMB Protein, Human, Recombinant (His)

TMPY-04906

Species: Human

Expression System: HEK293

RGMB Protein, Mouse, Recombinant (His)

TMPY-04916

Species: Mouse

Expression System: HEK293

ANXA1 Protein, Human, Recombinant

TMPJ-00766

Species: Human

Expression System: E. coli

TNFAIP8 Protein, Human, Recombinant (His)

TMPY-03416

Species: Human

Expression System: E. coli

BTNL6 Protein, Mouse, Recombinant (His)

TMPJ-00439

Species: Mouse

Expression System: Human Cells

ACE2 Protein, Paguma larvata, Recombinant (hFc)

TMPH-03081

Species: Paguma larvata

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)

TMPY-06528

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06382

Species: Human

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc)

TMPY-00230

Species: Canine

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated

TMPY-06279

Species: Mouse

Expression System: HEK293

4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated

TMPY-06329

Species: Mouse

Expression System: HEK293

--------- More ---------

カタログ番号	製品名
L6100	Polyphenolic Natural Product Library	635 compounds
	A unique collection of 635 natural polyphenolic compounds for high throughput screening (HTS) and high content screening (HCS);
L6140	Saccharide and Glycoside Natural Product Library	362 compounds
	A unique collection of 362 saccharides and glycosides compounds can be used for HTS and HCS；
L2130	Anti-Cancer Metabolism Compound Library	1268 compounds
	A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS);
L6730	Anti-virus Traditional Chinese Medicine Monomer Library	268 compounds
	A collection of 268 TCM monomers with anti-virus activity. An effective tool for drug development and pharmacological studies.
L6740	Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library	382 compounds
	A collection of 382 TCM monomers with anti-colorectal activity. An effective tool for drug development and pharmacological studies.

ライブラリー

Polyphenolic Natural Product Library

L6100

Compounds: 635

Saccharide and Glycoside Natural Product Library

L6140

Compounds: 362

Anti-Cancer Metabolism Compound Library

L2130

Compounds: 1268

Anti-virus Traditional Chinese Medicine Monomer Library

L6730

Compounds: 268

Anti-Colorectal Cancer Traditional Chinese Medicine Compound Library

L6740

Compounds: 382